Structure of PDB 6s13 Chain g Binding Site BS01

Receptor Information
>6s13 Chain g (length=152) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLV
EQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLG
LRWLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKA
FA
Ligand information
>6s13 Chain a (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
...........<.<<<<......<<<..<<<<.<..<<<<<<<.....<<
<.<<....<<..<<..<<<......................>>>..>>>>
.......<<........<<<<<<...<<...<<<<..<..........<<
..<<....>>..>>....................................
........................>..>>>>..>>.>>>>>>.<<<....
<<<....<<<<<<.......>>>>>>..>>>......>>>..<<<<<<<.
.....>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>....>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>..........................................<<
...........<<<<<........>>>>>............>>.......
......<.((.....<<<<.....<<..))>>.......>>>>..>....
>.>>>>.>>>..........<<<((.....<<<....<<<.<<<<<<..<
<....<<<.......<<<<<<.....>>>>>>.....>>>......>>.>
>>>>>...<<..<.<<....<.<<<<...............<<.......
.>>.........................<<....>>.>>>>>....>>.>
...>>...>>>....>>>....<..<<.........<<<..........>
.>>......>>..>..........<<<<<<..<<..<<<<<<<<......
>>>>>>>>..>>...<...)).>.....>>>>>>.>>>..<<.......<
<<....>>>.....>>...>>>>.>.<....<<<<<<<.....<<<<<..
<<<<<...........<<........>>..........<<<<<<<.....
.<<<<.......<<<<<....>>>>>.....<<.....>>......>>.>
>..<<.<<<...<<<.........<<<<<.<<<....>>>...<<<....
..>>>....>>>>>......<<..<....<........<<......>>..
.....>...>......<<<<.......>>>>.........>>........
.......>>>.>>>>>....>>>>>>>.........>>>>>.......<<
<<<.....<<<..........................>>>.....>>>>>
.............<.<..<..........>..>.>..........>>>>>
......<<<<<<.........>>>>>>............>>>>>>>....
>.............<<<<.<<.......<<..<<<<....<.<<<<..<<
..............>>.>>>>>....>>>>..>>.......>>.>>>>..
.............<<<<<............>>>>>....
Receptor-Ligand Complex Structure
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PDB6s13 Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Resolution3.58 Å
Binding residue
(original residue number in PDB)		M1 P2 R3 K4 G5 S6 V7 K9 R10 V12 N28 K29 I30 M31 L32 D33 G34 K35 R36 G37 T38 A39 R41 I42 R95 K114 T115 E117
Binding residue
(residue number reindexed from 1)		M1 P2 R3 K4 G5 S6 V7 K9 R10 V12 N28 K29 I30 M31 L32 D33 G34 K35 R36 G37 T38 A39 R41 I42 R95 K114 T115 E117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6s13, PDBe:6s13, PDBj:6s13
PDBsum6s13
PubMed31391518
UniProtA0A077VHU6

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