Structure of PDB 6eml Chain g Binding Site BS01

Receptor Information

>6eml Chain g (length=60) Species: 559292 (Saccharomyces cerevisiae S288C)

AKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRFVNVTLVN
GKRRMNPGPS

Ligand information

>6eml Chain 2 (length=1675)

uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccaggacuuu
uacuuugaaaaaauuagaguguucaaagcaggcguauugcucgaauauau
uagcauggaauaauagaauaggacguuugguucuauuuuguugguuucua
ggaccaucguaaugauuaauagggacggucgggggcaucaguauucaauu
gucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagca
uuugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucgaag
augaucgucguagucuuaaccauaaacuaugccgacuagggaucgggugg
uguuuuuuuaaugacccacucggcaccuuacgagaaaucaaagucuuugg
guucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuuggaaacucaccagg
uccagacacaauaaggauugacagauugagagcucuuucuugauuuugug
ggugguggugcauggccguaguugguggagugauuugucugcuuaauugc
gauaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcug
guuauccacuucuuagagggacuauauggaaguuugaggacaggucugug
augcccuuagacguucugggccgcacgcgcgcuacacugacggagccagc
gagucuaaccuuggccgagaggucuugguaaucuugugaaacuccgucgu
gcuggggauagagcauuguaauuauugcucuucaacgaggaauuccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacgcu
aguaccgauugaauggcuuagugaggccucaggaucugcuuagagaucuc
agagcggagaauuuggacaaacuuggucauuuagaggaacuaauuuccgu
aggugaaccugcggaaggaucauua

...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>><.<.<<<<<<......((((((...<<....>>.....<<......>
>>>>>>>.>...>...<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<
.....>>>..>>>..>....>.>.....<<<<<<<<<.<<.....>>..>
>>>>>.>>>......<<..<...........>..>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>
>>>>.........<<<[[.....<.<<...<<<.<<....<<<<<<.<<<
<<...........>.>>>>.>>>>>>.......<<.....>.>......<
<<<<.<<.......<<...<.......>..<<<.....>>>....>>...
...>>.>>..>>>.........<....<<<<<.........))))))...
.>>>>>...>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.
<...<<<......>>>......>.>>>>>>..>>.......<<....>>.
..>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<
<......>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<
.<<<........>>>>>>>>>>>..>>>...<<..]]>>...>>.....>
>>.>>>.<<<......<<<<....>>>>....>>>..]]]].}..<<.<<
<<<<<<..<<.<<<<<<..<<<.<<<<<<................<<<<<
.<....<<<<<.....<..<<.<<<........>>>.>>.>....>>>>>
...<<.<<<.....<<<<<.<<<.<<<<<....>>>...<<<......>>
>...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>
>>...>>>>>..>>>>.>>....<..>.......>>>>>>>.>>>.....
..>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<<<<<<.....
.<<.....<<..<<<<....>>>>..>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>....<
<<<.<<....<<<<<<<<.<<<..<.<<..<...<<<<<<<.........
.>>>>>>>...>..>>.>..>>>.>>>>>>>>...>>.>>>>..<<<<<<
<<<....>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6eml Cryo-EM structure of a late pre-40S ribosomal subunit fromSaccharomyces cerevisiae.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): K15 K20 V21 E22 E25 P27 K28 P30 K31 R33 A34 R37 R42 R43 R55 M56 N57 P60
• Binding residue (residue number reindexed from 1): K14 K19 V20 E21 E24 P26 K27 P29 K30 R32 A33 R36 R41 R42 R54 M55 N56 P59

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0010494 cytoplasmic stress granule
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6eml, PDBe:6eml, PDBj:6eml
• PDBsum: 6eml
• PubMed: 29155690
• UniProt: P0CX33|RS30A_YEAST Small ribosomal subunit protein eS30A (Gene Name=RPS30A)