Structure of PDB 5ot7 Chain g Binding Site BS01 |
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| >5ot7 Chain 4 (length=2901)
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agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga
cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc
uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc
uuuugcgcggggggaaccuggggaacugaaacaucucaguacccagagga
gaggaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccag
ccuaaaccguccggcuuguccgggcggggucguggggcccucggacaccg
aauccccagccuagccgaagcuguugggaagcagcgccagagagggugaa
agccccguaggcgaaagguggggggauaggugaggguacccgaguacccc
gugguucguggagccaugggggaaucugggcggaccaccgccuaaggcua
aguacuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaa
agaaccccgggaggggagugaaauagagccugaaaccgugggcuuacaag
cagucacggccccgcaagggguuguggcgugccuauugaagcaugagccg
gcgacucacggucgugggcgagcuuaagccguugaggcggaggcguaggg
aaaccgaguccgaacagggcgcaagcgggccgcacgcggcccgcaaaguc
cgcggccguggacccgaaaccgggcgagcuagcccuggccagggugaagc
uggggugagacccaguggaggcccgaaccggugggggaugcaaaccccuc
ggaugagcuggggcuaggagugaaaagcuaaccgagcccggagauagcug
guucuccccgaaaugacuuuagggucagccucaggcgcugacuggggccu
guagagcacugauagggcuagggggcccaccagccuaccaaacccuguca
aacuccgaagggucccagguggagccugggagugagggcgcgagcgauaa
cguccgcguccgagcgcgggaacaaccgagaccgccagcuaaggccccca
agucugggcuaagugguaaaggauguggcgcggcgaagacagccaggagg
uuggcuuagaagcagccauccuuuaaagagugcguaauagcucacugguc
gaguggcgccgcgccgaaaaugaucggggcuuaagcccagcgccgaagcu
gcgggucugggggaugaccccaggcgguaggggagcguucccgaugccga
ugaaggccgacccgcgagggcggcuggagguaagggaagugcgaaugccg
gcaugaguaacgauaaagagggugagaaucccucucgccguaagcccaag
gguuccuacgcaauggucgucagcguaggguuaggcgggaccuaagguga
agccgaaaggcguagccgaagggcagccgguuaauauuccggcccuuccc
gcaggugcgauggggggacgcucuaggcuagggggaccggagccauggac
gagcccggccagaagcgcagggugggagguaggcaaauccgccucccaac
aagcucugcgugguggggaagcccguacgggugacaaccccccgaagcca
gggagccaagaaaagccucuaagcacaaccugcgggaacccguaccgcaa
accgacacaggugggcgggugcaagagcacucaggcgcgcgggagaaccc
ucgccaaggaacucugcaaguuggccccguaacuucgggagaaggggugc
ucccuggggugaugagccccggggagccgcagugaacaggcucuggcgac
uguuuaccaaaaacacagcucucugcgaacucguaagaggagguauaggg
agcgacgcuugcccggugccggaaggucaaggggaggggugcaagccccg
aaccgaagccccggugaacggcggccguaacuauaacgguccuaagguag
cgaaauuccuugucggguaaguuccgaccugcacgaaaagcguaacgacc
ggagcgcugucucggcgagggacccggugaaauugaacuggccgugaaga
ugcggccuacccguggcaggacgaaaagaccccguggagcuuuacugcag
ccugguguuggcucuuggucgcgccugcguaggauaggugggagccugua
aacccccgccuccgggugggggggaggcgccggugaaauaccacccuggc
gcggcugggggccuaacccucggauggggggacagcgcuuggcgggcagu
uugacuggggcggucgccuccuaaaagguaacggaggcgcccaaaggucc
ccucaggcgggacggaaauccgccggagagcgcaaggguagaagggggcc
ugacugcgaggccugcaagccgagcaggggcgaaagccgggccuagugaa
ccgguggucccguguggaagggccaucgaucaacggauaaaaguuacccc
ggggauaacaggcugaucucccccgagcguccacagcggcggggagguuu
ggcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaag
gguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgu
cgugagacaguucggucucuauccgccacgggcgcaggaggcuugagggg
ggcucuuccuaguacgagaggaccggaagggacgcaccucugguuuccca
gcugucccuccaggggcauaagcuggguagccaugugcggaagggauaac
cgcugaaagcaucuaagcgggaagcccgccccaagaugaggccucccacg
gcgucaagccgguaaggacccgggaagaccacccgguggaugggccgggg
guguaagcgccgcgaggcguugagccgaccggucccaaucguccgagguc
u |
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<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>
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....>>>>>>.>>...<<<<<<.....<......>......>>>>>.>..
.......<<....>>...<<<<<.....<<.....>>....>>>>>...(
((....<<<<<<<.......>>>>>>>......<<<<<<<<<....<<<.
..<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<....
.))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<
<<<<<.......>>>>>>>>>......<<<<<..<<<<>>>>>..)))..
....]].>>>>>>.]]...............<<....>>....]].....
....<<<<....>>>>.............}....>>>>>>>>>>>.....
..<<<<<<<<<<<....>>>>>>>>>>>...<.<........>.>.<<<<
<<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<.
...>>..<<<<.....>>>>......<............>.......>>>
>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<
<<<<......>>>>>>.....>>>...<<<..<<<<........>>>>.>
>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>
>..<<<<<<....<<<<<....>>>>><<<<<<<<<.....<<<<<<<<<
...<<<...<<<<<<<<...<<.<<.........>>.>>...>>>>>>>>
..>>.>...>>>>>>>>>.....>>>>>>>.>>..<<<<<<<.<<.....
.>>.>>>>>>>.....<<<......>>>...<<<<.<<<...<<<(((..
...<<<<<<...........<<..<<<<<<<.<.........<<<..<<<
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....<<<<<.<<<....>>>>>>>>...>>>..>>>>>..>.....>>>>
>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<
<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<..
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<<<<<<<<...<<<<....<<<<<.<<<..<<<<<.<<<<.<<..((((.
..>>>>>><<<...<<<<<<<<<<.<<<<<.<<.....>>>>>>>.>...
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.>>>>>.........>>>>...>>...>>>>>>>>>>>>>>>..>>....
.<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<
<<<<<.<<...............<<<<<.....<..>......>>>>><<
<<<<<<<<<<.....>>>>>>>>>>>>............<<<<<<<<<..
<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>
>>>.<<<<<..<<..<<<<<<<..<<<...<<...<<<<<....>>>>>.
..>>...>>>>>>>>..>>>>..<<<<.........>>>>.........<
...........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>
>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<......
..>>>>>..<<<<<<<<.(((.........<<<<.[[<<<<..<<<<<.<
<<.<<<<<.<<<<<<<<....<<.............<<<.....<.....
.......<<<....>>>.........>...............>>>....>
>...>.>>>>>>>...<<<<<....>>>>>....>>>>>.>>>..>>>>>
..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<
<<...<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>
...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))......
..<<<<<<.((..>>>>..))>>>>>>..............>>>>..]]>
>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....
>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>
>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<
<....>>>.>>>>........)))>>>>>>>>....<<<<<<<...<<<<
..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<
<<<<<<<<))))>>>>>>...>>>>>...>>>>.>>>>>...<<<....<
<<<<...........>>>>>....>>>.>>>>.......>>>>>>>...<
<.......>>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<
<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>.....>
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| PDB | 5ot7 The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors. |
| Resolution | 3.8 Å |
Binding residue
(original residue number in PDB) | K7 P8 Y9 T10 S12 R13 F15 V18 F21 I24 L37 K38 G41 G42 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 F53 R54 G56 H58 K59 R60 L61 Y62 R63 Y84 P86 R88 D99 G100 K102 L147 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 H201 K202 V205 L206 G207 K208 A209 R211 R213 W214 R218 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 G236 E237 G238 R239 A240 P241 R242 G243 R244 A247 S248 P249 W250 W252 T254 K255 G256 L257 K258 T259 R260 K261 R262 R263 K264 P265 S266 R268 F269 R273 R274 |
Binding residue
(residue number reindexed from 1) | K6 P7 Y8 T9 S11 R12 F14 V17 F20 I23 L36 K37 G40 G41 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 F52 R53 G55 H57 K58 R59 L60 Y61 R62 Y83 P85 R87 D98 G99 K101 L146 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 H200 K201 V204 L205 G206 K207 A208 R210 R212 W213 R217 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 G235 E236 G237 R238 A239 P240 R241 G242 R243 A246 S247 P248 W249 W251 T253 K254 G255 L256 K257 T258 R259 K260 R261 R262 K263 P264 S265 R267 F268 R272 R273 |
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