Structure of PDB 8y38 Chain f Binding Site BS01

Receptor Information
>8y38 Chain f (length=95) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAY
EINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIRED
Ligand information
>8y38 Chain a (length=1479) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacugauguuagcggcggacgggugaguaac
acguggauaaccuaccuauaagacugggauaacuucgggaaaccggagcu
aauaccggauaauauuuugacgcaugguucaaaagugaaagacggcuguc
acuuauagauggauccgcgcugcauuagcuaguugguaagguaacggcuu
accaaggcaacgaugcauagccgaccugagagggugaucggccacacugg
aacugagacacgguccagacuccuacgggaggcagcaguagggaaucuuc
cgcaaugggcgaaagccugacggagcaacgccgcgugagugaugaagguc
uucggaucguaaaacucuguuauuagggaagaacauauguguaaguaacu
gugcacaucuugacgguaccuaaucagaaagccacggcuaacuacgugcc
agcagccgcgguaauacguagguggcaagcguuauccggaauuauugggc
guaaagcgcgcguaggcgguuuuuuaagucugaugugaaagcccacggcu
caaccguggagggucauuggaaacuggaaaacuugagugcagaagaggaa
aguggaauuccauguguagcggugaaaugcgcagagauauggaggaacac
caguggcgaaggcgacuuucuggucuguaacugacgcugaugugcgaaag
cguggggaucaaacaggauuagauacccugguaguccacgccguaaacga
ugagugcuaaguguuaggggggccccuuagugcugcagcuaacgcauuaa
gcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaauuga
cggggacccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaaaucuugacauccucuagagauagaggacagguggug
caugguugucgucagcucgugucgugagauguuggguuaagucccgcaac
gagcgcaacccuuaagcuuaguugccaucaugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuaggagcuagc
cgucgaaggugggacaaaugauuggggugaagucguaacaagguagccgu
aucggaaggugcggcuggaucaccuccuu
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<...<<......>>...>>>>>......<<.......
.<<<<<<<..<<...<<<<<<<.<<<<.....<<<<<<....>>>>>>..
....>>>>......<<<.<.........>.>>>.......<..<.>..>.
.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>
>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<
<.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<
<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<
....>>>>.....>>>>...<<<<<<<.......<.<<<<<<<.......
.>>>>>>>.>........>>>>>>...>..<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<<..<<<.<<<<<<<.<<<<<<<<<.......<<<<<<..
...>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<<...<<<......>>>......>>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>..>>>>>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<<<.>>>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<.<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<.<<<<....>>>>.>>.<<<.<<<.
.<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>
>>>>.....<<<<.<<<<<<...<<<..<..>>>>....>>>>>>.....
<<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>.>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<..>>.>>>.>>
>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<
<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8y38 Synthetic macrolides overcoming MLS B K-resistant pathogens.
Resolution2.58 Å
Binding residue
(original residue number in PDB)		R2 Y4 Y50 N70 K81 R88 V91 R93
Binding residue
(residue number reindexed from 1)		R2 Y4 Y50 N70 K81 R88 V91 R93
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8y38, PDBe:8y38, PDBj:8y38
PDBsum8y38
PubMed38992047
UniProtP66596|RS6_STAAW Small ribosomal subunit protein bS6 (Gene Name=rpsF)

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