Structure of PDB 8etj Chain f Binding Site BS01

Receptor Information
>8etj Chain f (length=106) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQGHRLYVKAKHLSFQRSKHVIHPGTSIVKIEGCDSKEEAQFYLGKRVCY
VYKSSKAVRGSKIRVIWGTIARPHGNSGAVRARFVHNLPAKTFGSSLRVM
LYPSNI
Ligand information
>8etj Chain 1 (length=1817) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaaugggugguaaauuucauc
uaaagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucga
aagaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcug
aaagggaagcauuggaaaucaggucagcaucaguuuucgggggcggaaaa
agaauaagggaagguggcuuuccgggaguguuuauagcccuuguuguaau
acguccacuggggacugaggacugcggcuucgugccaaggaugcugacau
aaugguuuucaauggcccgucuacacggaccaaggagucuagcaucuaug
cgaguguuugggugaugaaaacccauccgcgaaaugaaagugaaugcagg
ugggaacgcccuuguggcgugcaccaucgaccgacccggaaguauggaag
gguuugaguaagagcauagcuguugggacccgaaagauggugaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaaacucagauc
aguuuuaugaguauguaaaaugagaguuucuagugggccauuuuugguaa
gcagaacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaa
uguacgcucaucagaagaaaagguguuaguucaucuagacagcaggacgg
uggccauggaagucggaauccgcuaaggaguguguaacaacucaccugcc
gaaugaacuagcccugaaaauggauggcgcuuaagcguacuacccauacc
ucaccgucuggguugaagcucagacgaguaggcaggcguggagguuugug
acgaagccuugggcgugagccugggucgaacagccucuagugcagaucuu
gguggaaguagcauucaaaugagaacuuugaagacugaaguggggaaagg
uuccaugugaacagcaguuggacauggguuccaaggugaacagccucuag
uugauagaacaauguagauaagggaagucggcaaaaugccacugucccua
ucuacuaucuagcgaaaccacagccuggggaacgggccaggcaaaaucag
cggggcuuguggcagucaagcggcgacauugcuuuccuaucauaccgaag
cagaauucgguaagcguuggacccacuaauagggacuacugaugaagugu
cgucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauc
auugguauuugcggcugccugacaaggcaaugccgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gauuuuuugguccgcaugauuuauauguauaaaaauagagguaggcuacu
cuccuguaucguagaagaugggcgaugguugaugaaacggaaguguuuua
uugacuuguccaugaaauuccaaucuugugcggaaucgaauccauugcau
acgacuuuaauguggaacgggguauuguaagcagcugcugagauuaagcc
uuuguucccaagauuug
.........................<<<<<........>>>>>.......
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<..
......<<.<<<<<<<.......>>>>>>>.>>........>....<<<<
<.<<<<<..<<<<<...<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>...>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<<......>>>>>
>..>>>..................................<<....>>..
.............<<<<....>>>>.........................
.........<<<<<<<<<<<<.<<<<<<<.<<<<<<<<<<<<<<<.....
...<<<<<<<......<.<<<<..>>>>..>......>>>>>>>......
.>>>>>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>..
..>>>>>>>>>>>>..<<<<....>>>><<<<<<....<<<<<<.<<<<<
<..<<<..<<<<<.......>>>>>..>>>...<<....>>.......<<
<<<..<<<<<.....>>>>>...>>>>>.<<<<<<<<....<<>>....>
>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<..>>>>>>.
.....>.>>..<<<<<<.......<<....>>...<<<<<<<<<<...<<
<.<<<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<.<<....
.>>.>>.>>>>....<<<......>>>...<<<<<<<...<<<(((....
.<<<<<<.....<<......<<<.<<<<<<<<<<.......<<<<<.<<.
...<<.........>>....>>.........<<......>>...>>>>>.
..>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>...>>>
>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<<<<.<<.
.....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>
>>><<.....<<.<<<<<<.......>>>>>><<<<<....<<<......
..<<<<<....<<.....>>..>>>>>..>>>.<<<<.....>>>>.>>>
>>..<<<<.....<<<<<<<.<<.........<.........>..>>.>>
>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<
..<.......<<<<<<...<<.>>...>>>>>><<<<<..<.<<<<<<<.
.....>>>>>>>...>.<<<..>>>.....>>>>>.>.>>>>>.....<<
<<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<.
..<<<<....<<<<<<<<<<....>>>>>..>>>>>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>>>.....<.<<<..<.<..........<<.......<<<<..<..>..>
>>>....>>........<<<<<....<<<<<<<<<<<<......>>>>>>
>>>>>>..>>>>>.............>.>..>>>.>.<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<..>>>...>>>....>>
>>.>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8etj Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q4 G5 H6 R7 Y9 Q18 R19 K21 H22 I24 H25 P26 K39 Q43 L46 G47 R49 Y54 K55 S57 K58 V60 R61 K64 R66 R74 H76 G77 N78 S79 R83 R85 H88 N89 P91 A92 K93 F95 G96 S97 N107
Binding residue
(residue number reindexed from 1)		Q2 G3 H4 R5 Y7 Q16 R17 K19 H20 I22 H23 P24 K37 Q41 L44 G45 R47 Y52 K53 S55 K56 V58 R59 K62 R64 R72 H74 G75 N76 S77 R81 R83 H86 N87 P89 A90 K91 F93 G94 S95 N105
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8etj, PDBe:8etj, PDBj:8etj
PDBsum8etj
PubMed36423630
UniProtQ9USG6|RL33B_SCHPO Large ribosomal subunit protein eL33B (Gene Name=rpl35a)

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