Structure of PDB 8eti Chain f Binding Site BS01

Receptor Information
>8eti Chain f (length=106) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQGHRLYVKAKHLSFQRSKHVIHPGTSIVKIEGCDSKEEAQFYLGKRVCY
VYKSSKAVRGSKIRVIWGTIARPHGNSGAVRARFVHNLPAKTFGSSLRVM
LYPSNI
Ligand information
>8eti Chain 1 (length=1579) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugauaagcgcaggaaaagaaa
auaaccaugauucccucaguaacgugaagcgggaaaagcucaaauuugaa
aucuggcaacauuucuuuuguuguccgaguuguaauuucaagaagcugcu
uugaguguagacgaucggucuaaguuccuuggaacaggacgucagagagg
gugagaaccccgucuuuggucgauuggauaugccauauaaagcgcuuucg
aagagucgaguugcagcucuaaauggguggucaucuaaagcuaaauauug
gcgagagaccgauagcgaacaaguagagugaucgaaagaugaaaagaacu
uugaaaagagaguuaaauaguacgugaaauugcugaaagggaagcauugg
aaaucagucuuaccugggugagaucaguagucucucgagacuaugcacuc
uaaccuggguaggucagcaucaguuuucgggggcggaaaaagaauaaggg
aagguggcuguuuauagcccuuguuguaauacguccacuggggacugagg
acugcggcuucgugccaaggaugcugacauaaugguuuucaauggcccgu
cuaacacggaccaaggagucuagcaucuaugcgaguguuugggugaugaa
aacccauccgcgaaggugggaacgcccuuguggcgugcaccaucgaaaga
gcauagcuguugggacccgaaagauggugaaccaucuaguagcugguucc
ugccgaaguuuccggauagcagaaacucagaucaguuuuaugaguaugua
aaaugagaguuucuagugggccauuuuugguaagcagaacuggcgaugcg
ggaugaaccgaacgugagguuaaggugccggaauguacgcucaucagaag
aaaagguguuaguucaucuagacagcaggacgguggccauggaagucgga
auccgcuaaggaguguguaacaacucaccugccgaaugaacuagcccuga
aaauggauggcgcuuaagcguacuacccauaccucaccgucuggguuagc
uuugagaagcucagacgaguaggcaggcguggagguuugugacgaagccu
ugggcgugagccugggucgaacagccucuagugcagaucuugguggaagu
agcagcgaaaccacagccuggggggccaggcaaaaucagcggcagucaag
cgcgacguugcuuuccuaucauaccgaagcagaauucgguaagcguggga
acugaugaagugucgucgcaaugguaauucaacuuaguacgagaggaacc
guugauucagaucauugguauuugcggcgccgcggagcuaucaucugccg
gauaacggcugaacgccucuaagccagaauccgugccagaaagcgacgaa
uguauaaaaauagagguaggcuacucuccuguaucguagaagaugggcga
ugguugaugaaacggaaguguuuuauugacuuguccaugaaauuccaucg
aauccauugcauacgacuuuaauguggaacgggguauuguaagcagcugc
ugagauuaagccuuuguucccaagauuug
........................<<<<<<....>>>>>.>.........
<<....>>..<<<<<......<<>>.....>>>>>..<<<..<.......
.<<.<<<<<<<.......>>>>>>>.>>........>....<<<<<.<<<
<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((......<<
<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>>>>.>>.
.......<<<<<<>>>>>>.....<<<<<..>>>>>..>>>.........
.........................<<....>>...............<<
<<....>>>>..................................<<<<<<
<<<<<<.....<<<<<<<<.<<<.<<.<<<<<<<..>>>>>>>>>...>>
>.>>>>>>>>..<<<<<<<<<<<<<<<<<<<<<<<........<<<<<<<
.................>>>>>>>.......>>>>>.>>>>>>>>>>...
.....<<<.....>>>....>>>>>>>>....>>>>>>>>>>>>..<<<<
.....>>>><<<<<<....<<<<<<.<<<<<<..<<<...<<<<......
.>>>>...>>>...<<<<<..<<<<<.....>>>>>...>>>>>......
>>>>>>.>>>>>>..<<.<...<<<<<<..>>>>>>......>.>>..<<
<<<<......<<..>>..<<<<<<<<<<...<<<.<<<<<<<....>>>>
>>>>>>>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<
<......>>>...<<<<<<<...<<<(((.....<<<<<<.....<<...
...<<<.<<<<<<<<<<.......<<<<<.<<....<<.........>>.
...>>.........<<......>>...>>>>>...>>>>>>>>>>>>>..
........))).>>...>>>>>>.>>>...>>>>>>><<<<<<<<<....
........>>>>>>>>>....>>>>>>..<<<<<<<<.<<......<<<<
.<<<<....>>>>>>>>...>>>>>>>>>>........>>>>>><<....
.<<.>>....>>....<<<<<....>>>>>....<<<<<.<<<<<<...<
..>...>>>>>>.<<<...<.<<<<<<<......>>>>>>>...>.>>>.
.>>>>>......<<<<<<<..<<<<.<.<<<<<.................
>>>>>.><<<<<....<.<....<<<<..>>>>...>.>...>>>>>.<<
<<....<<<<...........>>>>....>>>>.>>>>....>>>>>>>.
...<<.......<<<<<<...>>.>>>>....>>........<<<<<...
.<<<<<<<<<<<<......>>>>>>>>>>>>..>>>>>..........<<
<<<<.<.............>.....<<<<<<<<<.<<<....<<<..>>>
...>>>....>>>>.>>>>>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8eti Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		A3 Q4 H6 R7 Q18 R19 S20 K21 H22 I24 K39 L46 R49 Y54 R66 W69 A73 R74 H76 G77 N78 S79 R83 H88 N89 P91 A92 K93 N107
Binding residue
(residue number reindexed from 1)		A1 Q2 H4 R5 Q16 R17 S18 K19 H20 I22 K37 L44 R47 Y52 R64 W67 A71 R72 H74 G75 N76 S77 R81 H86 N87 P89 A90 K91 N105
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8eti, PDBe:8eti, PDBj:8eti
PDBsum8eti
PubMed36423630
UniProtQ9USG6|RL33B_SCHPO Large ribosomal subunit protein eL33B (Gene Name=rpl35a)

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