Structure of PDB 8cqw Chain f Binding Site BS01

Receptor Information
>8cqw Chain f (length=55) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHENVWFSHPRNFGKGSRQCRHCSSHSGLIRKYGLDLCRQCFREKAADIG
FNKYR
Ligand information
>8cqw Chain B (length=1741) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguacccuacuuggauaaccguggu
aauucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggaugu
auuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaau
aacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuuc
ugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacg
gguaacggggaauaaggguucgauuccggagagggagccugagaaacggc
uaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacac
ggggagguagugacaauaaauaacgauacagggcccuuuugggucuugua
auuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggca
agucuggugccagcagccgcgguaauuccagcuccaaaagcguauauuaa
aguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcuggccg
ggcguacuggacccagccgagccuuuccuucuggguagccgaaccaggac
uuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucgaauau
auuagcauggaauaauagaauaggacguuaugguucuauuuuguugguuu
cuaggaccaucguaaugauuaauagggacggucggggguaucaguauuca
guugucagaggugaaauucuuggauuuacugaagacuaacuacugcgaaa
gcauuuaccaaggacguuuucauuaaucaagaacgaaaguuaggggaucg
aagaugaucagauaccgucguagucuuaaccauaaacuaugccgacuagg
gaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaaauca
aagucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggaguggagccugcggcuuaauuugacu
caacacggggaaacucaccagguccagacacaauaaggauugacagauug
agagcucuuucuugauuuugugggugguggugcauggccguucuuaguug
guggagugauuugucugcuuaauugcgauaacgaacgagaccuuaaccua
cuaaauagugcugcuagcauuugcugguauagucacuucuuagagggacu
aucgauuucaagucgauggaaguuugaggcaauaacaggucugugaugcc
cuuagacguucugggccgcacgcgcgcuacacugacggagccagcgagua
uaagccuuggccgagaggucugggaaaucuugugaaacuccgucgugcug
gggauagagcauuguaauuguugcucuucaacgaggaauuccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauugaauggcuuagugaggccuccggauugguuua
uucuggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<............<<.....<..<<..
.....>>..>......>>........<<<<<..<<....>>..>>>>><.
..<<<<<<.......((((((.<<<....>>>..............>>>>
>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>
>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>
>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>
>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>
>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>>>>
.>>>......<<..<...........>..>>.........<<<<<((...
...<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>.
........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<.....
..............>>>>>>>>>>.....<<<<...........>>>>..
..<<<<<.<<.......<<...<.......>..<<<....>>>....>>.
.....>>.>>..>>>.........<<<..<<<<<<<<......)))))).
..>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<.<...<<<......>>>......>.>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..]]>>.
..>>.....>>>.>>>.<<<......<<<<....>>>>....>>>..]]]
].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<...
.....>>..........<<<<<......<<<<<........<<.<<<...
.....>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.
<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..
<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....
<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>>>>>
>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<......<<..
....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>......
<....<<<<<<..........>>>>>>....>.....>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<.
.<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<<...
.......>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.05 Å
Binding residue
(original residue number in PDB)
A2 H3 V6 W7 F8 S9 H10 R12 F14 K16 G17 R19 C24 H27 G29 L30 I31 R32 K33 Y34 R40 Q41 R44 Y55 R56
Binding residue
(residue number reindexed from 1)
A1 H2 V5 W6 F7 S8 H9 R11 F13 K15 G16 R18 C23 H26 G28 L29 I30 R31 K32 Y33 R39 Q40 R43 Y54 R55
External links
PDB RCSB:8cqw, PDBe:8cqw, PDBj:8cqw
PDBsum8cqw
PubMed
UniProtA0A1D8PTR4|RS29A_CANAL Small ribosomal subunit protein uS14 (Gene Name=CAALFM_CR08480CA)

[Back to BioLiP]