Structure of PDB 7ase Chain f Binding Site BS01

Receptor Information
>7ase Chain f (length=1523) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSSRYRELIAIFGEFLEENDFHVRISMDRVGEVKTLFSAKTIPVESETEA
AIEVVTIEAARRRDALRRTCNAVLRTRHSDQHVDVGTIVADEEERLAWKF
LIGALAAKNSEILPVVEAELLLAAVEYHYATARPELCDMFVHLSASEMFF
IDGDSLFMAALSPQSVDWDLIQPLHVIYNAQKLLYDMHCRGARFHVVFFD
SLLWIWESAPAKLFMRENLRKTLMSLSENDAKVGLSISNFSSYYSEAFET
YVKQWEPEFILMSDGEQLGRLNPLQAFFVRPSAANNTHDSRRKANYTDAD
EANPYRLRRQYRSIVEDEAVGDKSDDDAGGNSANNKTAGAKKVNKEHAGQ
RNKKERSKEDEIRERSNVIAATATVAEWHKQMNHLLHAVDMSHGRTTNRD
RDESINTIMAAIKRLSQEKFGKNFDPGYTLGGSTNTAVPLKLEMWRLLVA
ASQLREVEFAFAMEDPALKDSKGASKKKDSKSEYKMLYGFHVINQFVERE
AVKGNHWGQLDPLRKAKPDMTIVEARSYLRWVYLSFVEMHIQLKLKCRVV
KLQLENWRAERERARLAQESPKIALGIPLFLYCHHHVLAVIRDEGPRMSS
EDIDTVRSALKHFDLPDSYYNKLDQCIARWQNMTLGTLLPSLLPQDKQLF
ETPEMLQLIHMGHLLERPFVREHDYRVAFNPDNWQRELLDIVDGRGSAVV
CAPTSAGKTFISYYCMYKALRRTNKKVVVYLAPARALINQAVADVCARYG
SKKYKNPGRYIYGALGGADYHQFHDSCQVLLTVPETFETMLLSPKYTDWV
ELIDYVILDEIHSMESNGNGDVWERILALLPCPFVALSATLGETQQLCSW
LNRVQGRLKEQTEEMSGKMRDFEVHLLPSEGKSIQRWNDIKKYIYLPPPG
AALTQKKIKAQYNNCYIRDLHPLSILTADQLQRGFPPDISLVPSEVVSLF
EKMHSKFNEVVWPNYSSLQLAKTLRAQLMLIEPSKYFEAETYITQERARQ
YEAEVKNAFAYWAYLGHEGCELPENLVEEDLDDFSASMNMAVESILRTFA
QKLNEDEALLERHAADGMEKKKRMLLRQQHLQLLQQQEQENEPNQEESME
QKSEEQGGAQEEEQEKETVGSVSFPGSRQFIREHILNVLRELIARDMGPT
IVFSFESEDCGDLVKYVVEQLEEAESRYRKTNEFALYKARIERAAAAQEA
RRKQRESTLKQKRLTTGDDGDVEVADRDMSDGEGEDELFVVPDVLPEFTF
IGEKCTVEPEVVDSLMEDCEKEGEDLLLRALQRGIGMHHAGVKGKLRAHV
ERLFRGRHCGVIFSTETLALGIHSPCRSVVLAGDHILLNPTQFRQMMGRA
GRRGLDYLGHLVFLGITMRRIKRLMTSSMTVIKGNVQMDPISNLRLLQLY
DFNTLRHLKNEAGWKTHVLKLAERLFVNPLFFQGRNSVAGGNMEGFTVEW
LQMLLGYFQREGLHFSDHASSLGSILQDAMYVFREAHVGNEGFSFIRMLT
SGVFDKAHYSPLYDKKLNSGVLD
Ligand information
>7ase Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcaccguggcgcaguggaagcgcgaugggcucauaacccauaggacguu
ggaucgaaaccaaccggugcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ase Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Resolution3.33 Å
Binding residue
(original residue number in PDB)		Q1548 S1551 K1554
Binding residue
(residue number reindexed from 1)		Q1204 S1207 K1210
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ase, PDBe:7ase, PDBj:7ase
PDBsum7ase
PubMed33357443
UniProtQ4E5Z1

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