Structure of PDB 6cb1 Chain f Binding Site BS01

Receptor Information
>6cb1 Chain f (length=106) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAY
VYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIF
LYPSNI
Ligand information
>6cb1 Chain 1 (length=1370) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaaaagcggaggaaaaga
aaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaa
auuugaaaucugguaccuucggugcccgaguuguaauuuggagagggcaa
cuuuggggccguuccuugucuauguuccuuggaacaggacgucauagagg
gugagaaucccguguggcgaggagugcgguucuuuguaaagugccuucga
agagucgaguuguuuugcagcucuaagugggugguaaauuccaucuaaag
cuaaauauuggcgagagaccgauagcgaacaaguacagugauggaaagau
gaaaagaacuuugaaaagagagugaaaaaguacgugaaauuguugaaagg
gaagggcauuugaucagacaugguguuuugugcccucugcuccuuguggg
uaggggaaucucgcauuucacugggccagcaucaguuuugguggcaggau
aaauccauaggaauguagcuugccucgguaaguauuauagccugugggaa
uacugccagcugggacugaggacugcgacguaagucaaggaugcuggcau
aaugguuauaugccgcggaccaaggagucuaacgucuaugcgaguguuug
gguguaaaacccauacgcguagguuggggccucgcaagaggugcacaauc
gaccgauccugaugucuucggauggauuugaguaagagcauagcuguugg
gacccugguuccugccgaagaacguagaguuaaggugccggaauacacgc
ucaucagaggcgcucaagcguguuaccuauacucuaccgucaggguugau
augaugcccugacgaguaggcaggcguggaggucagugacgaagccuaga
ccguaaggucgggucgaacggccucuagugcagaucuuggugguaguagc
aaauggguuagucgauccuaagagauggggaagcuccguuucaaaggccu
gauuuuaugcaggccaccaucgaaagggaauccgguuaagauuccggaac
cuggauauggauucuucacgguaacguaacugaauguggagacgucggcg
cgagcccugggaggaguuaucuuuucuucuuaacagcuuaucaccccgga
auugguuuauccggagauggggucuuauggcuggaagaggccagcaccuu
ugcuggcuccggugcgcuugugacggcccgugaaaauccacaggaaggaa
uaguuuucaugccaggucguacuugauagaauaaucuagcgaaaccacaa
uauagauggauacgaauaaggcguccuuguggcgucgcugaaccauagca
ggcuauggcgaauugcaaug
..........................<<<<<<....>>>>>.>.......
..<<....>>..<<<<<......<<.....>>.....>>>>>..<<<..<
........<<.<<<<<<...>>>>>>.>>........>....<<<<<<<.
<<<.<<<<<<<<<<<<<<<<<....<<<<......>>>>.(.......<<
<......)>>>..>.>>>>>>>>>..>>>>>>>.....>>>>>>>>>>..
......<<<<<<<...>>>>>>>.....<<<<<<......>>>>>>..>>
>..................................<<....>>.......
........<<<......>>>..............................
....<<<<<.<<<<<<.....<<<<...<<<<.<<<<<<<<<.....>>>
>>>>>>.....>>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<...
..<<<<<<<<<......<<<<<<....>>>>>>.......>>>>>>>>..
>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>>..
..>>>>>>.>>>>>....<<<<<<....<<<<<<.<<<<<<..<<<...<
<<<.....>>>>...>>>...<<<<<..<<<<<....>>>>>...>>>>>
.<<<<<<<<...<......>...>>>>.>>.>>....>>>>>>.>>>>>>
..<<..>>..<<<<<<.......<<<<<<<..<<<<(((.....<<<<<<
.....<<.))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<....
.....>>>>>>>>>....>>>>>>..<<<<<<<<.<<......<<<<.<<
<<....>>>>>>>>...>>>>>>>>>>........>>>>>><<.....<.
..........((<<<<<<...<<....<<<....>>>........<<<<<
<........>>>>>>....>>....>>...<<<<<........>>>>>))
<<<<.<<<<<<<.....<<<....>>>.......<<<<<<...<<<<.<<
<<<<<.<<<<<<<<<<.......>>>>>><...<<<<<....<<<<<<..
..<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<.....
.>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>........
..>>>..>>>>>>>>>>>>.......<<<<....>>>>.>....>>....
.......<<..........<<<<<<.....>>>>>>......>>......
.<<<..>>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cb1 Modular assembly of the nucleolar pre-60S ribosomal subunit.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		A2 S4 H5 R18 K20 R21 L45 K57 S62 I64 G76 N77 S78 N88 L89 P90 A91 K92 T93 F94 A96 S97
Binding residue
(residue number reindexed from 1)		A1 S3 H4 R17 K19 R20 L44 K56 S61 I63 G75 N76 S77 N87 L88 P89 A90 K91 T92 F93 A95 S96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6cb1, PDBe:6cb1, PDBj:6cb1
PDBsum6cb1
PubMed29512650
UniProtP05744|RL33A_YEAST Large ribosomal subunit protein eL33A (Gene Name=RPL33A)

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