Structure of PDB 7a01 Chain e3 Binding Site BS01

Receptor Information
>7a01 Chain e3 (length=124) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDE
PMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSC
VVVKDYGKESQAKDVIEEYFKCKK
Ligand information
>7a01 Chain K3 (length=1801) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
ggcgggcgccggcggcuuuggugacucuagauaaccucgggccgaucgca
cgccccccguggcggcgacgacccauucgaacgucugcccuaucaacuuu
cgaugguagucgccgugccuaccauggugaccacgggugacggggaauca
ggguucgauuccggagagggagccugagaaacggcuaccacauccaagga
aggcagcaggcgcgcaaauuacccacucccgacccggggagguagugacg
aaaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagucc
acuuuaaauccuuuaacgaggauccauuggagggcaagucuggugccagc
agccgcgguaauuccagcuccaauagcguauauuaaaguugcugcaguua
aaaagcucguaguuggaucuugggagcgggcgggcgcgcccguccccgcc
ccuugccucucggcgcccgggcccgaagcguuuacuuugaaaaaauuaga
guguucaaagcaggcccgagccgccuggauaccgcagcuaggaauaaugg
aauaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauu
aagagggacggccgggggcauucguauugcgccgcuagaggugaaauucu
uggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuu
cauuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucg
uaguuccgaccauaaacgaugccgaccggcgaugcggcggcguuauuccc
augacccgccgggcagcuuccgggaaaccaaagucuuuggguuccggggg
gaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccac
caggaguggagccugcggcuuaauuugacucaacacgggaaaccucaccc
ggcccggacacggacaggauugacagauugauagcucuuucucgauuccg
ugggugguggugcauggccguucuuaguugguggagcgauuugucugguu
aauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccc
cgagcggucggcgucccccaacuucuuagagggacaaguggcguucagcc
acccgagauugagcaauaacaggucugugaugcccuuagauguccggggc
ugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccggc
aggcgcggguaacccguugaaccccauucgugauggggaucggggauugc
aauuauuccccaugaacgaggaauucccaguaagugcgggucauaagcuu
gcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccg
auuggaugguuuagugaggcccucggaucggccccgccggggucggccca
cggcccuggcggagcgcugagaagacggucgaacuugacuaucuagagga
aguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucauu
a
...<<<<<.{.[[[[>>>>><<<.<<<<<<...<.<<.........<<<.
<<<...<....<......<..........>.....>.>.......<<...
.....<<<......<<......<....................<<.....
<<.............>>......>>.........<<<<...<<<<<....
..>>>>>...>>>>....<<<<<......(((((......<....<<...
....>>......>................>>>>>...........<<<<.
.<<<......>>>.>>>>...>......>>....>>>.<<<....<<<..
...<<<<<<.........>>>>>>.>>>......>>>...<<<.<<<<..
..>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>
.>...>>>>>>.........<<<....<<<.....>>>..>>>......>
>.>.....<<.<<<<<<.<........>.>>.>>>>..>>....<.<<..
...............>>......>..<<<<<((......<<<<.....<<
..))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<[[.
....<.<<....<<.<<.....<<.<<<<<<<<<<..>>>>>..>>>>>>
>........<<<<.<<<<>>>>>>>>.....<<<<<<.<.......<<..
.<.......>..<<<.......>>>....>>......>.>>>..>>>...
.....<.....<<<.<.........)))))...>.>>>.....>....>>
....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>.
.....>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>>
>...>>....>>.>....<<<<<<<...<...<<<<.........>>>>.
..>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<.....
.>>>>>>>>>>.>..>>>...<<..]]>>...>>.....>>>.>.>.<<<
......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<
..<<<<...<<<.<<<<<<.......<........>...........<<<
<<.<....<<<<<........<<..<<........>>.>>.......>>>
>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<..
....>>>...>>.>>>....<<<.......<<.....<<.....<<.<<.
.<......>>>..>>.....>>.....>>........<<<<<.....>>>
>>........>>>....>>>.>>>.....>>>>>>>.....>.>>>>>..
.>>.>>>>.>>>.....<<.<<<................<<<.<<<<...
.>>>>.>>>..............>>>.>>......<.....<<<<<....
......>>>>>.....>......>>>>......<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>.......<<.<..<<<<.<<.
...<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<..<.......
..>..>>>>>>>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.
>>>>...>.>>.........<<<<<<<<<....>>>>>>>>>........
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7a01 The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R33 R36 E58 Y61 N82 L91 C92 K102 V103 V104 G105 C106 S107
Binding residue
(residue number reindexed from 1)		R25 R28 E50 Y53 N74 L83 C84 K94 V95 V96 G97 C98 S99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7a01, PDBe:7a01, PDBj:7a01
PDBsum7a01
PubMed33296660
UniProtG1SFR8|RS12_RABIT Small ribosomal subunit protein eS12 (Gene Name=RPS12)

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