Structure of PDB 8fn2 Chain e Binding Site BS01

Receptor Information
>8fn2 Chain e (length=51) Species: 224326 (Borreliella burgdorferi B31) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVELISLICEETGIRNYTTTKNRRNKQEKLELMKYCPKLRKHTLHKEGKI
K
Ligand information
>8fn2 Chain A (length=2762) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggucaaaguaauaagagucuauggugaaugccuaggagcuuuaaggcga
agaaggucgugguaagcugcgaaaagcuugggggagaagcaaacauuuau
ugaucccaagauuaccgaauggaguaauccagcuagcaagaugcuagcua
ucuauuauuuaaauaauagaggcgauaccaggggaagugaaccaucuaag
uacccugaggaaaagaaaucaaagagauucccuuaguaguggcgagcgaa
aagggaguagcccaaacuuuaaaugugucaagcugcagagcguugcauuu
augggguuguaggacguuuaggcuuagucuguaauaagcaaaaaaguuac
aaaauauuuauauagaagaauaaucuggaaaguuuaaccaaagaagguga
uaguccuguaauuuaaauguaaauaucuuuuuaaaauguuccugaguagg
acgaggcacgagaaaccuuguuugaagcuggggagaccacucuccaaggc
uaaauacuagaaagcuaccgauagagaagaguaccgugagggaaagguga
aaagaaccccgggaggggagugaaauagaacugaaaccguagacuuacaa
gcagucaaagccguaauuuauugcggugauggcgugccuuuugcauaaug
aaccugcgaguuaucaugucuagcaagauuaaagcauagaagugcuggag
ucgaagcgaaagcgagucuuaaaagggcgauuuaguuagaugugguagac
ccgaagccgagugaucuauuuauggccaggcugaagcuuggguaaaacca
aguggagggccgaacucuagucuguuuaaaaaggcagggaugagcuguga
auaggagugaaaggcuaaacaaacucggagauagcugguucuccccgaaa
uggauuuaaguucagccuuauuuuaguuuaauagagguagagcacuaauu
gagcuagggccugucaaaggguaccaaacucaguuaaacuccgaaugcua
uuaaaugaugaauaggagugagacuaugggcgauaagguucauagucgag
agggaaacaacccagaccaacagcuaaggucucaaaaauguguuaagugg
aaaaggagguuuagguacguaaacagccaggagguuggcuuagaagcagc
cauaccuuuaaagagugcguaauagcucacuggucgaguacuuaagcgcc
gauaauguaacggggcuaaacacauuaccgaagcuuuggaucuuaacgaa
aguuaagaugguaggggagcguucuguaagccagagaaguuaagcuggaa
aguuugauggagguaucagaagugagaaugcagguaugaguaacgaaaaa
augggugagauucccauucgccgaaaaccuaagguuuccuggguaaaggu
cgucuucccaggguuagucggccccuaaggcaaagcugaaaaguguaguc
gaugggaaacggguuaauauucccguaccucuuauaguuucgauggagug
acgcaugagguuaacuacugcuaggcgaugguuguccuaguuuaagcauu
aaggcgaugaucuuaauaggaaaauccguuaagagagcuaagaugugaug
augagugcuauuuagguagcaugaaauguagguagucaaggugccaagaa
auagcuucuaagguuaggcuauaagggaccguaccgcaaaccgacacagg
uaggugggaugaaaauucuaaggcgcgcgagagaauccacguuaaggaac
ucugcaaaauacguacguaacuucgggauaaguacgaccuaagcaauuag
guagcauaaaaaugguccaaacgacuguuuaccaaaaacacaggucucug
caaaucuguaaagagaaguauagggacugacaccugcccggugcuaguaa
acggcuaagguagccggguaaguuccgacgaaugguguaacgauuuggac
gcugucucaacguggagcucggugaaauugaaguaucggugaagaugccg
auuacuugugguuagacggaaagaccccgugaaccuuuacuauagcuugg
uauugagauuugauuaauuaauuagguuucuaacuuauagaaauaugagg
agagugccagguggguaguuugacuggggcggucgccuccuaaagaguaa
cggaggugcgcaaagguuaccuuagagugguuggaaaucacucuguaagu
guaaaggcauaagguagcuuaacuguaagacugacaagucgaacagauac
gaaaguaggucuuagugaucuggcgguggcaaguggaagcgccgucacuu
aacgaauaaaagguacuccggggauaacaggcuuauccuucccaagaguu
cacaucgacggaaggguuuggcaccucgaugucggcucaucgcauccuag
ggcuggagcagguccuaaggguauggcuguucgccauuuaaagcgguacg
cgagcuggguucagaacgucgugagacaguuuggucccuaucugccacaa
gcguuggauauuugagaggagcuaucuuuaguacgagaggaccgagaugg
acgaaccucuagugugccaguuauccugccaaggguaagugcuggguagc
uacguucggaaaggauaaccgcugaaagcaucuaagugggaagccuuccu
caagaugagauauccuuuaaggguccuggaagaauaccagguugauaggu
uagaaguguaaguauagcaauauauuaagcugacuaauacuaauuacccg
uaucuuuggcca
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....<<<....>>>.......>>>>>>>.<<<<<..<<..<<<<..>>..
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>>..<<<<<<<<.<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<
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...>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<...<<<<<<<.<<<<<<<<.......>>>>>>>>...<<
.[.(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>.<<<
....>>>.>>)))]......<<<<<<<.<<..))))..>>>>>>>>>...
..........>>>>..>>>>>>.......<<<<.<.<<<<<<...<<...
....>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<
<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>
...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>>>>
>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>
.<<<<<...<<<<...<<<<<<<<<<<]]]]>>>>>>...>>>>>...>>
>>.>>>>>..<<<<....<<<<<...........>>>>>....>>>>>>>
>.......>>>>>>>.....<<<<<<<<<.......>>>>>....<<<<<
<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>.
...>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB8fn2 The structure of a hibernating ribosome in a Lyme disease pathogen.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
V10 Y25 T26 N30 K34 L38 L40 M41 K42 Y43 R48 K49 H50 I58 K59
Binding residue
(residue number reindexed from 1)
V2 Y17 T18 N22 K26 L30 L32 M33 K34 Y35 R40 K41 H42 I50 K51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8fn2, PDBe:8fn2, PDBj:8fn2
PDBsum8fn2
PubMed37907464
UniProtO51357|RL33_BORBU Large ribosomal subunit protein bL33 (Gene Name=rpmG)

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