Structure of PDB 8c3a Chain e Binding Site BS01

Receptor Information
>8c3a Chain e (length=62) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVTLAKVIKVLGRTGSRGGVTQVRVEFLEDASRTIVRNVKGPVRENDILC
LMESEREARRLR
Ligand information
>8c3a Chain B (length=1761) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccgcguacuggacccagccgagccuuuccuucuggguagccauuu
auggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuaugguu
cuauuuuguugguuucuaggaccaucguaaugauuaauagggacggucgg
ggguaucaguauucaguugucagaggugaaauucuuggauuuacugaaga
cuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaagaacg
aaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccauaa
acuaugccgacuagggaucgguuguuguucuuuuauugacgcaaucggca
ccuuacgagaaaucaaagucuuuggguucuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcuuaauuugacucaacacggggaaacucaccagguccagacacaaua
aggauugacagauugagagcucuuucuugauuuugugggugguggugcau
ggccguucuuaguugguggagugauuugucugcuuaauugcgauaacgaa
cgagaccuuaaccuacuaaauagugcugcuagcauuugcugguauaguca
cuucuuagagggacuaucgauuucaagucgauggaaguuugaggcaauaa
caggucugugaugcccuuagacguucugggccgcacgcgcgcuacacuga
cggagccagcgaguauaagccuuggccgagaggucugggaaaucuuguga
aacuccgucgugcuggggauagagcauuguaauuguugcucuucaacgag
gaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccugcc
cuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagugaggc
cuccggauugguuuaggaaauucuggaaccgagaagcuggucaaacuugg
ucauuuagaggaaguaaaagucguaacaagguuuccguaggugaaccugc
ggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<...............<<.....<..<
<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......((((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
....................>>>>>>>>>>.....<<<<<..........
........>>>>>....<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<<<<<<
<<......))))))...>>>>>>>>>>>.....>>....<<<<<<.<<..
.<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..
>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>.
...<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.....
.....<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>>>..
>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<....>
>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<
<<<<......<<........>>..........<<<<<......<<<<<..
......<<.<<<........>>>.>>......>>>>>...<<.<<<..<<
.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>>.>>
>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>
>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.....>
>.>>>.....>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<
<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.....
..>>>>>>>......<....<<<<<<..........>>>>>>....>...
..>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>
>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<
<..<...<<<<<<.............>>>>>>...>..>>>>..>>>.>>
>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>
>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c3a New crystal system to promote screening for new eukaryotic inhibitors
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R18 S21 R22 G23 P47
Binding residue
(residue number reindexed from 1)		R13 S16 R17 G18 P42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum8c3a
PubMed
UniProtA0A8H6C0A5

[Back to BioLiP]