Structure of PDB 8bp8 Chain e Binding Site BS01

Receptor Information
>8bp8 Chain e (length=397) Species: 28875 (Rotavirus A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGG
IGNLPIRNWNFNFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEM
VRESQRNGIAPQSDSLRKLSAIKFKRINFDNSSEYIENWNLQNRRQRTGF
TFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAIN
APANIQQFEHIVPLRRVLTTATITLLPDAERFSFPRVINSADGATTWFFN
PVILRPNNVEVEFLLNGQIINTYQARFGTIVARNFDTIRLSFQLMRPPNM
TPAVAVLFPNAQPFEHHATVGLTLRIESAVCESVLADASETLLANVTSVR
QEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8bp8 Chain e Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bp8 Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H153 K154
Binding residue
(residue number reindexed from 1)		H153 K154
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0046789 host cell surface receptor binding
GO:0046872 metal ion binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0044650 adhesion of symbiont to host cell
Cellular Component
GO:0019028 viral capsid
GO:0019031 viral envelope
GO:0039626 viral intermediate capsid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bp8, PDBe:8bp8, PDBj:8bp8
PDBsum8bp8
PubMed36996819
UniProtA2T3S6

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