Structure of PDB 7p7t Chain e Binding Site BS01

Receptor Information
>7p7t Chain e (length=200) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRYTGPSWKVSRRLGISLSGTGKELARRPYKPGQHGPNSRGKVSEYGMQL
TEKQKLRHMYGMNERQFRTLFIKASKIKEGKHGVNFMVLLEQRLDNVVYR
LGLATTRRQARQLVNHGHITVDGKRVDIPSYHVEVGQVIGVREKSQNIST
IKEAVEATVGRPAFVSFDTEKLEGSFTRLPERDELYPEIDEALVVEYYNQ
Ligand information
>7p7t Chain a (length=1521) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccuucggggacaaagugacagguggugcaugguugucgucagc
ucgugucgugagauguuggguuaagucccgcaacgagcgcaacccuuauu
guuaguugccaucauuuaguugggcacucuagcgagacugccggugacaa
accggaggaagguggggaugacgucaaaucaucaugccccuuaugaccug
ggcuacacacgugcuacaaugggaaguacaacgagucgcuagaccgcgag
gucaugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaac
ucgccugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcg
gugaauacguucccgggccuuguacacaccgcccgucacaccacgagagu
uuguaacacccgaagucggugagguaaccuuuuuggagccagccgccuaa
ggugggauagaugauuggggugaagucguaacaagguagccguaucggaa
ggugcggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>>>......>
>.>.......<<<<<<<<....>>>>>>>>.......<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<<.......<<<<<....>>>
>>...<<<<<..>>>>>...>>.>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>...........<<<<<<<......
..>>>>>>>..........>>>>>>....<<<<<<<.........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..
>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7p7t Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
S2 R3 P7 S8 W9 K10 R13 R14 R28 R29 Y31 P33 G34 Q35 H36 R41 S45 Y47 G48 L51 K54 Q55 R58 N64 E65 R66 Q67 R69 K77 T107 R109 Q110 R112 Q113 N116 H117 H119 V127 I129 S131 Y132 K145 Q201
Binding residue
(residue number reindexed from 1)
S1 R2 P6 S7 W8 K9 R12 R13 R27 R28 Y30 P32 G33 Q34 H35 R40 S44 Y46 G47 L50 K53 Q54 R57 N63 E64 R65 Q66 R68 K76 T106 R108 Q109 R111 Q112 N115 H116 H118 V126 I128 S130 Y131 K144 Q200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7p7t, PDBe:7p7t, PDBj:7p7t
PDBsum7p7t
PubMed35387982
UniProtA0A1B4XRV7

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