Structure of PDB 7p7q Chain e Binding Site BS01

Receptor Information
>7p7q Chain e (length=200) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRYTGPSWKVSRRLGISLSGTGKELARRPYKPGQHGPNSRGKVSEYGMQL
TEKQKLRHMYGMNERQFRTLFIKASKIKEGKHGVNFMVLLEQRLDNVVYR
LGLATTRRQARQLVNHGHITVDGKRVDIPSYHVEVGQVIGVREKSQNIST
IKEAVEATVGRPAFVSFDTEKLEGSFTRLPERDELYPEIDEALVVEYYNQ
Ligand information
>7p7q Chain a (length=1521) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccuucggggacaaagugacagguggugcaugguugucgucagc
ucgugucgugagauguuggguuaagucccgcaacgagcgcaacccuuauu
guuaguugccaucauuuaguugggcacucuagcgagacugccggugacaa
accggaggaagguggggaugacgucaaaucaucaugccccuuaugaccug
ggcuacacacgugcuacaaugggaaguacaacgagucgcuagaccgcgag
gucaugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaac
ucgccugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcg
gugaauacguucccgggccuuguacacaccgcccgucacaccacgagagu
uuguaacacccgaagucggugagguaaccuuuuuggagccagccgccuaa
ggugggauagaugauuggggugaagucguaacaagguagccguaucggaa
ggugcggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>>>......>
>.>.......<<<<<<<<<..>>>>>>>>>.......<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>>........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>....<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>......<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<<.......<<<<<....>>>
>>...<<<<<..>>>>>...>>.>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>......<....<<<<<<<......
..>>>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..
>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7p7q Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
S2 R3 T5 P7 S8 W9 K10 R13 R14 R28 R29 Y31 K32 P33 G34 Q35 H36 R41 S45 Y47 Q50 L51 K54 Q55 N64 E65 R66 R69 K77 T107 R109 Q110 R112 Q113 N116 H117 H119 V127 I129 S131 Y132 K145 E197 N200 Q201
Binding residue
(residue number reindexed from 1)
S1 R2 T4 P6 S7 W8 K9 R12 R13 R27 R28 Y30 K31 P32 G33 Q34 H35 R40 S44 Y46 Q49 L50 K53 Q54 N63 E64 R65 R68 K76 T106 R108 Q109 R111 Q112 N115 H116 H118 V126 I128 S130 Y131 K144 E196 N199 Q200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7p7q, PDBe:7p7q, PDBj:7p7q
PDBsum7p7q
PubMed35387982
UniProtQ82ZI6|RS4_ENTFA Small ribosomal subunit protein uS4 (Gene Name=rpsD)

[Back to BioLiP]