Structure of PDB 6vyp Chain e Binding Site BS01

Receptor Information
>6vyp Chain e (length=103) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMQTARKSTGYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKT
DLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRI
RGE
Ligand information
>6vyp Chain i (length=191) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgaccctatacgcggccgccctggagaatcccggtgccgaggccgctc
aattggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgtc
ccccgcgttttaaccgccaaggggattactccctagtctccaggcacgtg
tcagatatatacatcctgtgcatgtattgaacagcgacgat
Receptor-Ligand Complex Structure
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PDB6vyp Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Resolution4.99 Å
Binding residue
(original residue number in PDB)
Y41 V46 R49 R63 K64 L65 P66 R83
Binding residue
(residue number reindexed from 1)
Y11 V16 R19 R33 K34 L35 P36 R53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6vyp, PDBe:6vyp, PDBj:6vyp
PDBsum6vyp
PubMed32396821
UniProtP84233|H32_XENLA Histone H3.2

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