Structure of PDB 6o8x Chain e Binding Site BS01

Receptor Information
>6o8x Chain e (length=163) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNGHVGFGTGK
AQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGVFGGGRILMKPAVEG
SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEE
VAALRGKSVEEII
Ligand information
>6o8x Chain a (length=1528) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauaca
ugcaagucgaacgcuucuuuccuuggaaagaggaguggcggacgggugag
uaacacguggguaaccuacccaucagagggggauaacacuuggaaacagg
ugcuaauaccgcauaacaguuuaugccgcauggcauaagagugaaaggcg
cuuucgggugucgcugauggauggacccgcggugcauuagcuaguuggug
agguaacggcucaccaaggccacgaugcauagccgaccugagagggugau
cggccacacugggacugagacacggcccagacuccuacgggaggcagcag
uagggaaucuucggcaauggacgaaagucugaccgagcaacgccgcguga
gugaagaagguuuucggaucguaaaacucuguuguuagagaagaacaagg
acguuaguaacugaacguccccugacgguaucuaaccagaaagccacggc
uaacuacgugccagcagccgcgguaauacguagguggcaagcguuguccg
gauuuauugggcguaaagcgagcgcaggcgguuucuuaagucugauguga
aagcccccggcucaaccggggagggucauuggaaacugggagacuugagu
gcagaagaggagaguggaauuccauguguagcggugaaaugcguagauau
auggaggaacaccaguggcgaaggcggcucucuggucuguaacugacgcu
gaggcucgaaagcguggggagcaaacaggauuagauacccugguagucca
cgccguaaacgaugagugcuaaguguuggaggguuuccgcccuucagugc
ugcagcaaacgcauuaagcacuccgccuggggaguacgaccgcaagguug
aaacucaaaggaauugacgggggcccgcacaagcgguggagcaugugguu
uaauucgaagcaacgcgaagaaccuuaccaggucuugacauccuuugacc
acucuagagauagagcuuucccuucggggacaaagugacagguggugcau
gguugucgucagcucgugucgugagauguuggguuaagucccgcaacgag
cgcaacccuuauuguuaguugccaucauuuaguugggcacucuagcgaga
cugccggugacaaaccggaggaagguggggaugacgucaaaucaucaugc
cccuuaugaccugggcuacacacgugcuacaaugggaaguacaacgaguc
gcuagaccgcgaggucaugcaaaucucuuaaagcuucucucaguucggau
ugcaggcugcaacucgccugcaugaagccggaaucgcuaguaaucgcgga
ucagcacgccgcggugaauacguucccgggccuuguacacaccgcccguc
acaccacgagaguuuguaacacccgaagucggugagguaaccuuuuugga
gccagccgccuaaggugggauagaugauuggggugaagucguaacaaggu
agccguaucggaaggugcggcuggauca
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<<<<<......>>>>>>>.>>>>>......<<...
.....<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>
>>......>>.>.......<<<<<<<<<..>>>>>>>>>.......<<<<
........>>>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>
>>......<..<<<....<<<<....>>>>..>>>.>>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>...<<<<<<<.........<<
.<<<..........>>>..>>.........>>>>>>...>..<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
.........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<...
....<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>>
>>>>>>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>
...>>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<......>>>>>>>>>>>
>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>.
...>>>..)))).]<<....<<<<<<<.<<.<<<<<<..<<<<<<<<<<.
.....<<........>>..........<<<<<<<.......<<<......
.<<<<<....>>>>>.......<...>.....>.>.>...<<.<<<..<<
<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>
>.....<<<<.<<<<<<<..<<<...<......>.>>>...>>>>>>>..
...<<<<<.....>>>>>........>>>>.........>>>...>>>>>
>>>....>>>>>>>...>>.>>>>>>>>......<<<<<<.....<<<..
<<..<<<<....>>>>..>>....>>>.....>>>>>>.......<....
<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.
........>>>>>>>......>>...>>>>>>>....>>.......<<.<
.<<<<.<<<..<<<<<<..<<<<...<<.<<<<..<<<..<<.....>>.
>>>.>>>>.>>..>>>>..>>>>>>..>>>.>>>>..>.>>.........
<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB6o8x Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Resolution3.68 Å
Binding residue
(original residue number in PDB)
V21 T22 K23 V24 R29 K52 K97 A106 A107 G108 R112 S125 K126 S127 T132 N135
Binding residue
(residue number reindexed from 1)
V19 T20 K21 V22 R27 K50 K95 A104 A105 G106 R110 S123 K124 S125 T130 N133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6o8x, PDBe:6o8x, PDBj:6o8x
PDBsum6o8x
PubMed33004869
UniProtA0A1B4XKW0

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