Structure of PDB 6c0f Chain e Binding Site BS01

Receptor Information
>6c0f Chain e (length=114) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKIVKKHTKKFKRHHSDRYHRVAENWRKQKRGNISQPKIGYGSNKKTKFL
SPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISAKNRVVILARAKALG
IKVTNPKGRLALEA
Ligand information
>6c0f Chain 1 (length=1357) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaaaagcggaggaaaaga
aaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaa
auuugaaaucugguaccuucggugcccgaguuguaauuuggagagggcaa
cuuuggggccguuccuugucuauguuccuuggaacaggacgucauagagg
gugagaaucccguguggcgaggagugcgguucuuuguaaagugccuucga
agagucgaguuguuuugcagcucuaagugggugguaaauuccaucuaaag
cuaaauauuggcgagagaccgauagcgaacaaguacagugauggaaagau
gaaaagaacuuugaaaagagagugaaaaaguacgugaaauuguugaaagg
gaagggcauuugaucagacaugguguuuugugcccucugcuccuuguggg
uaggggaaucucgcauuucacugggccagcaucaguuuugguggcaggau
aaauccauaggaauguagcuugccucgguaaguauuauagccugugggaa
uacugccagcugggacugaggacugcgacguaagucaaggaugcuggcau
aaugguuauaugccgcggaccaaggagucuaacgucuaugcgaguguuug
gguguaaaacccauacgcguagguuggggccucgcaagaggugcacaauc
gaccgauccugaugucuucggauggauuugaguaagagcauagcuguugg
gacccugguuccugccgaagaacguagaguuaaggugccggaauacacgc
ucaucagaggcgcucaagcguguuaccuauacucuaccgucaggguugau
augaugcccugacgaguaggcaggcguggaggucagugacgaagccuaga
ccguaaggucgggucgaacggccucuagugcagaucuuggugguaguagc
aaauugauagaauaaucuagcgaaaccaauguuaccgcaauaguaauuga
acuuaguacgagaggaacaguucauucggauaauugguuuuugcggcugu
gcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucuaag
ucagaauccaugcuagaacgcggugaucuccacacaauauagauggauac
gaauaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggu
gcacuuggcggaaaggccuugggugcuugcuggcgaauugcaauggcgug
gggauaaaucauuuguauacgacuuagauguacaacgggguauuguaagc
aguagaguagccuuguuguuacgaucugcugagauuaagccuuuguuguc
ugauuug
..........................<<<<<<....>>>>>.>.......
..<<....>>..<<<<<......<<.....>>.....>>>>>..<<<..<
........<<.<<<<<<...>>>>>>.>>........>....<<<<<<<.
<<<.<<<<<<<<<<<<<<<<<....<<<<......>>>>.(.......<<
<......)>>>..>.>>>>>>>>>..>>>>>>>.....>>>>>>>>>>..
......<<<<<<<...>>>>>>>.....<<<<<<......>>>>>>..>>
>..................................<<....>>.......
........<<<......>>>..............................
....<<<<<.<<<<<<.....<<<<...<<<<.<<<<<<<<<.....>>>
>>>>>>.....>>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<...
..<<<<<<<<<......<<<<<<....>>>>>>.......>>>>>>>>..
>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>>..
..>>>>>>.>>>>>....<<<<<<....<<<<<<.<<<<<<..<<<...<
<<<.....>>>>...>>>...<<<<<..<<<<<....>>>>>...>>>>>
.<<<<<<<<...<......>...>>>>.>>.>>....>>>>>>.>>>>>>
..<<..>>..<<<<<<.......<<<<<<<..<<<<(((.....<<<<<<
.....<<.))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<....
.....>>>>>>>>>....>>>>>>..<<<<<<<<.<<......<<<<.<<
<<....>>>>>>>>...>>>>>>>>>>........>>>>>><<.....<.
.......<<<<....>>>>.>....>>....<<<<<<<..<<<<...<<<
<<<...............>>>>>>..<<<<<...<<<<<<<.<<<<<.<.
.>...>>>>>>>>>>>>..>>>>>.<<<<...<<<<<...........>>
>>>...>>>>.>>>>....>>>>>>>.<<<<<<.<.........<<....
......<<<<<<.....>>>>>>......>>.......<<<<<<...<<<
<<.<..<<<......>>>..>.>>>>>.>>>>>>...........>.>>>
>>>.<<<<<<.<.............>.....<<<<<<<<<.<<<....<<
<<.<..<<<<<......>>>>>..>>>>>...>>>....>>>>.>>>>>.
.>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6c0f Modular assembly of the nucleolar pre-60S ribosomal subunit.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		K12 K15 F17 D23 R24 H26 R27 N31 W32 R33 K34 R47 P53 K54 I55 G56 Y57 G58 S59 N60 K61 K64 F65 L66 P68 L75 N78 E95 I96 A97 H98 N99 I100 S101 A102 K103 N104 R105 K113 N121 G124 R125 L128
Binding residue
(residue number reindexed from 1)		K6 K9 F11 D17 R18 H20 R21 N25 W26 R27 K28 R31 P37 K38 I39 G40 Y41 G42 S43 N44 K45 K48 F49 L50 P52 L59 N62 E79 I80 A81 H82 N83 I84 S85 A86 K87 N88 R89 K97 N105 G108 R109 L112
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6c0f, PDBe:6c0f, PDBj:6c0f
PDBsum6c0f
PubMed29512650
UniProtP38061|RL32_YEAST Large ribosomal subunit protein eL32 (Gene Name=RPL32)

[Back to BioLiP]