Structure of PDB 8scb Chain dd Binding Site BS01

Receptor Information
>8scb Chain dd (length=53) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFI
KLD
Ligand information
>8scb Chain 9 (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgccacuuggauaacugugguaauuc
uagagcuaauacaugccgacgggcgcugacccccuucgcgggggggaugc
gugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgccc
cccguggcggcgacgaccauucgaacgucugcccuaucaacuuucgaugg
uagucgccgugccuaccauggugaccacgggugacggggaaucaggguuc
gauuccggagagggagccugagaaacggcuaccacauccaaggaaggcag
caggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaau
aacaauacaggacucuuucgaggcccuguaauuggaaugaguccacuuua
aauccuuuaacgaggauccauuggagggcaagucuggugccagcagccgc
gguaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagc
ucguaguuggaucuugggagcgggcguccccgccuuuacuuugaaaaaau
uagaguguucaaagcaggcccgagccgccuggauaccgcagcuaggaaua
auggaauaggaccgcgguucuauuuugguuuucggaacugaggccaugau
uaagagggacggccgggggcauucguauugcgccgcuagaggugaaauuc
uuggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuu
ucauuaaucaagaacgaaagucggagguucgaagacgaucagauaccguc
guaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauucc
caugacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggg
ggaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcuuaauuugacucaacacgggaaaccucacc
cggcccggacacggacaggauugacagauugauagcucuuucucgauucc
gugggugguggugcauggccguucuuaguugguggagcgauuugucuggu
uaauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgaccc
ccgagcggucggcgucccccaacuucuuagagggacaaguggcguucagc
cacccgagauugagcaauaacaggucugugaugcccuuagauguccgggg
cugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccgg
caggcgcggguaacccguugaaccccauucgugauggggaucggggauug
caauuauuccccaugaacgaggaauucccaguaagugcgggucauaagcu
ugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuacc
gauuggaugguuuagugaggcccucggaucggccccgccggggugcccug
gcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucauu
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<.......<<.....<<.<<<.....>
>>.>>......>>.........<<<<...<<<<<<....>>>>>>...>>
>>....<<<<<...<......>..>>>>>............<<<.<<<<.
.....>>>>>>>...>>>>...>>..>.>>>.<<<....<<<....<<<<
<<<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>
....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>
>>>>>.........<<<....<<<<...>>>>..>>>..>...>>.>...
..<<.<<<<<<.<<<....>>>..>>>>>>..>>......<<..<.....
......>..>>.........<<<<<((......<<<<.....<<..))>>
.......>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.
<<...<<<.<<.....<<.<.<<....>>.>.>>.<<<<<<.<.......
<<...<.......>.<<<<.......>>>>...>>......>.>>>..>>
>.......<<.<..<<<<<<<............>>>>>>>.>.>>....>
>....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>
......>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>
>>...>>>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>
...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<.....
...>>>>>>>>>.>..>>>...<<..))>>...>>.....>>>.>.>.<<
<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<
<..<<<<<..<<<.<<<<<<......<<........>>..........<<
<<<.<....<<<..........<<.<<<........>>>.>>........
>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.
.....>>>...>>.>>>....<<<...<...<<<<..<<<.....<<<..
.<<<....>>>..>>>.....>>>..>>>>..>.....<<<<<.....>>
>>>........>>>....>>>.>>>...>.>>>>>>>.....>.>>>>>.
..>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<..
..>>>>.>>>....>.........>>>.>>......<...<.<<<<<...
.......>>>>>>....>.....>>>>>.....<<<<<<<<.......>>
>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<
....<<<<<<<<.<<<..<<<<.<<...<<<<<<<<<<<<<<<..>>>>>
>>>>.>.>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB8scb Structure and consequences of eRF1 glued to the ribosomal decoding center
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q5 Y7 W8 H10 P11 R12 K13 F14 G17 S18 R19 R22 C24 N26 H28 G29 L30 I31 R32 K33 Y34 R40 Q41 C42 R44 K54 L55 D56
Binding residue
(residue number reindexed from 1)		Q2 Y4 W5 H7 P8 R9 K10 F11 G14 S15 R16 R19 C21 N23 H25 G26 L27 I28 R29 K30 Y31 R37 Q38 C39 R41 K51 L52 D53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8scb, PDBe:8scb, PDBj:8scb
PDBsum8scb
PubMed38172604
UniProtG1U7M4|RS29_RABIT Small ribosomal subunit protein uS14 (Gene Name=RPS29)

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