Structure of PDB 8ipb Chain db Binding Site BS01

Receptor Information
>8ipb Chain db (length=95) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFKRRNGGRNKHGRGHVKYIRCSNCAKCCPKDKAIKRFLVRNIVEQAAVR
DVQEACVHDGYVLPKLYAKVHHCVSCAIHAHIVRVRSRENRRNRE
Ligand information
>8ipb Chain aa (length=1695) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaauccgaugauucaugauaacucgacggaucgcacg
gccuucgugccggcgacgcaucauucaaauuucugcccuaucaacuuucg
augguaggauaggggccuaccaugguggugacgggugacggagaauuagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccaauccugacacggggagguagugacaau
aaauaacaauaccgggcgcauuagugucugguaauuggaaugaguacaau
cuaaaucccuuaacgaggauccauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuuaaguuguugcaguuaaaa
agcucguaguuggaccuugggccggccggcaucgcgcuccuagcccggca
ucguuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggau
acauuagcaugggauaacaucauaggauuccgguccuauuguguuggccu
ucgggaucggaguaaugauuaauagggacagucgggggcauucguauuuc
auagucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaa
gcauuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucg
aagacgaucagauaccguccuagucucaaccauaaacgaugccgaccagg
gaucggcggauguugcuuauaggacuccgccggcaccuuaugagaaauca
aagucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggcguggagccugcgcuuaauuugacuc
aacacggggaaacuuaccagguccagacauagcaaggauugacagacuga
gagcucuuucuugauucuaugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccguuaacgaacgagaccucagccugc
uaacuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacu
auggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcc
cuuagauguucugggccgcacgcgcgcuacacugauguauucaacgagua
uauagccuuggccgacaggcccggguaaucuugggaaauuucaucgugau
ggggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaag
cgcgagucaucagcucgcguugacuacgucccugcccuuuguacacaccg
cccgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggc
gacggacgucgcgagaaguccauugaaccuuaucauuuagaggaagcaga
agucguaacaagguuuccguaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<.............<.....<..<
<<.....>>>..>......>...........<<<..<<....>>..>>>.
<...<<<<<<..................>>>>>>.....>...<<<<.<<
<<......>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>....>.
>.....<<<<<.<<..............>>.>>.>>>......<<..<..
.........>..>>.........<<<<<((......<<<<.....<<..)
)>>.......>>>>.>>>>>..>>>>>>>>>..........<.<((....
.<.<<...<<<.<<....<.<<<<..>>>>.>..................
..<<<<<<.<<.......<<...<.......>...<.......>.....>
>......>>.>>..>>>>........<<..<<<<<<<.............
..>>>>>>>..>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<.<<<.<.....>>>>>>>>>>>>..>>>...<<..))>>.
..>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<....
....>>..........<<<<<.<....<<<<<........<<.<<<....
....>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<
<<<..<<...<<<<<<<......>>>>>>>.....>>..>>>>.>>....
.<<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<..
.....<<<.<<<<....>>>>.>>>....>>........>.>>>>.....
......<<<<<<..........>>>>>>..........>>>>>>....<<
<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<
..<<.<.<<.<<.<<....<<<<<<<..<<<..<<<<..<...<<<...<
.......>...>>>...>..>>>>..>>>..>>>>>>>...>>.>>.>>.
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ipb Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T2 F3 K4 R5 R6 G9 R10 K12 H13 G14 R15 G16 H17 Y20 K32 K34 K37 R38 K70 V75 S76 I79 H80 V84 R85 V86 R87 S88 R89 R92 R95 E96
Binding residue
(residue number reindexed from 1)		T1 F2 K3 R4 R5 G8 R9 K11 H12 G13 R14 G15 H16 Y19 K31 K33 K36 R37 K69 V74 S75 I78 H79 V83 R84 V85 R86 S87 R88 R91 R94 E95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ipb, PDBe:8ipb, PDBj:8ipb
PDBsum8ipb
PubMed38267667
UniProtA0A3B6LWE1

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