Structure of PDB 4u4o Chain d4 Binding Site BS01

Receptor Information
>4u4o Chain d4 (length=134) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAE
KDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVE
KASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
Ligand information
>4u4o Chain 6 (length=1791) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccucuacaugguauaacugug
guaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagau
guauuuauuagauaaaaaaucaaugucuucggacucuuugaugauucaua
auaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauu
ucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaa
cggguaacggggaauaaggguucgauuccggagagggagccugagaaacg
gcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccuaau
ucagggagguagugacaauaaauaacgauacagggcccauucgggucuug
uaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggaggg
caagucuggugccagcagccgcgguaauuccagcuccaauagcguauauu
aaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguuggc
cgguccgauuuuuucguacuggauuuccaacggggccuuuccuucuggcu
aaccuugaguccuuguggcucuuggcgaaccaggacuuuuacuuugaaaa
aauuagaguguucaaagcaggcguauugcucgaauauauuagcauggaau
aauagaauaggacguuugguucuauuuuguugguuucuaggaccaucgua
augauuaauagggacggucgggggcaucaguauucaauugucagagguga
aauucuuggauuuauugaagacuaacuacugcgaaagcauuugccaagga
cguuuucauuaaucaagaacgaaaguuaggggaucgaagaugaucagaua
ccgucguagucuuaaccauaaacuaugccgacuagggaucgggugguguu
uuuuuaaugacccacucggcaccuuacgagaaaucaaagucuuuggguuc
uggggggaguauggucgcaaggcugaaacuuaaaggaauugacggaaggg
caccaccaggaguggagccugcggcuuaauuugacucaacacggggaaac
ucaccagguccagacacaauaaggauugacagauugagagcucuuucuug
auuuugugggugguggugcauggccguucuuaguugguggagugauuugu
cugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauaguggugc
uagcauuugcugguuauccacuucuuagagggacuaucgguuucaagccg
auggaaguuugaggcaauaacaggucugugaugcccuuagacguucuggg
ccgcacgcgcgcuacacugacggagccagcgagucuaaccuuggccgaga
ggucuugguaaucuugugaaacuccgucgugcuggggauagagcauugua
auuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuug
cguugauuacgucccugcccuuuguacacaccgcccgucgcuaguaccga
uugaauggcuuagugaggccucaggaucugcuuagagaagggggcaacuc
caucucagagcggagaauuuggacaaacuuggucauuuagaggaacuauc
guaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<............>...>>.>>......{{..
......[[[..{{..{{....[[[[..............<.....<<.<<
.......>>.>>......>.........<<<<<..<<....>>..>>>>>
....((((((......<<<<<<<<<<<....>>>..............))
)))).........<<<<..<<<.....>>>.>>>>..].]]]...}}}}.
.]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>.....
.>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<...
..>>>..>>>...............<<<<<<<<...<......>...>>>
>>.>>>......<<..<...........>..>>.........<<<<<((.
.....<<<<.....<<..))>>.......>>>>.>>>>>..))))))]]]
].........[[[{{.......{{...[[[.{{....<<<<<<.<<<..<
<<<...............>>>>......>>>.>>>>>>....<<<<<<..
..<<..<<<<.......>>>>..>>....>>>>>>...<<<<<.<<....
...<<...<.......>..<<<.....>>>....>>......>>.>>..>
>>.........[[[..((((((((....>>>>>>>>.)))))))).]]].
....}}....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<....
..>>>......>.>>>>>>..>>.......<<....>>...>>>>...>>
>>>.>>>...]]]...}}......<<<<<<<...<...<<<<........
.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<
........>>>>>>>>>>>..>>>...<<..}}>>...>>.....>>>.]
]].<<<......<<<......>>>....>>>..]]]]..<<<<<.<<<<<
<<..<<.<<<<<<..<<<.<<<<........<<........>>.......
...<<<<<......<<<<<........<<.<<<........>>>.>>...
...>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>..
.<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<
<<<<....>>>>>>...>>>>>..>>>>.>>....<<<<<<.....>>>>
>>.......>>>>>....>>>.>>>...>.>>>>>>>.......>>>>>.
.....>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....
>>>>..>>....>>.......>>>>>>>...........<<<<<<.....
.....>>>>>>..........>>>>>>....<<<<<<<<.......>>>>
>>>>......>>...>>>>>>>>>>.>>....<..<<....<<<<.<<..
..<<<<<<<<.<<<..<.<<......<<<<<<<.<<<..<........>.
...>>>.>>>>>>>......>>.>..>>>.>>>>>>>>...>>.>>>>.>
>...>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4u4o ?
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R8 T9 R10 K11 V12 K21 A33 N34 S36 K37 V47 Y48 K49 F58 F60 R61 T62 F64 G65 G66 Y89 R93 R105 Q106 R108 K109 Q110 K112 N113 K116 K117 F119 G120 T121 R124 K128 R131 R132
Binding residue
(residue number reindexed from 1)		R7 T8 R9 K10 V11 K20 A32 N33 S35 K36 V46 Y47 K48 F57 F59 R60 T61 F63 G64 G65 Y88 R92 R104 Q105 R107 K108 Q109 K111 N112 K115 K116 F118 G119 T120 R123 K127 R130 R131
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4u4o, PDBe:4u4o, PDBj:4u4o
PDBsum4u4o
PubMed25209664
UniProtP0CX31|RS24A_YEAST Small ribosomal subunit protein eS24A (Gene Name=RPS24A)

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