Structure of PDB 6hcj Chain d2 Binding Site BS01

Receptor Information
>6hcj Chain d2 (length=62) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVL
TLLESEREARRL
Ligand information
>6hcj Chain A2 (length=1740) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggucaggcggcuuuggugac
ucuagauaaccucgggccgaucgcacgcccggcggcgacgacccauucga
acgucugcccuaucaacuuucgaugguagucgccgugccuaccaugguga
ccacgggugacggggaaucaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacuccc
gacccggggagguagugacgaaaaauaacaauacaggacucuuucgaggc
ccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauugg
agggcaagucuggugccagcagccgcgguaauuccagcuccaauagcgua
uauuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcggg
cggccguccguccccugccucucggcgccccggggcccgaagcguuuacu
uugaaaaaauuagaguguucaaagcaggccgccuggauaccgcagcuagg
aauaauggaauaggaccgcgguucuauuuuguugguuuucggaacugagg
ccaugauuaagagggacggccgggggcauucguauugcgccgcuagaggu
gaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugccaag
aauguuuucauuaaucaagaacgaaagucggagguucgaagacgaucaga
uaccgucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcg
uuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugggu
uccggggggaguaugguugcaaagcugaaacuuaaaggaauugacggaag
ggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggaaa
ccucacccggcccggacacggacaggauugacagauugauagcucuuucu
cgauuccgugggugguggugcauggccguucuuaguugguggagcgauuu
gucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguuac
gcgaccccggucggcguaacuucuuagagggacaaguggcguucagccac
ccgagauugagcaauaacaggucugugaugcccuuagauguccggggcug
cacgcgcgcuacacugacuggcucagcgugugccuacccuacgccggcag
gcgcggguaacccguugaaccccauucgugauggggaucggggauugcaa
uuauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugc
guugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccgau
uggaugguuuagugaggcccucggaucggccccgccggggugcccuggcg
gagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaagucg
uaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...((((>>>>><<<.<<<<<<.....<<.........<<<.
.<<........<.....<<..........>>....>.........<<...
.....<<<.<....<<....<<.<..........<<.....<<..<....
...>..>>......>>.........<<<<...<<<<<......>>>>>..
.>>>><<...<<<<......((((.....<..<...>..>....<.....
.>..>>>>.......>>...<<<<.<<<<.>>>>>>>>..>..>>...>>
..>.>>>.<<<....<<<.....<<<<<<.........>>>>>>.>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<.<......
...>>>.>>...<<....>>.....>>.>>>.........<<<....<<<
.....>>>..>>>......>>.......<<<<<<<<..<<<....>>>..
.>>>>>.>>>......<<..<...........>..>>.........<<<<
<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>
>.>>>.........<.<.......<.<<...<<<.<<....<<<.<<<<<
.<..>.>>>>>.>>>....<......<.<.....>>....>....<<<<<
<.<........<...<.......>..<<<.>>.>...>.......>.>>>
..>>>..........<<.<<<<<<<.........))))..>>>>>>>.>>
......>>....<<<<<<......<<<<...<..<<<<<<<<...<<<..
....>>>......>>>>>>>.>.>........<<....>>...>>>>...
..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<
<<<......>>>>>>>>>>.>..>>>...<<....>>...>>.....>>>
.>.>.<<<......<.<......>.>....>>>..))))...<<<<.<<<
<<<...<<..<<<<...<<<.<<<<<<......<<........>>.....
.....<<<<<......<<<<<........<...<<........>>...>.
.....>>>>>...<..<<...<<.<<<.<.....<<<.<<<<......>>
....<<......>>....>>.>>>....<<<...<...<<<<..<<<<<<
<..<<<..>>>...>>>>>>>..>>>>..>.....<<<<<.....>>>>>
........>>>.....>..>>>.....>>.>>.>.......>>>>>...>
>.>>>>.>>>.....<<.<<<................<<<.<<<<....>
>>>.>>>..............>>>.>>.............<<<<......
....>>>>.............>>>>.....<<<<<<<<.......>>>>>
>>>......>>....>>>>>>>>>.>........<<.<..<<<<......
.<<<<<<<<.<<<..<<...<<...<<<<<.<<<<<<<<<..>>>>>>>>
>...>>>>>...>>...>>..>>>.>>>>>>>>......>>>>...>.>>
..........<<<<<<<<....>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hcj ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R20 S23 Q24 G25
Binding residue
(residue number reindexed from 1)		R14 S17 Q18 G19
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hcj, PDBe:6hcj, PDBj:6hcj
PDBsum6hcj
PubMed30293783
UniProtG1TIB4|RS28_RABIT Small ribosomal subunit protein eS28 (Gene Name=RPS28)

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