Structure of PDB 9c4g Chain d Binding Site BS01

Receptor Information
>9c4g Chain d (length=214) Species: 1747 (Cutibacterium acnes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERTVKGVLGTKLGMTQLWDEHNRLVPVTVIQAGPCVVTQVRTPETDGYSA
VQLGYGAVKAKNVTKPEAGHFEKAGVTPRRHLVELRTADASEYTLGQEIA
ADVFSESDFVDVTGTSKGKGTAGVMKRHGFGGLRATHGVHRKHRSPGSIG
GCSTPGKVIKGLRMAGRMGVERVTVQNLQVHSVDAERGIMLVRGAVPGPK
GSLLVVRSAAKKAA
Ligand information
>9c4g Chain a (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaaguuguguagugcgaucgguggaugccuuggcaccaagagccgauga
aggacguugugaccugcgauaagcccuggggaguuggugagcgagcugug
auccggggguguccgaauggggaaaccuggaauguccggaguaguguccg
guggcccugcccugaauguauaggggugugggugguaacgcggggaagug
aaacaucuuaguacccguaggaagagaaaacaagugugauuccgugagua
guggcgagcgaaagcggaggaggcuaaaccgugugugugucagguguugc
augugcgggguugugggggccuugugguucugcugccgcaggauuggcca
gugagaaauguugcgugaaggugaagcgucugggaaggcguaccggagug
ggugagaguccuguaacuguaagcguggcacuggugugggguugccccga
guagcgugggacucguggaauuucgcgugaaucuggcgggaccacccguc
aagccuaaauacuccuuggugaccgauaguggaugaguaccgugagggaa
gggugaaaaguaccccgggaggggagugaaagaguuccugaaaccggucg
caugcaagccgucagagccuguguggugauggcgugccuuuugaagaaug
agccugcgaguuagugaugcguggcgagguuaacccguggugggggaguc
guagcgaaagcgaguccgauaagggcgugagucgcguguucuagacccga
agcggugugaucuauccauggccaggaugaagcgucgguaagacgucgug
gagguccgaacccacuucaguugaaaauggaggggaugaguuguggauag
gggugaaaggccaaucaaacaccgugauagcugguucuccccgaaaugca
uuuaggugcagcguugcgugguucuuguuggagguagagcacuggauggu
cuagggggcuuaucggcuuaccgaaaucagccaaacuccgaaugcuggca
aguguagcguggcagugagacggcgggugauaagcuucgucgucgagagg
gaaacagcccagaucaucagcuaaggccccuaaguggugacucaguggga
aaggauguggaguugcguagacaaccaggagguuggcuuggaagcagcca
uccuugaaagagugcguaauagcucacuggucaagugauuccgcgccgau
aauguagcggggcuuaaguuauccgccgaagcuguggcaaccuguguggu
uggguaggggagcgucgugucaguggugaagcugccgggugacugugugg
uggaguugaugcgagugagaaugcaggcaugaguagcgugugacgggugg
gaaucccguccgccgauuauccaaggguuccagggucaaguuugucugcc
cugggugagucggguccuaaggcgaggccgacaggcguagucgaugggua
accaguugauauucugguaccggcuugucaccgcaagcugcggagggacg
cagugagguagcucauccccggugaugguuguccggggcuaagugugugg
acugucugguagguaaauccgcugggcgugaagguugaggcaugaugggg
agcccaugguugugggugagugagugauccuguacugucgagaaaagcuu
cgugagcgagguggcggguccgcccguacccuaaaccgacacugguggau
agguagaguauaccgaggcgaucgagugaaucguggugaaggaacucggc
aaaaugcccccguaacuuugggauaagggggaccugagcugucgugcacc
cgugcggugugguggcggugaggggcgcagaguccagggggaaacgacug
uuuaccaaaaacacagguccgugcgaagucguaagacgauguauacggac
ugacuccugcccggugcuggaagguuaaggggaacugugaguguaugcgu
agcggugaacuuaagccccaguaaacggcggugguaacuauaaccauccu
aagguagcgaaauuccuugucggguaaguuccgaccugcacgaauggagu
aacgauuucccuacugucuccaccaugaacucggugaaauugcauuacga
guaaagaugcucguuacgcgcagcaggacggaaagaccccgggaccuuua
cuauaguuugguauuggugauugggacgguuuucugauuguucugguuau
cucacuguggaccgugauccgguucaaggacagugccugauggguaguuu
gacuggggcggucgccuccuaaaggguaacggaggcgcccaaagguuccc
ucagccugguugguaaucagguggugaguguaagugcacaagggggcuug
acugugagacugacaggucgagcagggacgaaagucgggacuagugaucu
gacgguggcuuguggaugcgccgucacucaacggauaaaagguaccccgg
ggauaacaggcugaucuugcccgagcgcucauagcgacggcaugguuugg
caccucgaugucggcucgucgcauccuggggcuggagucggucccaaggg
uugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucg
ugagacaguucggucccuauccgcugcgcgcggaggaaucuugagaaggg
cugucuuuaguacgagaggaccgagacggacugaccucuggugugccagu
uguucugccaagagcauggcugguuggcuacgucggguugugauaaccgc
ugaaagcaucuaagcgggaagcacgcuucaagauaaggguucccacagga
guguuccugguaagguccccgagagaugaucggguugauaggccagacgu
ggacgcaucguaagguguggagcugacugguacuaauagaccgaggacuu
uca
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<....>>......>>>>>.>.........<<<..>>>..<<<<<<.....
<<.....>>....>>>>>>..<<<....<<<<..................
....>>>>......<<<<<<<<<......<<<<....>>>>.........
.........<<..<<<...<<<...<<<<<......>>>>>((......<
<<.....))>>>...>>>......>>>..>>......>>>>>..>>>>..
...<<<<<<<<.........>>>>>>>>.......<<<<..<<<<>>>>.
..>>>......]].>>>>>>>.]]...............<<....>>...
.]].........<<<<....>>>>..................>>>>>>>>
>>>.......<<<<..<<<.....>>>..>>>>...<.<........>.>
.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>....>>>>>>>>>>>>>..<<.<.
.<<<<<<<.....<<<<<<<<<..<<<....<<<.<<......>>.>>>.
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.<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<<
<....>>>>><<<<<<<<<....<<<<<<<<.....<<<...<<<.<<<<
...<<.<<<<....>>>>..>>...>>>>.>>>..>>.>.....>>>>>>
>>....>>>>>>>.>>..<<<<<<<<<........>>>>>>>>>....<<
<......>>>...<<<<.<<<...<<<(((.....<<<<<<.........
..<<..<<<<<<<<<........<<<<<.<<...<<<.........>>>.
..>>.........<<......>>...>>>>>....>>>>>>>>>.>>...
........)))......>>>>>>.>>>...>>>>>>><<<<<.....>>>
>>....>>>>>>..<<<<<<<<<.......<<<<<<<<....>>>.>>>>
>....>>>>>>>>>........>>>>>><......<<....<<<<<<...
....>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>
>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...
<<<<<........>>>>>))<<<.<<..<..<....<<<<<<<<<....<
<<<..<<<..<<<<<.<<<<<<...((((...>>>>>><<..<<<<...<
<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>...>>>>...>>..
..<<.........>>.....>>>>>...>>>...>>>>.........>>>
>>>.>>>...>..>..>>.>>>>>>>..>>.....<<......>>>>>>>
.<<<<.....>>>>..>>>>..<<<<<...<<<<<<<<.<<.........
<.....<<<<<.....<..>......>>>>>.<<<..<<<<<<<.....<
......>.....>>>>>>>..>>>.............<<<<<<<<<..<<
<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>
>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<..<<....>>..
.>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>>>
..>>.>>>>>>>..>..>>.>>>>>>>>>>>>>>>.....>.((..<<<<
<......))>>>>>..<<<<<<<<.(((.[[......<<<<<<<<<<..<
<<<<.<<<.<<<<<.<<<<<<<<<<<<<<........>>>>>>>>>>>>>
>...<<.<<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..
<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<
...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>..
.<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<
<<<<<<.((..>>>>..))>>>>>>>.............>>>>..>>>>>
>.......<<<<.<.<.<<<<<..<<.......>>>..>>>>.>...>>>
>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>
.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<.
...>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..
<<<<<<<...............>>>>>>>.<<<<<...<<<<..<<<<<<
<<<<<<))))>>>>>>..>>>>>>..>>>>.>>>>>..<<<<....<<<<
<...........>>>>>....>>>>>>>>.......>>>>>>>..<<<<<
....>>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<
....<<<<<....>>>>>...>>...>>>>>.>>>...>>>>......>>
>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9c4g Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		K14 M17 Q19 P29 Q42 R44 T48 D49 Y51 K62 K64 N65 T67 K68 P69 G72 H73 K76 R83 L85 E87 R89 S119 K120 G121 K122 G123 T124 G126 K129 F133 G134 G135 L136 R137 A138 T139 H140 G141 H143 R144 K145 H146 R147 P149 G150 S151 I152 G153 G154 C155 S156 T157 P158 G159 K160 V161 I162 K163 G164 L165 R166 M167 A168 R170 R175 V176 T177 Q179 N180 A198 V199 P200 G201 P202 K214
Binding residue
(residue number reindexed from 1)		K11 M14 Q16 P26 Q39 R41 T45 D46 Y48 K59 K61 N62 T64 K65 P66 G69 H70 K73 R80 L82 E84 R86 S116 K117 G118 K119 G120 T121 G123 K126 F130 G131 G132 L133 R134 A135 T136 H137 G138 H140 R141 K142 H143 R144 P146 G147 S148 I149 G150 G151 C152 S153 T154 P155 G156 K157 V158 I159 K160 G161 L162 R163 M164 A165 R167 R172 V173 T174 Q176 N177 A195 V196 P197 G198 P199 K211
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