Structure of PDB 8ovj Chain d Binding Site BS01

Receptor Information
>8ovj Chain d (length=93) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTINAKLQLVMKSGKYVLGTQQALTTLRQGRSKLVVIANNCPPIRRAEVE
YYCTLSKTPIHHYSGNNLDLGTACGKHFRTCVLSVTNVGDSDI
Ligand information
>8ovj Chain 3 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugguaaugcggccagguaacaaaucaauccucccacggugagcuuucuu
uucaccauaauccaccuugggccuuuuuacucucgcguuguucggagcgg
gggcucaagauugaaaaaugcauugugaguucugcgcuaaagcaaaaacc
uggggu
<<<....>>>..<<<<<<.......<<...<<<.<<.<<<<<<.......
>>>>>><...<<.<.<<<<<<<<<<<.......<<.......>>....>>
>>>>>>>>>.>.>>....>....>>.>>>...>>.............>>>
>>>...
Receptor-Ligand Complex Structure
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PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
Y25 G28 T29 Q30 Q31 R54 H86 F87 R88
Binding residue
(residue number reindexed from 1)
Y16 G19 T20 Q21 Q22 R45 H77 F78 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtE9AEK1

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