Structure of PDB 7syp Chain d Binding Site BS01

Receptor Information
>7syp Chain d (length=67) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVRE
GDVLTLLESEREARRLR
Ligand information
>7syp Chain 2 (length=1680) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau
gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc
ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua
gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa
caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa
uccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcuc
guaguuggaucuugcucggcgccggcccgaagcguuuacuuugaaaaaau
uagaguguucaaagcaggccgccuggauaccgcagcuaggaauaauggaa
uaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauuaa
gagggacggccgggggcauucguauugcgccgcuagaggugaaauucuug
gaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuuca
uuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucgua
guuccgaccauaaacgaugccgaccggcgaugcggcggcguuauucccau
gacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggggga
guaugguugcaaagcugaaacuuaaaggaauuuggcgaagggcaccacca
ggaguggagccugcggcuuaauuugacucaacacgggaaaccucacccgg
cccggacacggacaggauugacagauugauagcucuuucucgauuccgug
ggugguggugcauggccguucuuaguugguggagcgauuugucugguuaa
uuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgaccccgg
ucggcguaacuucuuagagggacaaguggcguucagccacccgagauuga
gcaauaacaggucugugaugcccuuagauguccggggcugcacgcgcgcu
acacugacuggcucagcgugugccuacccuacgccggcaggcgcggguaa
cccguugaaccccauucgugauggggaucggggauugcaauuauucccca
ugaacgaggaauucccaguaagugcgggucauaagcuugcguugauuaag
ucccugcccuuuguacacaccgcccgucgcuacuaccgauuggaugguuu
agugaggcccucggaucggccccgccggggugcccuggcggagcgcugag
aagacggucgaacuugacuaucuagaggaaguaaaagucguaacaagguu
uccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<.........<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<......<<....<<<<.........<<.....<<.<<.....
..>>.>>......>>.........<<<<...<<<<<<....>>>>>>...
>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<
...>>>>>>>..>.>>>...>>....>>>.<<<....<<<....<<<<<<
<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<<..>>>.>...>>>
>>>.........<<<...<<<<.....>>>.>>>>......>>.>.....
<<<..<<<..<<<....>>>...>>>...>>>......<<..<.......
....>..>>.........<<<<<((......<<<<.....<<..))>>..
.....>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<
...<.<.<<....<<<<<<.<<..>>>>>>.>>..<<<<<<.<.......
<<...<.......>.<<<<.>>>>...>>......>.>>>..>>>.....
...<.<<.<<<<<<<...............>>>>>>>.>>.>....>>..
..<<<<<<..<...<<<<..<<<.<<<<<<<<...<<<......>>>...
...>>>>>>>>.>>>.......<<....>>...>>>>..>..>>>.>>>.
..>.>...>>.>....<<<<<<....<...<<<<.<.....>.>>>>...
>.>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<........
>>>>>>>>>.>..>>>...<<..))>>...>>.....>>>.>.>.<<<..
....<<<......>>>....>>>..)))).]..<...<<<<<<<..<<..
<<<<<.<<<<.<<<<<<......<<........>>..........<<<<<
......<<<<<<........<..<<........>>.>.......>>>>>>
.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<....
..>>>...>>.>>>....<<<...<...<<<<..<<<<<<<<<<<<..>>
>>.>>>>>>>>..>>>>..>.....<<<<<.....>>>>>........>>
>....>>>.>>>.....>>>>>>>>......>>>>>...>>.>>>>.>>>
.>...<<.<<<........<.......<<<.<<<<....>>>>.>>>...
.>.........>>>.>>......<.....<<<<<..........>>>>>.
....>.....>>>>>.....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>..>.......<..<<.<..<<<<.<<....<<<<<<<<.
<<<..<<<<.<<...<<<<<..<<..............>>....>>>>>.
..>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<
<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7syp Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R20 S23 Q24 P49
Binding residue
(residue number reindexed from 1)		R18 S21 Q22 P47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7syp, PDBe:7syp, PDBj:7syp
PDBsum7syp
PubMed35822879
UniProtG1TIB4|RS28_RABIT Small ribosomal subunit protein eS28 (Gene Name=RPS28)

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