Structure of PDB 6s13 Chain d Binding Site BS01 |
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| >6s13 Chain a (length=1539)
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auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau |
...........<.<<<<......<<<..<<<<.<..<<<<<<<.....<<
<.<<....<<..<<..<<<......................>>>..>>>>
.......<<........<<<<<<...<<...<<<<..<..........<<
..<<....>>..>>....................................
........................>..>>>>..>>.>>>>>>.<<<....
<<<....<<<<<<.......>>>>>>..>>>......>>>..<<<<<<<.
.....>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>....>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>..........................................<<
...........<<<<<........>>>>>............>>.......
......<.((.....<<<<.....<<..))>>.......>>>>..>....
>.>>>>.>>>..........<<<((.....<<<....<<<.<<<<<<..<
<....<<<.......<<<<<<.....>>>>>>.....>>>......>>.>
>>>>>...<<..<.<<....<.<<<<...............<<.......
.>>.........................<<....>>.>>>>>....>>.>
...>>...>>>....>>>....<..<<.........<<<..........>
.>>......>>..>..........<<<<<<..<<..<<<<<<<<......
>>>>>>>>..>>...<...)).>.....>>>>>>.>>>..<<.......<
<<....>>>.....>>...>>>>.>.<....<<<<<<<.....<<<<<..
<<<<<...........<<........>>..........<<<<<<<.....
.<<<<.......<<<<<....>>>>>.....<<.....>>......>>.>
>..<<.<<<...<<<.........<<<<<.<<<....>>>...<<<....
..>>>....>>>>>......<<..<....<........<<......>>..
.....>...>......<<<<.......>>>>.........>>........
.......>>>.>>>>>....>>>>>>>.........>>>>>.......<<
<<<.....<<<..........................>>>.....>>>>>
.............<.<..<..........>..>.>..........>>>>>
......<<<<<<.........>>>>>>............>>>>>>>....
>.............<<<<.<<.......<<..<<<<....<.<<<<..<<
..............>>.>>>>>....>>>>..>>.......>>.>>>>..
.............<<<<<............>>>>>.... |
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| PDB | 6s13 Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. |
| Resolution | 3.58 Å |
Binding residue
(original residue number in PDB) | R5 W9 K10 R13 T22 E27 K28 P33 G34 Q35 H36 Q40 K42 Y47 L51 R52 R58 Y59 M63 T64 E65 R66 Q67 Y99 Q109 R111 Q112 L113 N115 H116 H118 L120 R125 I128 Y131 R142 K144 S145 L148 N149 |
Binding residue
(residue number reindexed from 1) | R3 W7 K8 R11 T20 E25 K26 P31 G32 Q33 H34 Q38 K40 Y45 L49 R50 R56 Y57 M61 T62 E63 R64 Q65 Y97 Q107 R109 Q110 L111 N113 H114 H116 L118 R123 I126 Y129 R140 K142 S143 L146 N147 |
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| Enzyme Commision number |
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