Structure of PDB 6j6n Chain d Binding Site BS01

Receptor Information
>6j6n Chain d (length=566) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DILDLEELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRAR
SIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTLPRVDKL
WYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQKNWNGV
REIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNL
QIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSNQLLKAGLL
DFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESFP
KQIMQTFEKAIVDSRKELSKNVQWKRYIYLWMRYVELELENSLLEEEFQR
LIDDIIPHKHFTKIWLMYAKFLIRHDDVKARKILGKAIGLCPKAKTELEV
KLKEFDRVRKIYKFIEFQPSDLQIWSLEENLGDWDRVRGIYTALDENSDF
LTKEAKIVLQKYITFETESQERKLYRRYLELNQYSPQSWYQTSTPTEQQL
LDLAKLQVDEDIEFEITDENKLEARKFEEAIVFFKEKDDKQGRLSILEAD
YEETYGTELDQETVKK
Ligand information
>6j6n Chain E (length=103) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
uua
<<<<<<<<<<.....>>>>>>>>>>.........................
............<<<..<<<.....>>>...>>>................
...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j6n Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.86 Å
Binding residue
(original residue number in PDB)		E53 Y57 K59 R60 Q67 R70 I99 P100 R104 K134
Binding residue
(residue number reindexed from 1)		E18 Y22 K24 R25 Q32 R35 I64 P65 R69 K99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000354 cis assembly of pre-catalytic spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0006270 DNA replication initiation
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000785 chromatin
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071004 U2-type prespliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071008 U2-type post-mRNA release spliceosomal complex
GO:0071014 post-mRNA release spliceosomal complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6n, PDBe:6j6n, PDBj:6j6n
PDBsum6j6n
PubMed30879786
UniProtQ12309|CLF1_YEAST Pre-mRNA-splicing factor CLF1 (Gene Name=CLF1)

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