Structure of PDB 5zeb Chain d Binding Site BS01

Receptor Information
>5zeb Chain d (length=200) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARYTGPATRKSRRLGVDLVGGDQSFEKRPYPPGQHGRARIKESEYRQQLQ
EKQKARFSYGVMEKQFRRYYEEANRQPGKTGDNLLRILESRLDNVVYRAG
LARTRRMARQLVSHGHFLVNGVKVDIPSYRVSQYDIIDVKEKSLNTLPFQ
IARETAGERPIPSWLQVVGERQRILVHQLPERAQIDVPLTEQLIVELYSK
Ligand information
>5zeb Chain a (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac
augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg
gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa
acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg
aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg
ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc
ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu
ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag
ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa
gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc
gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc
ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg
gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu
ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga
aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag
cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua
gguguggguuuccuugggauccgugccguagcuaacgcauuaaguacccc
gccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgggggc
ccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaagaacc
uuaccuggguuugacaugcacaggacgccggcagagaugucgguucccuu
guggccugugugcagguggugcauggcugucgucagcucgugucgugaga
uguuggguuaagucccgcaacgagcgcaacccuugucucauguugccagc
acguuaugguggggacucgugagagacugccggggucaacucggaggaag
guggggaugacgucaagucaucaugccccuuauguccagggcuucacaca
ugcuacaauggccgguacaaagggcugcgaugccgugagguggagcgaau
ccuuucaaagccggucucaguucggaucggggucugcaacucgaccccgu
gaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaauacg
uucccgggccuuguacacaccgcccgucacgucaugaaagucgguaacac
ccgaagccgguggccuaacccuuguggagggagccgucgaaggugggauc
ggcgauugggacgaagucguaacaagguagccguaccggaaggugcggcu
ggauca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>......
<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<....
..>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>.
...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<
<......<<<<....>>>>.....>>>>...<.<<<<<......<<....
>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>>
.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<
<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>>
>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<<
<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<..
..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<
<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<..
<<<<<<<<<<<<...>>>>>>>>>>>>...<<..))>>.....>>>>>>.
>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.<<...
..>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>
>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<<..<
<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....
>>>......>>>>>>>......<....<<<<<<<........>>>>>>>.
...>.....>>>>>>....<<<<<<<..........>>>>>>>......>
>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<..<<<
<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>..>>>
>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>
......
Receptor-Ligand Complex Structure
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PDB5zeb Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
A2 R3 Y4 R10 R14 K28 R29 Y31 P33 G34 H36 Y46 R47 L50 Q54 R57 M63 E64 K65 Q66 R68 R69 R76 R104 T105 M108 R110 Q111 S114 H115 H117 V125 D126 I127 P128 S129 Y130 T147 P149 E197 S200 K201
Binding residue
(residue number reindexed from 1)
A1 R2 Y3 R9 R13 K27 R28 Y30 P32 G33 H35 Y45 R46 L49 Q53 R56 M62 E63 K64 Q65 R67 R68 R75 R103 T104 M107 R109 Q110 S113 H114 H116 V124 D125 I126 P127 S128 Y129 T146 P148 E196 S199 K200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5zeb, PDBe:5zeb, PDBj:5zeb
PDBsum5zeb
PubMed30206241
UniProtA0QSL7|RS4_MYCS2 Small ribosomal subunit protein uS4 (Gene Name=rpsD)

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