Structure of PDB 5ndg Chain c9 Binding Site BS01 |
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| >5ndg Chain 6 (length=1700)
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uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauua
aaucaguuaucguuuauuugauaguuccucuacaugguauaacuguggua
auucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagaugua
uuuauuagauaaaaaaucaaugucuucggacucuuugaugauucauaaua
acuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucu
gcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgg
guaacggggaauaaggguucgauuccggagagggagccugagaaacggcu
accacauccaaggaaggcagcaggcgcgcaaauuacccaauccuaauuca
gggagguagugacaauaaauaacgauacagggucuuguaauuggaaugag
uacaauguaaauaccuuaacgaggaacaauuggagggcaagucuggugcc
agcagccgcgguaauuccagcuccaauagcguauauuaaaguuguugcag
uuaaaaagcucguaguugaacuuugggcccgguuaacggggccuuuccuu
cuggcuaaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcag
gcguauugcucgaauauauuagcauggaauaauagaauaggacguuuggu
ucuauuuuguugguuucuaggaccaucguaaugauuaauagggacggucg
ggggcaucaguauucaauugucagaggugaaauucuuggauuuauugaag
acuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaagaac
gaaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccaua
aacuaugccgacuagggaucgggugguguuuuuuuaaugacccacucggc
accuuacgagaaaucaaagucuuuggguucuggggggaguauggucgcaa
ggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccu
gcggcuuaauuugacucaacacggggaaacucaccagguccagacacaau
aaggauugacagauugagagcucuuucuugauuuugugggugguggugca
uggccguucuuaguugguggagugauuugucugcuuaauugcgauaacga
acgagaccuuaaccuacuaaauaguggugcuagcauuugcugguuaucca
cuucuuagagggacuaucgguuucaagccgauggaaguuugaggcaauaa
caggucugugaugcccuuagacguucugggccgcacgcgcgcuacacuga
cggagccagcgagucuaaccuuggccgagaggucuugguaaucuugugaa
acuccgucgugcuggggauagagcauuguaauuauugcucuucaacgagg
aauuccuaguaagcgcaagucaucagcuugcguugauuacgucccugccc
uuuguacacaccgcccgucgcuaguaccgauugaauggcuuagugaggcc
ucaggaucugcagagcggagaauuuggacaaacuuggucauuuagaggaa
cuaaaagucguaacaagguuuccguaggugaaccugcggaaggaucauua |
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<.......>>...>>.>>......{{.....
...[[[..{{..{{....[[[...............<.....<<.<<<..
...>>>.>>......>.........<<<<<..<......>..>>>>>...
.((((((......<<<<<<<<<<<<..>>>>..............)))))
).........<<<<..<<<.....>>>.>>>>....]]]...}}}}..]]
].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>
>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........>>>
.>>.<.<<....>>.>...]]]]]].........<<<....<<<.....>
>>..>>>...............<<<<<<<<....>>>>>.>>>......<
<..<...........>..>>.........<<<<<((......<<<<....
.<<..))>>.......>>>>.>>>>>..))))))]]]].........[[[
{{.......{{...[[[.{{....<<<<<<.<<..>>.>>>>>>....<<
<<<<.....>>>>>>...<<<<<.<<.......<<...<.......>..<
<<.....>>>....>>......>>.>>..>>>.........[[[..((((
((((....>>>>>>>>.)))))))).]]].....}}....<<<<<<.<<.
..<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>.
.>>.......<<....>>...>>>>...>>>>>.>>>...]]]...}}..
....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>....
......<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>>>>.
.>>>...<<..}}>>...>>.....>>>.]]].<<<......<<<.....
.>>>....>>>..]]]]..<<<<<.<<<<<<<..<<.<<<<<<..<<<.<
<<<<<......<<........>>..........<<<<<.<....<<<<<.
.......<<.<<<........>>>.>>......>>>>>...<<.<<<..<
<.<<<<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>
>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>>...>>>
>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>....>>
>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<
<<<<<......<<.....<<..<<<<....>>>>..>>....>>......
.>>>>>>>...........<<<<<<..........>>>>>>.........
.>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>
>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<.<<
..<...<<<<.....>>>>...>..>>.>..>>>.>>>>>>>>...>>.>
>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>......... |
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| PDB | 5ndg Aminoglycoside interactions and impacts on the eukaryotic ribosome. |
| Resolution | 3.7 Å |
Binding residue
(original residue number in PDB) | P2 G3 V4 R7 A11 Q12 I15 Y33 V37 K38 T39 S41 N43 E44 M45 P47 Q48 R57 S60 R63 H64 R68 K69 G72 V73 G74 K75 K78 L79 G82 A83 K84 R86 G87 V88 R89 P90 Y91 H93 S97 G98 S99 R102 Q106 K119 R122 E126 Q129 R130 D133 |
Binding residue
(residue number reindexed from 1) | P1 G2 V3 R6 A10 Q11 I14 Y32 V36 K37 T38 S40 N42 E43 M44 P46 Q47 R56 S59 R62 H63 R67 K68 G71 V72 G73 K74 K77 L78 G81 A82 K83 R85 G86 V87 R88 P89 Y90 H92 S96 G97 S98 R101 Q105 K118 R121 E125 Q128 R129 D132 |
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