Structure of PDB 6hcq Chain c2 Binding Site BS01

Receptor Information
>6hcq Chain c2 (length=83) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQ
TVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
Ligand information
>6hcq Chain A2 (length=1740) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggucaggcggcuuuggugac
ucuagauaaccucgggccgaucgcacgcccggcggcgacgacccauucga
acgucugcccuaucaacuuucgaugguagucgccgugccuaccaugguga
ccacgggugacggggaaucaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacuccc
gacccggggagguagugacgaaaaauaacaauacaggacucuuucgaggc
ccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauugg
agggcaagucuggugccagcagccgcgguaauuccagcuccaauagcgua
uauuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcggg
cggccguccguccccugccucucggcgccccggggcccgaagcguuuacu
uugaaaaaauuagaguguucaaagcaggccgccuggauaccgcagcuagg
aauaauggaauaggaccgcgguucuauuuuguugguuuucggaacugagg
ccaugauuaagagggacggccgggggcauucguauugcgccgcuagaggu
gaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugccaag
aauguuuucauuaaucaagaacgaaagucggagguucgaagacgaucaga
uaccgucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcg
uuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugggu
uccggggggaguaugguugcaaagcugaaacuuaaaggaauugacggaag
ggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggaaa
ccucacccggcccggacacggacaggauugacagauugauagcucuuucu
cgauuccgugggugguggugcauggccguucuuaguugguggagcgauuu
gucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguuac
gcgaccccggucggcguaacuucuuagagggacaaguggcguucagccac
ccgagauugagcaauaacaggucugugaugcccuuagauguccggggcug
cacgcgcgcuacacugacuggcucagcgugugccuacccuacgccggcag
gcgcggguaacccguugaaccccauucgugauggggaucggggauugcaa
uuauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugc
guugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccgau
uggaugguuuagugaggcccucggaucggccccgccggggugcccuggcg
gagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaagucg
uaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...((((>>>>><<<.<<<<<<.....<<.........<<<.
.<<........<.....<<..........>>....>.........<<...
.....<<<.<....<<....<<.<..........<<.....<<..<....
...>..>>......>>.........<<<<...<<<<<......>>>>>..
.>>>><<...<<<<......((((.....<..<...>..>....<.....
.>..>>>>.......>>...<<<<.<<<<.>>>>>>>>..>..>>...>>
..>.>>>.<<<....<<<.....<<<<<<.........>>>>>>.>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<.<......
...>>>.>>...<<....>>.....>>.>>>.........<<<....<<<
.....>>>..>>>......>>.......<<<<<<<<..<<<....>>>..
.>>>>>.>>>......<<..<...........>..>>.........<<<<
<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>
>.>>>.........<.<.......<.<<...<<<.<<....<<<.<<<<<
.<..>.>>>>>.>>>....<......<.<.....>>....>....<<<<<
<.<........<...<.......>..<<<.>>.>...>.......>.>>>
..>>>..........<<.<<<<<<<.........))))..>>>>>>>.>>
......>>....<<<<<<......<<<<...<..<<<<<<<<...<<<..
....>>>......>>>>>>>.>.>........<<....>>...>>>>...
..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<
<<<......>>>>>>>>>>.>..>>>...<<....>>...>>.....>>>
.>.>.<<<......<.<......>.>....>>>..))))...<<<<.<<<
<<<...<<..<<<<...<<<.<<<<<<......<<........>>.....
.....<<<<<......<<<<<........<...<<........>>...>.
.....>>>>>...<..<<...<<.<<<.<.....<<<.<<<<......>>
....<<......>>....>>.>>>....<<<...<...<<<<..<<<<<<
<..<<<..>>>...>>>>>>>..>>>>..>.....<<<<<.....>>>>>
........>>>.....>..>>>.....>>.>>.>.......>>>>>...>
>.>>>>.>>>.....<<.<<<................<<<.<<<<....>
>>>.>>>..............>>>.>>.............<<<<......
....>>>>.............>>>>.....<<<<<<<<.......>>>>>
>>>......>>....>>>>>>>>>.>........<<.<..<<<<......
.<<<<<<<<.<<<..<<...<<...<<<<<.<<<<<<<<<..>>>>>>>>
>...>>>>>...>>...>>..>>>.>>>>>>>>......>>>>...>.>>
..........<<<<<<<<....>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hcq ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Resolution6.5 Å
Binding residue
(original residue number in PDB)		R17 H19 K20 K21 K22 P28 Q51 T67 G69 K70 R72
Binding residue
(residue number reindexed from 1)		R16 H18 K19 K20 K21 P27 Q50 T66 G68 K69 R71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0046872 metal ion binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hcq, PDBe:6hcq, PDBj:6hcq
PDBsum6hcq
PubMed30293783
UniProtG1TZ76|RS27_RABIT Small ribosomal subunit protein eS27 (Gene Name=RPS27)

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