Structure of PDB 8cq7 Chain c Binding Site BS01

Receptor Information
>8cq7 Chain c (length=98) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKKRASNGRNKKGRGHVKPVRCLNCARCVPKDKAIKRVTIRNMVEAAAVR
DLSEASVYAEYALPKLYNKLHYCVSCAIHARIVRVRSRTDRKIRTPPQ
Ligand information
>8cq7 Chain B (length=1756) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccgcguacuggacccagccgagccuuuccuucuggguagccauuu
auggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuaugguu
cuauuuuguugguuucuaggaccaucguaaugauuaauagggacggucgg
ggguaucaguauucaguugucagaggugaaauucuuggauuuacugaaga
cuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaagaacg
aaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccauaa
acuaugccgacuagggaucgguuguuguucuuuuauugacgcaaucggca
ccuuacgagaaaucaaagucuuuggguucuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcuuaauuugacucaacacggggaaacucaccagguccagacacaaua
aggauugacagauugagagcucuuucuugauuuugugggugguggugcau
ggccguucuuaguugguggagugauuugucugcuuaauugcgauaacgaa
cgagaccuuaaccuacuaaauagugcugcuagcauuugcugguauaguca
cuucuuagagggacuaucgauuucaagucgauggaaguuugaggcaauaa
caggucugugaugcccuuagacguucugggccgcacgcgcgcuacacuga
cggagccagcgaguauaagccuuggccgagaggucugggaaaucuuguga
aacuccgucgugcuggggauagagcauuguaauuguugcucuucaacgag
gaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccugcc
cuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagugaggc
cuccggauugguuuauucuggaaccgagaagcuggucaaacuuggucauu
uagaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaag
gaucau
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<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......{.((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
....................>>>>>>>>>>.....<<<<...........
.........>>>>....<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<<<<<<
<<......)))).}...>>>>>>>>>>>.....>>....<<<<<<.<<..
.<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..
>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>.
...<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.....
.....<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>>>..
>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<....>
>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<
<<<<......<<........>>..........<<<<<.<....<<<<<..
......<<.<<<........>>>.>>......>>>>>...<<.<<<..<<
.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>>.>>
>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>
>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.....>
>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<
<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.....
..>>>>>>>......<....<<<<<<..........>>>>>>....>...
..>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>
>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<
<..<...<<<<<<........>>>>>>...>..>>>>..>>>.>>>>>>>
>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.2 Å
Binding residue
(original residue number in PDB)
P2 K3 K4 R5 A6 S7 N8 G9 R10 N11 K12 K13 G14 R15 G16 H17 K19 R28 K32 K34 R38 K70 V75 S76 I79 H80 R82 V84 R85 V86 R87 S88 R89 R92 R95 P97 P98
Binding residue
(residue number reindexed from 1)
P1 K2 K3 R4 A5 S6 N7 G8 R9 N10 K11 K12 G13 R14 G15 H16 K18 R27 K31 K33 R37 K69 V74 S75 I78 H79 R81 V83 R84 V85 R86 S87 R88 R91 R94 P96 P97
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