Structure of PDB 8byv Chain c Binding Site BS01

Receptor Information

>8byv Chain c (length=204) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325)

GQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASV
SHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHIN
VIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQ
VSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWI
YRGE

Ligand information

>8byv Chain a (length=1533)

ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuaggggguuucccgc
cccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacgac
cgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugga
gcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugaca
uccuuugacaacucuagagauagagccuuccccuucgggggacaaaguga
cagguggugcaugguugucgucagcucgugucgugagauguuggguuaag
ucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguugggc
acucuaaguugacugccggugacaaaccggaggaagguggggaugacguc
aaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggaca
auacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguuguu
cucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgcu
aguaaucguagaucagcaugcuacggugaauacguucccgggucuuguac
acacccgucacaccacgagaguuuguaacacccgaagccgguggaguaac
cuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaagucg
gguagccguaucggaaggugcggcuggaucacc

...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<<....<<<........>>>....>>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<<<<<<<....>>>>>>>>>
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
..........<<............>>.............>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<<<.....>>
>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<
<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<..<<<<<..<
<<<<<<<........<<........>>..........<<<<<<<......
<<<<<......<<<<<....>>>>>.....<<<....>>>....>>>.>>
.<<<.<<<...<<<<<<......<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>.....<<<<.<<<<<<...<<<..<<......>>>>>
....>>>>>>.....<<<<<.....>>>>>........>>>>.......>
.>>>...>>.>>>>>>...>>>>>>>......>>>>>>>>.....<<<<<
<<.....<<<..<<...<<<....>>>...>>....>>>.....>>>>>>
>......<....<<<<<<<........>>>>>>>....>.....>>>>>.
....<<<<<<<.........>>>>>>>......>....>>>>>>>>>>.>
>....<<...<<<<.<<<...<<<<<..<<<<....<.<<<<..<<<..<
<<...>>>.>>>.>>>>.>...>>>>..>>>>>...>>>.>>>>....>>
...<<<<<<<<<....>>>>>>>>>........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8byv Structural characteristic of RbfA from S. aureus
• Resolution: 2.89 Å
• Binding residue (original residue number in PDB): G2 Q3 K4 I5 K26 S153 G154 R155 D160 I161 A162 T171 V172 L174 H175 T176 L177 R178 H185 E187 T191 G193 K194 G196 K198
• Binding residue (residue number reindexed from 1): G1 Q2 K3 I4 K25 S152 G153 R154 D159 I160 A161 T170 V171 L173 H174 T175 L176 R177 H184 E186 T190 G192 K193 G195 K197

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8byv, PDBe:8byv, PDBj:8byv
• PDBsum: 8byv
• PubMed: 36768442
• UniProt: Q2FW12|RS3_STAA8 Small ribosomal subunit protein uS3 (Gene Name=rpsC)