Structure of PDB 8b3d Chain c Binding Site BS01

Receptor Information
>8b3d Chain c (length=264) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQL
TQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLP
PPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTF
AGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDR
AREQRRQLQKQERYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMNR
MDQKKHEKFSNQFN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8b3d Chain c Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b3d Structure of the Pol II-TCR-ELOF1 complex.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
C567 C577 C585 H588
Binding residue
(residue number reindexed from 1)
C161 C171 C179 H182
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000993 RNA polymerase II complex binding
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0009411 response to UV
GO:0016567 protein ubiquitination
Cellular Component
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8b3d, PDBe:8b3d, PDBj:8b3d
PDBsum8b3d
PubMed
UniProtQ2YD98|UVSSA_HUMAN UV-stimulated scaffold protein A (Gene Name=UVSSA)

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