Structure of PDB 7pgb Chain c Binding Site BS01

Receptor Information
>7pgb Chain c (length=113) Species: 187272,246200 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLE
SWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHHA
EDGERTDAYRDEV
Ligand information
Ligand ID4NB
InChIInChI=1S/C7H5NO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4H,(H,9,10)
InChIKeyOTLNPYWUJOZPPA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC(=O)c1ccc(cc1)[N+]([O-])=O
OpenEye OEToolkits 1.5.0c1cc(ccc1C(=O)O)[N+](=O)[O-]
ACDLabs 10.04O=[N+]([O-])c1ccc(C(=O)O)cc1
FormulaC7 H5 N O4
Name4-NITROBENZOIC ACID;
PARA NITROBENZOIC ACID
ChEMBLCHEMBL101263
DrugBank
ZINCZINC000001688307
PDB chain7pgb Chain X Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7pgb Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		T169 K170 G181
Binding residue
(residue number reindexed from 1)		T22 K23 G34
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005261 monoatomic cation channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7pgb, PDBe:7pgb, PDBj:7pgb
PDBsum7pgb
PubMed35655098
UniProtF7IVA8;
Q0ABW0

[Back to BioLiP]