Structure of PDB 6ys3 Chain c Binding Site BS01 |
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| >6ys3 Chain b (length=2888)
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gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacagugugac
ugcguaccuuuuguauaaugggucagcgacuuauauucuguagcaagguu
aaccgaauaggggagccgaagggaaaccgagucuuaacugggcguuaagu
ugcaggguauagacccgaaacccggugaucuagccaugggcagguugaag
guuggguaacacuaacuggaggaccgaaccgacuaauguugaaaaauuag
cggaugacuuguggcugggggugaaaggccaaucaaaccgggagauagcu
gguucuccccgaaagcuauuuagguagcgccucgugaauucaucuccggg
gguagagcacuguuucggcaagggggucaucccgacuuaccaacccgaug
caaacugcgaauaccggagaauguuaucacgggagacacacggcgggugc
uaacguccgucgugaagagggaaacaacccagaccgccagcuaagguccc
aaagucaugguuaagugggaaacgauguggaaggccagacagccaggaug
uuggcuuagaagcagccaucauuuaaagaaagcguaauagcucacugguc
gagucggccugcgcggaagauguaacggggcuaaaccaugcaccgaagcu
gcggcagcgacgcuuaugcguuguuggguaggggagcguucuguaagccu
gugaaggugugcugugaggcaugcuggagguaucagaagugcgaaugcug
acauaaguaacgauaaagcgggugaaaagcccgcucgccggaagaccaag
gguuccuguccaacguuaaucggggcagggugagucgaccccuaaggcga
ggccgaaaggcguagucgaugggaaacagguuaauauuccuguacuuggu
guuacugcgaaggggggacggagaaggcuauguuggccgggcgacgguug
ucccgguuuaagcguguaggcugguuuuccaggcaaauccggaaaaucaa
ggcugaggcgugaugacgaggcacuacggugcugaagcaacaaaugcccu
gcuuccaggaaaagccucuaagcaucagguaacaucaaaucguaccccaa
accgacacagguggucagguagagaauaccaaggcgcuugagagaacucg
ggugaaggaacuaggcaaaauggugccguaacuucgggagaaggcacgcu
gauauguaggugaggucccucgcggauggagcugaaaucagucgaagaua
ccagcuggcugcaacuguuuauuaaaaacacagcacugugcaaacacgaa
aguggacguauacggugugacgccugcccggugccggaagguuaauugau
gggguuagcggcgaagcucuugaucgaagccccgguaaacggcggccgua
acuauaacgguccuaagguagcgaaauuccuugucggguaaguuccgacc
ugcacgaauggcguaaugauggccaggcugucuccacccgagacucagug
aaauugaacucgcugugaagaugcaguguacccgcggcaagacggaaaga
ccccgugaaccuuuacuauagcuugacacugaacauugagccuugaugug
uaggauaggugggaggcuuugaaguguggacgccagucugcauggagccg
gccuugaaauaccacccuuuaauguuugauguucuaacguuggccccuga
ucgggguugcggacagugucugguggguaguuugacuggggcggucuccu
ccuaaagaguaacggaggagcacgaagguuggcuaauccuggucggacau
caggagguuagugcaauggcauaagccagcuugacugcgagcgugacggc
gcgagcaggugcgaaagcaggucauagugauccggugguucugaauggaa
gggccaucgcucaacggauaaaagguacuccggggauaacaggcugauac
cgcccaagaguucauaucgacggcgguguuuggcaccucgaugucggcuc
aucacauccuggggcugaaguaggucccaaggguauggcuguucgccauu
uaaagugguacgcgagcuggguuuagaacgucgugagacaguucgguccc
uaucugccgugggcgcuggagaacugaggggggcugcuccuaguacgaga
ggaccggaguggacgcaucacugguguucggguugucaugccaauggcac
ugcccgguagcuaaaugcggaagagauaagugcugaaagcaucuaagcac
gaaacuugccccgagaugaguucucccugacuccuugagaguccugaagg
aacguugaagacgacgacguugauaggccggguguguaagcgcagcgaug
cguugagcuaaccgguacuaaugaaccgugaggcuaac |
..<...<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[..(((.>>>.....<<<<<<<..<<<)))..].>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]].....
..........<<....>>....]].........<<<<.....>>>>....
..............>>>>>>>>>>>.......<<<<..<<<<.>>>>..>
>>>...<............>.<<<<<<....<<<<<<<<<<<<<..<<<.
..<<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>
>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<
<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>>
>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.
>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<<<<<.
....<<<...<<<.<<<<...<<.<...........>..>>...>>>>.>
>>..>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<<<<..
....>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((
.....<<<<<<...........<<..<<....<........<..<...<.
...<<.........>>....>..........<........>....>..>.
...>......>>.>>...........))).....>>>>>>.>>>...>>>
>>>><<<<<<<........>>>>>>>....>>>>>>..<<<<<...<<<.
.....<<<<<<<<....>>>>>>>>...>>>..>>>>>........>>>>
>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<
<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...<<<..
.<<<....>>>...>>>...>>>..<<<<<........>>>>>))<<<<<
<<.<..<<...<<<<....<<<<..<<<..<<<<<<<<<<<....(((..
.>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>>>>..
>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>>...>>>..
.>>>>.........>>>>...>>......>>.>>>>>>.>>>..>>....
.<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<
<<<<.<<...............<<<<<...............>>>>><<<
<<<.....<<<...<<<<.....>>>>...>>>...>>>>>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<...
.>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<........
<<<<<<.<<.>>..>>>>>>........>>>>>>>>..>>>>><<<<<<.
......>>>>>>........<...........<<<<<<.....>>>>>>.
....>....>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.
....>.....<<<<<........>>>>>..<<<<<<<<.(((.[[.....
.<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<..<<......
........<<........................................
.............>>.....>>..>>>>>>>>>>...<<<.<<<<<<...
..>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<
<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>
>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<<....>>
>>..>>>>.<<<....>>>.>>))).......<<<<<<<.((..>>>>..
))>>>>>>>.............>>>>..]]>>>>.......<<<<...<<
<<<<...<<.......>>...>>>>>>....>>>.>.......<<<<<.<
<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.
....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]
..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<..........
.....>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))).>>>>>>.
.>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>
....>>>.>>>>.......>>>>>>>..<<<<<.....>>>>>.....<<
..<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>
>>>...>>...>>>>>.>>>.....>>.....>>.>.. |
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| PDB | 6ys3 Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide |
| Resolution | 2.58 Å |
Binding residue
(original residue number in PDB) | K7 P8 T9 P11 R14 H15 K18 K28 E35 K36 S38 K39 S40 G42 R43 N44 N45 N46 G47 R48 I49 T50 T51 R52 H53 G56 H58 K59 Q60 A61 Y62 R63 I74 Y83 P85 N86 R87 K97 D98 G99 E100 R101 M146 K147 G149 K150 Q153 L154 A155 R156 S157 A158 G159 T160 Y171 L176 R177 S178 E180 R182 H200 M201 L205 G206 K207 A208 G209 R212 W213 R214 R217 P218 T219 V220 R221 G222 T223 A224 M225 N226 P227 V228 D229 H230 H232 G235 E236 R238 N239 F240 G241 K242 H243 P244 V245 T246 P247 W248 Q251 K253 G254 K255 K256 T257 R258 R262 T263 K265 R270 R271 |
Binding residue
(residue number reindexed from 1) | K6 P7 T8 P10 R13 H14 K17 K27 E34 K35 S37 K38 S39 G41 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 H52 G55 H57 K58 Q59 A60 Y61 R62 I73 Y82 P84 N85 R86 K96 D97 G98 E99 R100 M145 K146 G148 K149 Q152 L153 A154 R155 S156 A157 G158 T159 Y170 L175 R176 S177 E179 R181 H199 M200 L204 G205 K206 A207 G208 R211 W212 R213 R216 P217 T218 V219 R220 G221 T222 A223 M224 N225 P226 V227 D228 H229 H231 G234 E235 R237 N238 F239 G240 K241 H242 P243 V244 T245 P246 W247 Q250 K252 G253 K254 K255 T256 R257 R261 T262 K264 R269 R270 |
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