Structure of PDB 6spc Chain c Binding Site BS01

Receptor Information
>6spc Chain c (length=203) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VHPNGIRLGIVKEHTSVWYADRKNYADYLFADLKVREYLQDKLKSASVSR
IDIHRPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIE
EIRKPELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVS
GRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFK
GEV
Ligand information
>6spc Chain a (length=1519) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacaau
gcaagucagcggauaaagggagcuugcuccuggauucagcggcagacggg
ugaguaaugccuaggaaucugccugguagugggggauaacguccggaaac
gggcgcuaauaccgcauacguccugagggagaaagugggggaucuucgga
ccucacgcuaucagaugagccuaggucggauuagcuaguuggugggguaa
aggccuaccaaggcgacgauccguaacuggucugagaggaugaucaguca
cacuggaacugagacacgguccagacuccuacgggaggcagcagugggga
auauuggacaaugggcgaaagccugauccagccaugccgcgugugugaag
aaggucuucggauuguaaagcacuuuaaguugggaggaagggcaguaagu
uaauaccuugcuguuuugacguuaccaacagaauaagcaccggcuaacuu
cgugccagcagccgcgguaauacgaagggugcaagcguuaaucggaauua
cugggcguaaagcgcgcguaggugguucagcaaguuggaugugaaauccc
cgggcucaaccugggaacugcauccaaaacuacugagcuagaguacggua
gagggugguggaauuuccuguguagcggugaaaugcguagauauaggaag
gaacaccaguggcgaaggcgaccaccuggacugauacugacacugaggug
cgaaagcguggggagcaaacaggauuagauacccugguaguccacgccgu
aaacgaugucgacuagccguugggauccuugagaucuuaguggcgcagcu
aacgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacuca
aaugaauugacgggggcccgcacaagcgguggagcaugugguuuaauucg
aagcaacgcgaagaaccuuaccuggccuugacaugcugagaacuuuccag
agauggauuggugccuucgggaacucagacacaggugcugcauggcuguc
gucagcucgugucgugagauguuggguuaagucccguaacgagcgcaacc
cuuguccuuaguuaccagcaccucgggugggcacucuaaggagacugccg
gugacaaaccggaggaagguggggaugacgucaagucaucauggcccuua
cggccagggcuacacacgugcuacaauggucgguacaaaggguugccaag
ccgcgagguggagcuaaucccauaaaaccgaucguaguccggaucgcagu
cugcaacucgacugcgugaagucggaaucgcuaguaaucgugaaucagaa
ugucacggugaauacguucccgggccuuguacacaccgcccgucacacca
ugggaguggguugcuccagaaguagcuagucuaaccgcaagggggacggu
uaccacggagugauucaugacuggggugaagucguaacaagguagccgua
ggggaaccugcggcuggau
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<........<
<....<...<.<......<<<<....>>>>......>.>.>........<
<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<<....>
>>>>>......>>.>.....<<<....>>>....<<<<<<..<<....>>
>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<<....
...>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>
>.<<<<<.<.........>>>>>>.<<<<....>>>>....>>.......
.....<<<....<<<<....>>>>..>>>..>>.>>>>>>..........
....<<....>>..............<.<<<<<......<<<..<..<<.
.......>>..>..>>>.......>>>>>....>..<<<<<((......<
<<.....<<..))>>.......>>>..>>>>>..>>>>>>>>>.......
...<<<((.....<<<<...<<<.<<<<<<..<<<<<<<<<<......<<
<<<<.....>>>>>>....>>>>>>>>..>>.>>>>>>...<<<<<<<<.
..<<<<<<<....<<<<<...........................>>>>>
...........<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>
>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>...
.......<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>...<<.
.))>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>.
.)))).]<<<<<.<<<<<<<.<<.....<........<<...........
...................................<<<.........<..
....>........<......>....>>>.........<............
.....<<<<<<<<....>>>..<<<<......>>>>..>>>>>.......
......<...........<.........>..........>.......<<<
<<.....>>>>>..............................>.......
...............>>............................<....
..........>.......................................
...........................>......................
...............>>...>>>>>>>>>>.>>....<..<<.<.<<<<.
<<<..<<<<<<<<<<<<....<<<<<<.<<<...<<....>>.>>.>>>>
>>>...>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<
<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spc Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		V5 H6 I10 K27 A160 W167 R169 H176 T177 L178 I182 Y184 K199 W201
Binding residue
(residue number reindexed from 1)		V1 H2 I6 K23 A156 W163 R165 H172 T173 L174 I178 Y180 K195 W197
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6spc, PDBe:6spc, PDBj:6spc
PDBsum6spc
PubMed31611393
UniProtA0A140S919

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