Structure of PDB 5zwn Chain c Binding Site BS01

Receptor Information
>5zwn Chain c (length=101) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPKHELSRAELEELEEFEFKHGPMSLINDAMVTRTPVIISLRNNHKIIAR
VKAFDRHCNMVLENVKELWTEKKGKNVINRERFISKLFLRGDSVIVVLKT
P
Ligand information
>5zwn Chain P (length=480) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggaaaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuaguucauugaa
gucauugaugcaaacuccuuggucacacacacggcgcggaaggcguguuu
gcugacguuuccauucccuuguuucaaucauugguuaaucccuuuggguu
aaacugauuuuuggggcccuuuguuucuucugccuggagaaguuugacac
caaauucaaauugguguuaggggagcuggggccuuucaaaagagcuuugu
agaggcauucuuuuugacuacuuuucgcgugccauuuuaguuuuugacga
uucgaaugaacuaguuuaugaugaaguugagauuauuuggucgauuguag
uuugaagauguagucucaacuuugcucaaauuuuggaaggucuugguagg
aacggguggaucuuauaauuuuugauuuau
...........<<<<.<<<<<<<<.....>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<..>>>>>.>>>.
......>>>>>.>>>>>>>>.................>>>>>>>>>>>>>
><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<.<.<<<...>>>.>
.>>>>>>>..>>>>>>>((.......<<<<<....))>>>>>...<<<<<
<<<.......>>>>>>>>.>>>>><<<<<<<<<<<<<<<<<..<<...<<
.<<<<<..<<<<<..<<<<<<..<<.....<<<<...<<<<<<..<<<..
<<<<.<<<<<<<>>>>>>>..>>>>>>>.>>>>>>..>>>>.>>..>>>>
>>.>>>>>....>>>>>.>>...>>.....>>>>>>>>>>>>>>>>>.>>
>>>>..>>>.>>>>................
Receptor-Ligand Complex Structure
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PDB5zwn Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)		H11 L18 R49 N50 R63 H64 N66 R97 G98 D99
Binding residue
(residue number reindexed from 1)		H4 L11 R42 N43 R56 H57 N59 R90 G91 D92
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030532 small nuclear ribonucleoprotein complex
GO:0032991 protein-containing complex
GO:0034715 pICln-Sm protein complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwn, PDBe:5zwn, PDBj:5zwn
PDBsum5zwn
PubMed29794219
UniProtQ06217|SMD2_YEAST Small nuclear ribonucleoprotein Sm D2 (Gene Name=SMD2)

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