Structure of PDB 5xxu Chain c Binding Site BS01

Receptor Information
>5xxu Chain c (length=57) Species: 5811 (Toxoplasma gondii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPKLAKVEKVLGRTGSRGGVLQVRVTFMRSLIRNVKGPVREGDILALLET
EREARRL
Ligand information
>5xxu Chain 2 (length=1619) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguagucauaugcuugucuuaaagauuaagcc
augcaugucuaaguauaagcuuuuauacggcuaaacugcgaauggcucau
uaaaacaguuauaguuuauuugauggucuacauggauaaccgugguaauu
cuauggcuaauaccugcgcacaguguuuauuagauacagaaccaagguga
uucauaguaaccgaacggaucgcgcugcgacggaucauucaaguuucuga
ccuaucagcuuucgacgguacuguaauggacuaccguggcagugacgggu
aacggggaauuaggguucgauuccggagagggagccugagaaacggcuac
cacaucuaaggaaggcagcaggcgcgcaaauuacccaauccugauucagg
gagguagugacaagaaauaacaaccuggagugauuggaugauaggaaucc
aaaccccuuucagaguaacaauuggagggcaagucuggugccagcagccg
cgguaauuccagcuccaauagcguauauuaaaguuguugcaguuaaaaag
cucguaguuggauuucugcuggaaggccaauucuagcauccuucuggacu
uuuacuuugagaaaauuagaguguuucaagcaggcuugucgccuugaaua
cucagcauggaauaauaagauuucggcccuauuuugguuucuaggacuga
aguaaugauuaauagggacgguugggggcauucguauuuaacugucagag
gugaaauucuuagauuuguuaaagacgaacuacugcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuaggggcucgaagacgauca
gauaccgucguagucuuaaccauaaacuaugccgacuagagauaggaaaa
cgucaugacuucuccugcaccuuaugagaaaccaaagucuuuggguucug
gggggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggca
ccaccaggcguggagccugcggcuuaauuugacucaacacggggaaacuc
accagguccagacauaggaauugacagauugauagcucuuucuugauucu
augggugguggugcauggccguucuuaguugguggagugauuugucuggu
uaauuccguuaacgaacgagaccuuaaccugcuaaauaggaucaggaacu
ucguguucuuguaucacuucuuagagggacuuugcgugucuaacgcaagg
aaguuugaggcaauaacaggucugugaugcccuuagauguucugggcugc
acgcgcgcuacacugaugcauccaacgaguccuuggccgauaggucuagg
uaaucuugugaguaugcaucgugauggggauagauuauugcaauuauuaa
ucuucaacgaggaaugccuaguaggcgcaagucagcacguugcgccgauu
acgucccugcccuuuguacacaccgcccgucgcuccuaccgauugagugu
uccggugaauuauucggaccguuuuguggcccgaaaugggaaguuuugug
aaccuuaacacuuagaggaaggagaagucguaacaagguuuccguaggug
aaccugcggaaggaucauu
...<<<<<.{.[[[[>>>>><<<..<<<<<<...<<<<..<......<<<
.<<<..<<....<<....<<<.......>>>...>>.>>......<<..<
.....<<<..<<..<<....<<<<.........<.....<<<<<<.....
>>>>>>......>.........<<..<<<<<<.......(((((......
....>>>>>>....>>...<<<<...>>>>...>>>>...>>>>..>>>.
<<<....<<<....<<<<<<...........>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<.....>>>
..>>>..>...>>>>.....<<<.<....>...>>>.....<.<<<....
.......>>>.>.........<<<<<((....<.<<<<.....<<..))>
>.......>>>>>>>>>>..>>>>>>.>>>.........<<<[[.....<
.<<...<<<.<<.....<<<<<<<......>>>>>>>.....<...>...
.<<<<<.<<.......<<...<.......>..<<<.....>>>.....>>
.....>>.>>..>>>.....<<<<<<.<<<....)))))...>>>.>>>>
>>......>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<
......>>>......>.>>>>>.>.>>.......<<....>>...>>>>.
..>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<.<.<<<<<.<<
.<<<..>>>>>.>>>>>..>>>...<...]].>...>>.....>>>.>>>
.<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<
..<<.<<<<<<..<<<.<<<<<<......<<........>>.........
.<<<<<.<....<<<<<......<..<<........>>..>.......>>
>>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<.
.....>>>...>>.>>>....<<<<<.<<..<<<<..<<....<<<<<<.
....>>>>>>......>>..>>>>.>>....<<<<<<.....>>>>>.>.
.....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>
.>>>>.>>>.....<<<<<<<......<<.<<<.<<<<....>>>>.>>>
....>>.......>>>>>>>...........<<<<<<..........>>>
>>>..........>>>>>>....<<<<<<<.........>>>>>>>....
..>>...>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<<<<<
<..<<<..<<.<..<...<<<<<<<<.....>>>>>>>>...>..>.>>.
.>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB5xxu Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Resolution3.35 Å
Binding residue
(original residue number in PDB)		R15 S18 R19 P48
Binding residue
(residue number reindexed from 1)		R13 S16 R17 P38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xxu, PDBe:5xxu, PDBj:5xxu
PDBsum5xxu
PubMed28809395
UniProtA0A125YJ29

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