Structure of PDB 5gm6 Chain c Binding Site BS01

Receptor Information
>5gm6 Chain c (length=415) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNP
KLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLES
EDSKATRKIRERMLEESKRIAELQKRRELKQAGINVAIKKPKKKYGTDID
YNEDIVYEQAPMPGIYDTSTEDRQIKKKFEQFERKVNRKGLAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAESRMQHITQGRTSMKIQFKTAMPPTEVLLESIQSKVESIEQ
LQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEGQRKYYADYYAYRQEIRS
LEGRRKRLQAMLNSS
Ligand information
>5gm6 Chain E (length=103) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
uua
<<<<<<<<<<.....>>>>>>>>>>.........................
............<<<..<<<.....>>>...>>>................
...
Receptor-Ligand Complex Structure
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PDB5gm6 Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Resolution3.5 Å
Binding residue
(original residue number in PDB)		K35 S38 R169 Y207
Binding residue
(residue number reindexed from 1)		K27 S30 R107 Y145
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0071006 U2-type catalytic step 1 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gm6, PDBe:5gm6, PDBj:5gm6
PDBsum5gm6
PubMed27445306
UniProtQ03654|CEF1_YEAST Pre-mRNA-splicing factor CEF1 (Gene Name=CEF1)

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