Structure of PDB 8toc Chain b Binding Site BS01

Receptor Information

>8toc Chain b (length=534) Species: 154784 (Acinetobacter phage AP205)

MNMYKWVPESIRDSGEGQPSYSNNGDYAPSGPWVAAGIHTMPQSLRDSMR
NSIMVTAQARRDVIGPEWGPDGRFTGYASVIGTPDPKPADIVNKFTVERR
PVSNGNFQQRVKAGDIVVAPYTSDGKITVKLVAGQKDISSTPDYDYRIDS
SLASSAGFVVAGERWYYTKRHFIIPRYFQNWRMRRRKYVTGWVMPTFYSP
KEIFNRLKDSLVPDTGLVTQVWADNNTKRMDFLTAMAEIPQTLSSFLDAL
GYLGSLIKDFKRRRFFLNKAHQRIRNKLGVSFAERRSQIVSKYDRKIASA
RKPAIIVKLRQRKEKALKALDKMRVREEKKMIREFATQAASLWLSFRYEI
MPLYYQSQDVLDVIANSTSEFMTSRDFVAKAINIGIPLEWNLDQENLVSQ
PRHNVMVKSKLSPENNIGKTLSVNPFTTAWELLTLSFVVDWFVNFGDVIA
GFTGGYSDDSGATASWRFDDKKVFHLKNIPSAMVIVDINFYTRQVIDPRL
CGGLAFSPKLNLFRYLDAMSLSWNRSRLKISRAT

Ligand information

>8toc Chain R (length=4269)

ggagugaaccccggaggggguucgcugaaagccgaaucgaauucgacuuu
gcgugauucacaucacgucuuacucacgauacuaguaccgcgaguuaucu
ugugguaauuaaaaacuaccaggagauaacuuuaugaagaaaaggacaaa
agccuugcuucccuaugcgguuuucaucauacucagcuuucaacuaacau
uguugacugccuuguuuauguauuaccauuauaccuuuuaggagauggug
ucaugaacauguacaaauggguaccugaaaguauccgcgauucuggcgag
gggcaacccucuuauucaaauaauggugauuaugcaccgagcggcccuug
gguugcugcggguauucauaccaugccacaaucgcugcgggauuccauga
gaaauucuaucauggucaccgcgcaagcucgucgugaugucauuggcccc
gaauggggcccugacggacgcuuuacuggauaugcuucagugaucgggac
accugauccuaagccugcugauauugugaacaaguuuacaguugaacgca
gaccggucagcaacggaaauuuucaacagcgugugaaagcuggugacauu
guuguugcaccguauaccagugauggaaagauuacuguuaaacuagucgc
cggucagaaggacauuucaaguacuccugauuacgauuaucgaauugaca
guaguuuggcgucauccgccggauuuguuguugcuggugaacguugguau
uauaccaaacgucacuucauuaucccucguuacuuccaaaacuggcgcau
gcgccggcguaaguacguaacugguuggguaaugccaacguuuuauaguc
cgaaagagauuuuuaaucgccuuaaggauucguugguaccagauacuggg
uuagucacccaaguuugggcagacaacaacacaaaacggauggauuuccu
caccgcuauggcugaaaucccacagacucucucuucuuuucucgaugcgu
uggguuaccucggaucgcuuauuaaagauuuuaaacgucgucgcuucuuu
uuaaauaaagcgcaucaacguauccguaauaagcucggggugucuuucgc
agaaagaagaucacaaauuguaucuaaguacgaucguaagaucgcaucug
cccguaagccugcaauuauuguaaaauugcggcaacggaaagaaaaggcc
uuaaaagcccuagauaaaaugcguguucgagaggaaaagaaaaugauacg
ugaauuugccacucaggcagccucacuauggcuuucuuuucgguacgaga
ucaugccgcuuuauuaucaaucucaggacguauuggacguaauugccaac
ucgacuucugaauuuaugacaucgcgggacuuuguugcuaaagcaaucaa
cauuggaauuccuuuggaauggaaucuugaucaagaaaacuugguuucuc
aaccgagacacaaugugaugguuaaaucaaaauugucacccgaaaacaac
aucgggaagacucuuucaguuaauccauuuacaacagcuugggagcuguu
gacauuguccuucgucgucgacugguuugucaacuuuggugacgucaucg
caggguuuacuggcgguuacucagaugauucuggggcaacugcuaguugg
cgcuuugaugauaaaaagguauuccacuuaaagaauauccccucagcuau
ggugaucgucgacauuaacuucuacacccgucaggucauugacccgcggc
ugugcggggggcuugcuuucucccccaaacuuaaccuuuuccgguaucuu
gacgccaugaguuuaucauggaaucgaucucguuuaaagaucagucgagc
uacuugacaauuuucugcgcacccaucccggguggcgcccaaagugagga
aaaucacauggcaaauaagccaaugcaaccgaucacaucuacagcaaaua
aaauuguguggagugauccaacucguuuaucaacuacauuuucagcaagu
cuguuacgccaacguguuaaaguugguauagccgaacugaauaauguuuc
aggucaauauguaucuguuuauaagcguccugcaccuaaaccggaagguu
gugcagaugccugugucauuaugccgaaugaaaaccaauccauucgcaca
gugauuucagggucagccgaaaacuuggcuaccuuaaaagcagaauggga
aacucacaaacguaacguugacacacucuucgcgagcggcaacgccgguu
uggguuuccuugacccuacugcggcuaucguaucgucugauacuacugcu
uaaguggugauuacugugccuaaaagucaaaauaaacgacaaauaagacg
caguucuuccguuaauuacaagaauaucguuaaagcuugcaaugaugcaa
ugcuaaacgcuugugaucaacugaaguccacgaguauuccugcuuuccaa
ucaaacguccuuucggauguucuuucccucucugaugcggccgacauaac
agucaagcaccgaauuguuucuaaauucggcgagccugcugggucgagcc
uccgcgacguugcuuuuaacaauuauaaauuguucgaacaacaucuuggg
agcauuccucagauuacuaaucuguggcaggaaggaaaagaguuuuucuu
uuugcggaaagcaaaggcuaacuuggguaaaugguuaaaaacauuuaaac
uugacuauaauucuauuacagucgaguucaccccaggugagucuuauacc
ucggccacugggcacguaucgguguuugcuaagcuuuccaacuuagcuca
cuggacaugcacugcugacgucguugaugauguuugccaucuaguguauu
auaaucgcggccuaaaggcugccgcuagaaaacacaucggucugaugguc
ccaauugagggagagucuggguuugacaccuuuucucgccaccucauggg
uguuauauccaucguuccuggggcccgcggcgcauccgugccgaagaacc
aggaaacggaccguuuuaucgacguugaacccacuuucaauaugauucuc
cagcguuggguagcgggcgaaauuacucgcugcuuaacuuuagcuaagaa
ucaucuuggcgcaucacggaauauuaacgguaaaguuguauuucacgaug
cucaagaauugcacaaagaaaugauccgagaucuuucuuaugcuacuauu
gauuuuucaaacgcuucugauagcgucuugcugugggugguacagcuucu
uuuuccgaagcauguaucguauguuuugacacaguaucguucgucgacug
uccaacucgguucagaucuuaucgaaccgaauaaacuuucaaguauggga
aaugguuuuacuuuugaaguaaugacccuccucuuacugucgauagguag
aaucuuugauccuaccugccggguuuacggagaugauguuaucaucaaag
cagaaguagccgacgauuucaucaacacugugucauccauugccuucaug
acgaacaauaagaagaccuuuuugaagggucucuuucgugaaucaugcgg
ugcuuuccaauuugacacauuugacauccagucauuugaguucgaauggg
cugauaauuuuacugacguuauugcgaucugcaacaaacugaaguuaauu
aucgacgcugcucaaugcaacgaagcaguaauagcaauauuacgcaaugc
gcauaccgucaucugugaaugcaucccuguucuuugcaagggaccgcagc
cgccugauuucaaccucuuuuuaucucaauauguuuaugaugauaauugg
aagaagaaacagaugaaaucugauuuagccauaacuaagcuaaauagacu
cguugauaaacaaugggguuucuuuucagcuacacaucaucacccugagg
aauuauguuacguaaacauuccuguuuacgucccucgucgugauucuguu
caugcuggccagaaucuuuucguugaccuuucaaaucuuuacgcuuuacg
uuuuaccaaaucaacgguaagagguaaagguaaaugggucaauguucccc
acuggguuacaccgguugguucaauuuaucgugcuucccguaucagacag
caauacccuaacauaggggaauugccuaccugcuacuggucaccacauca
guuggacuugaucaccuccuaauaaaucuuuacgauuuauaauaauggua
uguacuaugaguauguauguagguugaaaacccuacccgcuuaggauugc
uuagcaguccuucccggca

..<<<<<<<<<<.(((>>>>>>>>>>.<<<<.<<<<<...>>>>>.>>>>
<<<<<<<....>>>>>>>....)))..<<<<<<...<<<<<.<<<<<<<<
<.<<<<<.........>>>>>.>>>>>>>>>....<<<<..<<<<.....
..>>>>.>>>>.....>>>>>.<<<<...<<<<<.<<..<<<<<......
.>>>>>..>>..<<<<<<<<...<<<<<<<...<<<...>>>.>>>>>>>
.>>>>>>>>.........>>>>>..>>>>>>>>>>.<<<<<<.<<<<<<<
<<....>>>>>.<<<....>>><<<<<<...<<<..<<<<<<<<<<<..>
>>>>>>>.>>>.>>>...>>>>>>>>>>.>>>>>>.<<<<....<<<<<<
.........>>>>>>...>>>>...............<<<<<..<<<<..
......>>>>.>>>>><<<<<.<<<<<<<.<<<<<<<.<<.<<<<<<<..
.>>>>>>>>>>>>.<<<<...<<.<<<<<<....>>>>>>.>.>...>>>
>..<<<<<<<<<<<<.......<<<.<<<<........>>>>.>>>...>
>>>>>>>.>>>>>>>>>>>>>>>......<<<<<<<<<<<<..<<<<<<.
.<<<<<<.<<.<<.......>>.>>.>>>>>>.>>>>>>.....>>>>>>
>>>>>>..>>>>>.<<<<<<<....<<<<<<<<<<<<<<.<<<<<<<<<.
..>>>>.>>>>>>>>..<<<<<<<<<<.<<<<<.......<<<<<<<<..
>>>>>>>..>......>>>>>.>>..>>>>>>>><<<<<<......<<<<
<..<<<.<<<<...>>>>..>>>..>>>>>>>>>>>..<<<<<<..<<<<
<.....>>>>>.>>>>>>.>>>.>>>>>>>>.....>>>.>>>>.....<
<<<<<...>>>.>>>................<<<<<<<<<.....<<<<.
..<...<<<<<<<...<<<<<<<<..<<<.....<<<<..<<<<<<..<<
...>>..>>>>>.>...>>>>>>>..>>>>>>>>>>>>>>>...>..>>>
>>>>>>>>>>..........<<<<<<..<.<<<<<....>>>>>.><<<.
.<<<<..<<<.<<<<<<.......>>>>>>>>>.>>>>..>>>...<<<.
......>>>.>>>>>>.....<<<<<<<<....<<<<<<<<<.<.<<<.<
<<<..<<<<<.....>>>>>..>>>>>>>.>.>>>>>>>>>....>>>>.
.>>>><<<<.....<<<.<<<.<<<<<<<<..<<<<..<....>.>>>>.
.>>..>>>>>>>>>.>>>.....>>>>....<<<<<<<....>>>>.>>>
...<<<<......<<<<...<<<.<<..<<<<<<<....>>>>>>><<<<
....>>>>.<<<<<.<<<<......>>>>..>>>>>..<<<<<.......
.>>>>>..>>.>>>.>>>>....>>>>....<<<<<<<<....>>>>>>>
>...<........>..<<<<<<.<<<<..<<<<.<.<<......<<<<<<
.<<.<<<.<<<<<<<<<<.<<<<<<....>>>>>>..>>>>>>>>>>.>>
>.>>.>>>>>>......<<<<<<<........>>>>>>>....>>>.>.>
>>.>>>>>>>>>>.........<<<<.<<<<..<<<<...>>>>.>>>>.
>>>>.<<<<.<..........>>>>>..........<<<<<<<<<<.<<<
<<<.<<<<<<.....>>>>>>....<<<<<.......>>>>>.>>>>>>.
>>>>.....<<<<<..<<<<<<<<.....>>>>.>>>>..>>>>>..>>>
>>>...<<<<<<......>>>.>>>.....<<<<<<.<<<<<<.<<<...
...>>>>>>>>>>>>>>>..........<<<<...<<<<<<<<<<....<
<.<.<<.<<<<<<........>>>>>>.>>.>.>>.>>>>>.>>>>>...
.<<<<<<......<<<<<<..<<<..<<<.<<<<<...<<<<....>>>>
>>>>>>>>.<<<<.<<<<<<.<<<.<<<<<..........>>>>>>>>.>
>>>>>..>>>><<.....<......>....>>.>>>..>>>>>>...<<<
<<<<<<....<<...<<<<<.....<<<.....>>>...>>>>>.>>...
>>>>>>>>>>>>>>><<<<<..<<<..<.<<<<<....>>>>>.>..>>>
..>>>>>>>>>.<<<<<<.<<....<<<.........>>>.....>>.>>
>>>>.<<<<.<<<.<<<<<<<<.....<<<<..<<<<<<<<....>>>>>
.>>>>.>>>>>>>>>>>.>>>.>>>>...............<<<<<<<..
.<<<<<<<<<....>>>>><<<.<<....<<.<<...<<<<<<<<....<
<<.<<.<<.<<<<<<.........>>>>>>...>>.>>>>>.>>>>.>>>
...>....<.<..<<<.<<<<<<<...>>>>>>>.>>>..>>....>>..
>>......<<<<<<<...>>>>>>.>..>>>>><<<<<<...>>>>>>..
>>>>.>>>>>>>.<<<<<<.<<<<<<<<<<<<<........>>>>>><<<
<<<<<<.<<<.....>>>.>>>>>>>>>...>>>>>>>.>>>>>>.....
.........<<<<<.<<.<<<<<<...<<<<<<........>>>>>>.>>
>>>>>>.>>>.>><<.<<<<<<......>>>>>>.>>..<<<<<<<....
......<<<<<<....>>>>>>>>>>>>>........<<<<<<<<<<<.<
<<<..<<<<<..<<<...<<<<.....>>>>...>>>....>>>>>>>>>
........>>>>>.<<<<<<<......<<<<<<....>>>>>>.....>>
>>>>>..>>>>>>..<<<<<.<<.....<<<<<<..<<<<<<.<<<<<<.
.<<<<<<<<<<<<<<<<........>>>>>>>>>>>>>....>>>.>>>>
>>.<<<<<<.<<<<<..<<<<<<<.<<<......>>>>>>>>>>..>>>>
>>>>>>>...<<<..<<<<<<.<<<<...>>>>>>>>>>.>>>...>>>>
>>.....<<<<<<<<......>>>>>.>>>..>>>>>><<<<<<<<<<<.
......>>>>>.>>>>>><<<<<<..<<<<<<<<<<<<<<.<<<<<<<..
......<<<<<<<.<<<...>>>>>>>>>>.............<<.<<<.
...<<<<.<<<<.....>>>>..>>>>..>>>..>>..>>>>>.<<<<<<
.<<<...>>>.>>>>>><<....<<<.<...<<<<<<...>>>>>>...>
.>>>....>>>>>>>>>.........>>>>>>>>>..<<<<<....<<<.
....<<...<<<<.<<<<<<<...>>>>>>>>>>>..>>.....>>>...
.<<<..<<<.<<<<<<.<<..<<<<.....>>>>..>>.>.>>>>>>>>.
.<<<<<<<<..<<<...<<<.<<<<<...>>>>>..>>>...>>>.>>>>
>>>>..<...<.....>...>..>>>.<<<<<<....>>>>>>.>>>>>.
>>>>>>..<<<<<<<<<..<<<.<<<<<..........>>>>>..>>>..
>>.<<..<............<<<<<<<<.<<....>>>>>.>>>>>....
>...>>...>>>>>>>..<<<.<<<<<<<.........>>>>>>>>>>..
.>>.>>>>>....<<<<<.<<<<..<<<<<...<<<..<<<<<..<<<<<
...((((((<<<<<<<<<....>>>>>>>>>.>>>>>..>>>>>..>>>.
...>>>>>..>>>>......<<<<<<<<<........<<<<<.<<<<<<.
<<<<<<<........>>>>>>>.>>>>>>>>>>>.>>>>>>>>>..>>>>
>............<<<<<<<<<<<<<.<<.<<<...<<.<<<.<<<...<
<<<<.<<<.)))))).>>>.>>>>>....>>>.>>>.>>....>>>>>.>
>>>>>>>>.>>>>........<<<<<<<.....>>>>>>>.......<<<
<<<<<<...>>>>>>>>><<<<<........>>>>><<<...<<<<..<<
...>>..>>>>...>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8toc Structural basis of Acinetobacter type IV pili targeting by an RNA virus
• Resolution: 3.11 Å
• Binding residue (original residue number in PDB): R99 V102 S103 N104 G105 N106 F107 Q108 V111 K112 G114 D115 I116 V117 Y121 S123 D124 G125 K258 D259 K261 R262 F265 F266 R273 K277 R285 Q288 K292 R295 K296 R301 K308 R312 K315 K322 Y348 F371 M406 K419 S422 S465 R467 N489 F490 Y491 R493
• Binding residue (residue number reindexed from 1): R99 V102 S103 N104 G105 N106 F107 Q108 V111 K112 G114 D115 I116 V117 Y121 S123 D124 G125 K258 D259 K261 R262 F265 F266 R273 K277 R285 Q288 K292 R295 K296 R301 K308 R312 K315 K322 Y348 F371 M406 K419 S422 S465 R467 N489 F490 Y491 R493

Gene Ontology

Biological Process

• GO:0039666 virion attachment to host cell pilus

Cellular Component

• GO:0044423 virion component

External links

• PDB: RCSB:8toc, PDBe:8toc, PDBj:8toc
• PDBsum: 8toc
• PubMed: 38553443
• UniProt: Q9AZ43