Structure of PDB 8ipx Chain b Binding Site BS01 |
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| >8ipx Chain 2 (length=3475)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau
guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcggguccggccgugucggcgg
cccggcggaucuuucccgcgcgggggaccgucccccgaccggcgaccggc
cgccgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccggg
acggcugggaaggcccggcggggaagguggcucgggggcccccgaguguu
acagcccccccggcagcagcacucgccgaaucccggggccgagggagcga
gacccgucgccgcgcucuccccccucccggcgcgccggggggggccgggc
caccccucccacggcgcgaccgcucggggcggacuguccccagugcgccc
cgggcgggucgcgccgucgggcccgggggaggccacgcgcgcgucccccg
aagagggggacggcggagcgagcgcacggggucggcggcgacgucggcua
cccacccgacccgucaaacacggaccaaggagucuaacacgugcgcgagu
cgggggcucgcacgaaagccgccguggcgcaaugaaggugaaggccggcg
cgcucgccggccgaggugggaucccgaggccucuccaguccgccgagggc
gcaccaccggcccgucucgcccgccgcgccggggagguggagcacgagcg
cacguguuaggacccgaaagauggugaacuaugccugggcagggcgaagc
cagaggaaacucugguggagguccguagcgguccugacgugcaaaucggu
cguccgaccuggguauaggggcgaaagacuaaucgaaccaucuaguagcu
gguucccuccgaaguuucccucaggauagcuggcgcucucgcagacccga
cgcccgccacgcaguuuuauccgguauggguaagaagcccggcucgcugg
cguggagccgggcguggaaugcgagugccuagugggccacuuuugguaag
cagaacuggcgcugcgggaugaaccgaacgccggguuaaggcgcccgaug
ccgacgcucaucagacccagaaaagguguugguugauauagacagcagga
cgguggccauggaagucggaauccgcuaaggaguguguaacaacucaccu
gccgaaucaacuagcccugaaaauggauggcgcuggagcgucgggcccau
acccggccgucgccggcagucgagaguggacgggagcggcggcccggagc
cccgcggacgcuacgccgcgacgaguaggagggccgcugcggugagccuu
gaagccuagggcgcgggcccggguggagccgccgcaggugcagaucuugg
ugguaguagcaaauauucaaacgagaacuuugaaggccgaaguggagaag
gguuccaugugaacagcaguugaacaugggucagucgguccugagagaug
ggcgagcgccguuccgaagggacgggcgauggccugcccuccgaucgaaa
gggagucggguucagauccccgaauccggaguggcggagaugggcgccgc
gaggcguccagugcgguaacgcgaccgaucccggagaagccggcgggagc
cccggggagaguucucuuuucuuugugaagggcagggcgcccuggaaugg
guucgccccgagagaggggcccgugccuuggaaagcgucgcgguuccggc
ggcguccggugagcucucgcuggcccuugaaaauccgggggagagggugu
aaaucucgcgccgggccguacccauauccgcagcaggucuccaaggugaa
cagccucuggcauguuggaacaauguagguaagggaagucggcaagccgg
auccguaacuucgggauaaggauuggcucuaagggcugggucggucgcgg
ccggcgccuagcagccgacuuagaacuggugcggaccaggggaauccgac
uguuuaauuaaaacaaagcaucgcgaaggcccgcggcggguguugacgcg
augugauuucugcccagugcucugaaugucaaagugaagaaauucaauga
agcgcggguaaacggcgguuaagaacgagauucccacugucccuaccuac
uauccagcgaaaccacagccaagggaacgggcuuggcggaaucagcgggg
aaagaagacccuguugagcuugacucuagucuggcacggugaaguuuuuu
cacugacccggugaggcgggggggcgagccccgaggggcucucgcuucug
gcgccaagcgcccggccgcgcgccggccgggcgcgacccgcuccggggac
agugccagguggggaguuuccugucgcagguguccuaaggcgagcucagg
gaggacagaaaccucccguggagcagaagggcaaaagcucgcuugaucuu
gauuuuuacgaauacagaccgugaaagcggggccgauccuucugaccuuu
uggguuuuaagcaggagguaaguuaccacagggauaggcuuguggcggcc
aagcguucauagcgacgucgcuuuuugauccuucgaugucggcucuuccu
aucauugugaagcagaauucaccaagcguuggauuguucacccacuaaua
gggaacgugagcuggguuuagaccgucgugagacagguuaguuuuacccu
acugaugauguguuguugccaugguaauccugcucaguacgagaggaacc
gcagguucagacauuugguguaugugcuuggcugaggagccaauggggcg
aagcuaccaucugugggauuaugacugaacgccucuaagucagaaucccg
cccaggcggaacgauacggcagcgccgcggagccucgguuggccucggau
agccggucccccgccgggguccggugcggagugcccuucguccugggaaa
cggggcgcggccggagaggcggccgcccccucgcccgucacgcaccgcac
guucguggggaaccuggcgcuaaaccauucguagacgaccugcuucuggg
ucgggguuucguacguagcagagcagcucccucgcugcgaucuauugaaa
gucagcccucgacacaaggguuugu |
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<<...<<<<<<<<........<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>...>>>>>>>>..>>>>>>>>>>.......<<<<<<<........>>>
>>>>.....(((((..<<<<<<)))))..]]]..................
................<<....>>...............<<<......>>
>..................................<<<<<<<<..<<<.<
<...<<<<<<<<.<<<.....<<<<<<<<<<<..<<<<<<<.......<<
....<<<<.<<<..<<.<..>.>>>>>>>>>>>......>>>>...>>>>
>>>>>>>>>>......>>>.>>>.>>>>>...<<<<<<<<<<<<<<<<<<
.<<<<...<<..<<<..<.<<<<......<<<<<<<<..>>>>>>>>...
....>>>>.>.>>>........>>>>>>...>>>>>>>>>>.........
...........<<<<<<.<<<<<<<............>>>>>>>.<<<<<
<.<.<<.<<<<<<<<<<.<<<<<<.<<<<<................>>>>
>.>>>>>.>.>>>>>>>.>>>...>>.>..>>>>.>>..<<<<<<<<<..
.....>>>>>>>.>>....>>>>>>.....>>>.>>>>>...>>>>>...
>>>>>>>>..<<<<.....>>>><<<<<<....<<<<<<<<<<<<<..<<
<...<<<<........>>>>.....>>>...<<....>>...<<<<<<<.
.....>>>>>>>..<<<<<...<<<..<<<..[[....(((>>>..>>>.
...>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>>>.>>....>>>
>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<
<<<<<....>>>>>>>.....>>>...<<<..<<.<<........>>>>.
>>>....>>>>>>>>>...<<.......>>......>>>>>>...>..>.
>>..<<<<<<....<.<........>.><<<<<<<<<<............
..........<<<.<<<<<<.........>>>>...<<<<<<<<<.....
....>>>>>>>>>....>>>>>>>>>>>>.>>>..<<<<.<<<<<.....
>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<(((.....
..<<<<<.....<<.........<<<.<<<<<<<<<<.......<<<<<.
<<....<<.........>>....>>.........<<......>>...>>>
>>...>>>>>>>>>>>>>..........))).>>...>>>>>..>>>...
>>>>>>><<<<<<.<<<..........)))....]]..............
..............>>>>>>>>>....>>>>>>.<<<<<<<<<<.<<...
...<<<<.<<<<....>>>>>>>>...>>>>>>>>>>.>>.....>>>>>
><<<....<<.....<<<<<<.......>>>>>>.<<<.....<<<<<.<
<...<<<<<....<<.....>>..>>>>>....((<<<<<<...<<....
<<<....>>>.............<<<<........>>>>.....>>....
>>>..<<<<<........>>>>>))<<<<....<<<<<...<<<<<<<..
..>>>>>>>...<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<
<<<<<<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<.....<<
<.....>>>.....>>>>>>>>..>>>>>.....<<<<<<<.......>>
>>>>>>>>>.>.>>>>>>>>>>>>.........>>>>>>>..>.......
...>>.>>>.>>>>.>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>....<<<<.....<<<<<<<.<<...............<
<<<<....<<..>>.....>>>>><<.<<<<<<<<<<<..<.........
...>.......>>>>>..>>>>>>.>>............<<<<<<<<<..
<<<.........>>>..<<<<<<<....<<<<.....>>>>......>>>
>>>>.......<<<..<<<<<<....<<<.....<<<<....>>>>....
.>>>.>>>>..>>>>>.........>>.>>>>>>>.....>>.>>>>>>>
..>>>>>>...>>>....<<<<<........>>>>>....(((((..{{{
........(((((.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<...>>>
>>>...<<<<<.....<<<<.....<..............>.........
.......<<<<<<<<<<<.....>>>>>>>>>>>..>>>>..>>>>>...
.>>>>>>>>>..>>>>>...<<......>>.........<<<<<<...<<
<<<<.......>>>>>>...........((......>>>>>>....<<<.
.<<<<....>>>>..>>>.<<<....>>>...))....(((((...(((.
.>>>>>>.))).)))))...]]]]..}})))))..........<<<<<<.
................>>>>>>.................<<<<.<<<<<<
..<.<.<<<<<......>>>>>...>.>.<<<.........>>>.....>
>>>>..>...>>>>......<<<<<<<....>>>.>>>>........}}}
.))))).....<<<<<<.<..<<<..<.<<<<<.................
>>>>>.><<<<....<<<<....<<.<<<<<<.}}}..>>>>..>>.>>.
..>>>>...>>>><<<<<...<<<<<...........>>>>>...>>>>>
.>>>...>.>>>>>>.....<<<<<<<.<<..<<<<....<<<.......
.<<<<<.<<<<....>>>>.>>>>>.......>>>...<<<..<<<<...
.<<<<.<<<<<<<......>>>>>>>>>>>...>>>>..>>>........
......>>>>..>>>>>>>>><<<<<.<.............>....<<.<
<<<<<<.<<.....<<<<.<..<<<<<......>>>>>..>>>>>....>
>....>>>>.>>>.>>..>>>>>.. |
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| PDB | 8ipx Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. |
| Resolution | 4.3 Å |
Binding residue
(original residue number in PDB) | K2 A3 S4 G5 Y63 Q66 F68 K70 P72 L73 R87 S88 R95 R111 G114 A115 R116 H117 R118 R120 R139 H146 D147 S148 P155 H156 V158 R160 R161 H163 P165 R166 T168 T169 K170 P172 N173 T174 F175 F176 |
Binding residue
(residue number reindexed from 1) | K2 A3 S4 G5 Y63 Q66 F68 K70 P72 L73 R87 S88 R95 R111 G114 A115 R116 H117 R118 R120 R139 H146 D147 S148 P155 H156 V158 R160 R161 H163 P165 R166 T168 T169 K170 P172 N173 T174 F175 F176 |
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| Enzyme Commision number |
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