Structure of PDB 8c00 Chain b Binding Site BS01

Receptor Information
>8c00 Chain b (length=129) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGY
VILTTSAGIMDHEEARRKHVSGKILGFVY
Ligand information
>8c00 Chain 2 (length=1425) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguuacaugguauaacugugguaauucua
gagcuaauacaugcuuaaaaucucgaagagauguauuuauuagauaaaaa
auugaugauucauaauaacuuuucgaaucgcauggccgcuggcgaugguu
cauucaaauuucugcccuaucaacuuucgaugguaggauaguggccuacc
augguuucaacggguaacggggaauaaggguucgauuccggagagggagc
cugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuacc
caauccuaauucagggagguagugacaauaaauaacgauacagguuguau
uggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggcaag
ucuggugagcagccgcggauuccagcuccaauagcguauauuaaaguugu
ugcaguuaaaaagcucguaguugaacuuugggcccgguuggccaacgggg
ccuuuuuuacuuugaaaaaauuagaguguucaaagcaggcgugcucgaau
auauuagcauggaauaauagaauaggacguuugguucuauuuuuuucuag
gaccaucguaaugauuaauagggacggucgggggcaucaguauucaauug
ucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcau
uugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucgaaga
ugaucagauaccgucguagucuuaaccauaaacuaugccgacuagggauc
gggugguguuuuuaaugacccacucggcaccuuacgagaaaucaaagucu
uuggguucuggggggaguauggucgcaaggcugaaacuuaaaggaauuga
agggcaccaccaggaguggagccugcggcuuaauuugaaacucaccaggu
ccacacaauaagauugacagauugagagcuuucuugauuugugguagugg
ugcuagcaugcuggucacuguucugggcgcacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauagagcauuguaauuauugcucuucaacgaggaauu
ccuaguaagcgcaagucaucagcuugcguugauuacgucccugcccugua
ccuaguaccgauugaauggcuuagugaggccucaggaucugcuuagaguc
agagcggagaauuuggacaaacuuggucauuuagaggaacuagguuuccg
uaggugaaccugcggaaggaucauu
..<<<<<.[[((((>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<.......>>...>>.>>......<<......
..<<<..<<..<<....<<<........<<......<<.<<<.....>>>
.>>......>>........<<<<<...>>>>><.<.<<<<<<......((
(...........>>>>>>.>...>...<<<<..<<<.>>>.>>>>....>
>>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>
>>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<
..........>>>.>>.<.<<....>>.>...>>>>>>.........<<<
....<<<.....>>>..>>>..>....>.>.....<<<<<<<<.>>>>>>
>>......<<..<...........>..>>.........<<<<<((....<
.<<<<...<<..))>>.....>>>>>>>>>>..>>>>>>>>>>.......
..<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<..>>>>.>>>
>>>...<<<<<.<<.......<<...<.......>..<<<..>>>....>
>......>>.>>..>>>.........<<<..<<<<<<<<....))).>>>
>>>>>.>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<
...<<<..(...>>>......>.>>>>>>..>>.......<<....>>..
.>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<
<<..)......>>>>...>>>>>>>>..........<<<.<<.<<<..<<
<<<<<<.<<<......>>>>>>>>>>>..>>>...<<..]]>>...>>..
...>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]]..
<<<<<<..<<..<<<<<..<<<.<<<<<<...............<<<<<.
<..<<<<<.......<<.<<........>>.>>.....>>>>>..<<<<.
.<<<<<<..>>>>>>>>>>>.>>>>>..>>.>>>>.>>>.....<<<<<<
<......<<.....<<..<<<<....>>>>..>>....>>.......>>>
>>>>......<....<<<<<<..........>>>>>>....>.....>>>
>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>...
..<<<..<<....<<<<<<<<.<<<..<.<<..<...<<<<<<.......
..>>>>>>...>..>>.>..>>>.>>>>>>>>...>>..>>>...<<<<<
<<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c00 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T2 S4 N16 K19 K22 R28 K32 R57 K71 V74 S76 R78 N80 K82 I83 T106 S107 R118 H120 Y130
Binding residue
(residue number reindexed from 1)		T1 S3 N15 K18 K21 R27 K31 R56 K70 V73 S75 R77 N79 K81 I82 T105 S106 R117 H119 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c00, PDBe:8c00, PDBj:8c00
PDBsum8c00
PubMed36996028
UniProtP0C0W1|RS22A_YEAST Small ribosomal subunit protein uS8A (Gene Name=RPS22A)

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