Structure of PDB 7syp Chain b Binding Site BS01

Receptor Information
>7syp Chain b (length=101) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVR
DISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRF
R
Ligand information
>7syp Chain 2 (length=1680) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau
gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc
ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua
gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa
caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa
uccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcuc
guaguuggaucuugcucggcgccggcccgaagcguuuacuuugaaaaaau
uagaguguucaaagcaggccgccuggauaccgcagcuaggaauaauggaa
uaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauuaa
gagggacggccgggggcauucguauugcgccgcuagaggugaaauucuug
gaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuuca
uuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucgua
guuccgaccauaaacgaugccgaccggcgaugcggcggcguuauucccau
gacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggggga
guaugguugcaaagcugaaacuuaaaggaauuuggcgaagggcaccacca
ggaguggagccugcggcuuaauuugacucaacacgggaaaccucacccgg
cccggacacggacaggauugacagauugauagcucuuucucgauuccgug
ggugguggugcauggccguucuuaguugguggagcgauuugucugguuaa
uuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgaccccgg
ucggcguaacuucuuagagggacaaguggcguucagccacccgagauuga
gcaauaacaggucugugaugcccuuagauguccggggcugcacgcgcgcu
acacugacuggcucagcgugugccuacccuacgccggcaggcgcggguaa
cccguugaaccccauucgugauggggaucggggauugcaauuauucccca
ugaacgaggaauucccaguaagugcgggucauaagcuugcguugauuaag
ucccugcccuuuguacacaccgcccgucgcuacuaccgauuggaugguuu
agugaggcccucggaucggccccgccggggugcccuggcggagcgcugag
aagacggucgaacuugacuaucuagaggaaguaaaagucguaacaagguu
uccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<.........<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<......<<....<<<<.........<<.....<<.<<.....
..>>.>>......>>.........<<<<...<<<<<<....>>>>>>...
>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<
...>>>>>>>..>.>>>...>>....>>>.<<<....<<<....<<<<<<
<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<<..>>>.>...>>>
>>>.........<<<...<<<<.....>>>.>>>>......>>.>.....
<<<..<<<..<<<....>>>...>>>...>>>......<<..<.......
....>..>>.........<<<<<((......<<<<.....<<..))>>..
.....>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<
...<.<.<<....<<<<<<.<<..>>>>>>.>>..<<<<<<.<.......
<<...<.......>.<<<<.>>>>...>>......>.>>>..>>>.....
...<.<<.<<<<<<<...............>>>>>>>.>>.>....>>..
..<<<<<<..<...<<<<..<<<.<<<<<<<<...<<<......>>>...
...>>>>>>>>.>>>.......<<....>>...>>>>..>..>>>.>>>.
..>.>...>>.>....<<<<<<....<...<<<<.<.....>.>>>>...
>.>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<........
>>>>>>>>>.>..>>>...<<..))>>...>>.....>>>.>.>.<<<..
....<<<......>>>....>>>..)))).]..<...<<<<<<<..<<..
<<<<<.<<<<.<<<<<<......<<........>>..........<<<<<
......<<<<<<........<..<<........>>.>.......>>>>>>
.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<....
..>>>...>>.>>>....<<<...<...<<<<..<<<<<<<<<<<<..>>
>>.>>>>>>>>..>>>>..>.....<<<<<.....>>>>>........>>
>....>>>.>>>.....>>>>>>>>......>>>>>...>>.>>>>.>>>
.>...<<.<<<........<.......<<<.<<<<....>>>>.>>>...
.>.........>>>.>>......<.....<<<<<..........>>>>>.
....>.....>>>>>.....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>..>.......<..<<.<..<<<<.<<....<<<<<<<<.
<<<..<<<<.<<...<<<<<..<<..............>>....>>>>>.
..>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<
<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7syp Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		T2 K3 K4 R5 R6 N7 N8 R10 K12 K13 G14 R15 H17 K32 K34 I36 K37 K38 F39 Y68 K70 V75 I79 K82 V84 R85 R87 S88 R89 R92 K93 R95 P97 P98 R100
Binding residue
(residue number reindexed from 1)		T1 K2 K3 R4 R5 N6 N7 R9 K11 K12 G13 R14 H16 K31 K33 I35 K36 K37 F38 Y67 K69 V74 I78 K81 V83 R84 R86 S87 R88 R91 K92 R94 P96 P97 R99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7syp, PDBe:7syp, PDBj:7syp
PDBsum7syp
PubMed35822879
UniProtG1TFE8|RS26_RABIT Small ribosomal subunit protein eS26 (Gene Name=RPS26)

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