Structure of PDB 7oht Chain b Binding Site BS01 |
| >7oht Chain b (length=453) Species: 559292 (Saccharomyces cerevisiae S288C)
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MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKV
KYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISR
AKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYL
EQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFT
TKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCV
LYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDE
ERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKQPQ
ARDDVKRTPFIPESVKNLKKYDPEDPNRRKLARDIEAENGGAGVFNVNLK
DKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENEG
FYN |
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| >7oht Chain 1 (length=1485)
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cuauuggaacaggacgucauagagggugagaaucccgugugggaccgaua
guaagaacugagagugaaaaaguacgugaaauuguugacaggccagcauc
aguuuugguggcaggauaaauccauaggaauguagcuugccugguaagua
uuauagccugugggaauacugccagcugggacugaggacugcgacguaag
ucaaggaugcuggcauugcgaguguuuggguguaaacccauacgcgaacg
uaggguccugggauaagagcauaguuccugccgaaguuucccucaggaua
gcagaagcucguaucaguuuuaugagguaaagcgaacuuuaaauauguaa
gaaguccuuguuugaacguggacauuugaaugaagagcuuuuagugggcc
auuuuugguaagcagaacuggcgaugcgggaugaaccgaacguagaguua
aggugccggaauacacgcucaucagacacacaaaagguguuaguucaucu
agacagccggacgguggccauggaagucggaauccgcuaaggagugugua
acaacucaccggccgaaugaacuagcccugaaaaggauggcgcucaagcg
uguuaccuauacucuaccgucaggguuaugcccugacgaguaggcaggcg
uggaggucagugagaagccugacaaggucgggucgaacggccucuaguga
aucagcgggggaagacccuguugagcuugacucuagguggggaguuuggg
ggcggcacaucuguuaaacgauaagcagauguccuaaggggggcucaugg
agaacagaaaucuccaguagaacaaaaggaaaagcccccuugauuuugau
uuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuauag
aggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagcg
uuagcgacauugcuuuugauucuucgaugucggcucuuccuaucauaccg
aagcagaauucgguaagcguuggauuguucacccacuaauagggagucug
gguuuagaccgucgugagacagguuaguuccuacugaugaauguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcaugccgcgaagcuaccauccgcuggauu
auggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguagaguagccguuacg
aucugcugagauuaagccuuuguugucugauuugu |
<..............((......<<<.....))>>>....>.........
.......<...>.............................<<<<<<<.<
<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<<...>>>>>>.
......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>
>>.....>>>>>>>..<<<........<<<<....>>>>...........
.....<<<..>>>.....>>>.....<<<<<<....<.<<<....>>>.>
<<.<<.<......<<<.<<<<<<.......................>>>>
...<<<<..<<<..>>>..>>>>.....>>>>>.....>.>>.>>..<<<
<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<..
<<<<(((.....<<<<<<.....<<.........<<<.<<<<<<<<<<..
.....<<<<<.<<....<<.........>>....>>.........<<...
...>>...>>>>>...>>>>>>>>>>>>>.........))).>>...>>>
>>>.>>>>..>>>>>>><<<<<<<<<...>>>>>>>>>....>>>>>>..
.<<<<<<..<<.....<<<<<<.....>>>>>>...>>.>>>>>>.....
<<<<<..<<......<<<<<.<<.<<<..<<<<<......>>>>>.....
.<.<..<<.<<<<<..........>>>>>.>>.....<<<<<<<...<<<
.<.........>.>>>.................>>>>>>>...<<<..<<
<<.......>>>>..>>>.<<<....>>>...>.>........<.....>
............>>>...>>>>>>>..............<<<<<...<<.
...>>...>>>>>.................<<<...<<<<<..<.<<<<<
<<......>>>>>>>...>.<<<.........>>>.....>>>>>..>>>
......<<<<<<<....>>>.>>>>.....>>.>>>>>....<<<<<<<<
..<<<<.<.<<<<<<...............>>>>>>.><<<<<...<<<<
...<<<<<<<<<<<....>>>>>.>>>>>>..>>>>..>>>>>.<<<<..
.<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>....
..<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<<.<..<<<<<.>>>>>.
.>>>>>...>>>....>>>>.>>>>>..>>>>>.. |
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| PDB | 7oht Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. |
| Resolution | 4.7 Å |
Binding residue
(original residue number in PDB) | K6 P9 D19 I20 L22 N23 Q26 R27 K28 T31 V32 I33 R34 P35 G36 K38 R43 M47 K49 N70 I71 N72 K92 I93 L95 A96 S99 R100 S103 R110 R114 K117 F118 F123 K126 K129 R135 T138 K142 R154 Q155 R159 S162 K189 S190 Y197 F199 V206 H208 N233 G410 |
Binding residue
(residue number reindexed from 1) | K6 P9 D19 I20 L22 N23 Q26 R27 K28 T31 V32 I33 R34 P35 G36 K38 R43 M47 K49 N70 I71 N72 K92 I93 L95 A96 S99 R100 S103 R110 R114 K117 F118 F123 K126 K129 R135 T138 K142 R154 Q155 R159 S162 K189 S190 Y197 F199 V206 H208 N233 G393 |
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