Structure of PDB 7ohp Chain b Binding Site BS01

Receptor Information
>7ohp Chain b (length=394) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQLSWKDIPTVAPANDLLDIVLNRTQTRIRAFYMRKVKYTGEGFVEKFED
ILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISRAKSLVEQVARDYV
RLFQCKQLKRAALGRMATIVKKLRDPLAYLEQVRQHIGRLPSIDPNTRTL
LICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAID
TPGILMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKP
LFANKSVMVVINERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEK
LLASRTPFIPESVKNLKKYDPLARDIEAENGGAGVFNVNLKDKYLLEDDE
WKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENEGFYN
Ligand information
>7ohp Chain 1 (length=1567) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacucaauaagcggagg
aaaagaaaccaaccgggauugccuuaguaacgcgagugaagcggcaaaag
cucaaauuugaaaucugguaccucggugcccgaguuguaauuuggagagg
gcaacuuuggggccguuccuugucuauguuccuuggaacaggacgucaua
gagggugagaaucccguguggcgaggagugcgguucuuuguaaagugccu
ucgaagagucgaguuguuuaugcagcucuaagugggugguuccaucuaaa
gcuaaauauuggcgagagaccgauagcgaacaguacagugauggaaagau
gaaaagaacuuugagagagugaaaaaguacgugaaauuguugaaaggaag
ggcauuugaucagacaugguguuuuguucucgcauuucacugggccagca
ucaguuuugguggcaggauaaauccauaggaauguagcuugccgguaagu
auuauagccugugggaauacugccagcugggacugaggacugcgacguaa
gucaaggaugcuggcaaaugguuauaugccgccgucuugaaacacggacc
aaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgua
augaacgagguuggggccucgaagaggugcacaaucgaccgauccugagg
auggauuugguaagagcauagcuguugggacccgaaagauggugaaacca
ucuaguacugguuccugccgaaguuucccucaggauagcagaagcucguu
caguuuuauguaagaaugaagcuuuuagugggccauuuuugggcagaacu
ggcgaugcgggaugccgaacguagaguuaaggugccggaauacacgcuca
agacaaaagguguuaguucaucuagacagccggacggugccauggaaguc
ggaaccgcaggaguguguaacaacucaccggccgaaugaacuagcccugg
gcgcucaagcguguuaccuauacucuaccgucaggguugauaugcccuga
cgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucgg
gucgaacggccucuagugcagaucuuggugguaguagcagcgaaaccaca
gccaaggcgggaaucagcauaccgaagcagaauucgguaagaugaauguu
accgcaauaguaauugaacuuaguacgagaggaacaguucauucggauaa
uugguuugcggcugucugaucaggcagccgcgaagcuacauccgcuggau
uauggcugaacccucuaagucagauccaugcuagaacgcggugauuucuu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguacugcugagauuacc
uuuguugucugauuugu
..........................<<<<<<..........>>>>>.>.
........<<....>>...<<<<......<<....>>.....>>>>...<
<<...........<<.<<<<<<..>>>>>>.>>.............<<<<
<<<.<<<<<<<<<<<<<<<<<<<<<....<<<<......>>>>.((....
..<<<.....))>>>..>.>>>>>>>>..>>>>>>>>....>>>>>>>>>
>>........<<<<<<<....>>>>>>>.....<<<<<<..>>>>>>..>
>>.................................<<....>>.......
........<<<...>>>.................................
<<<<.<<<<<<..............<......>..........<<<<<<<
.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<........>>>
.......>>>>>>>>..>.>>>>>.>>>>>>>>>>........<<<....
>>>.....>>>>>>>....>>>>>.>>>>>.<<<<........>>>><<<
<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...
........<<<<<..<<<<<...>>>>>...>>>>>.<<<..<<<.....
..>>>...>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<...>>>>
>>>....>.>>..<<<<<<......<.......>...<<<<<<<<<...<
<<.<<.........>>>>>>>>>>>>.>>..<<<<....<<..>>....>
>>>....<<<....>>>...<<<<<<<..<<<<(((.....<<<<<<...
<<.....<<<.<<<<<<<<<........<<<<<.<<<..<<.........
>>..>>>.......<<......>>...>>>>>....>>>>>>>>>>>>.)
)).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......>>>>>>>
>>....>>>>>><..<<<<<<<.<<......<<<<.<<<<....>>>>>>
>>...>>>>>>>>>...>.....>>>>>><<..............>>...
............<<<.....<<<<<<......>>>>>>..>>>....<.<
<<<<<..<<<<.<.<<<<<<...............>>>>>>.><<<<<..
.<<....<<<<<<<<........>>>>>>>>.....>>.>>>>>.<<<<.
..<<<<<..........>>>>>..>>>>.>>>>....>>>>>>.>.....
.<<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>.><<<<<........
.............<<<<<.<<<.<<<....<<......>>...>>>..>>
>..>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohp Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S4 K6 F123 R154 Q155 R159 P161 S162 Y197 A198 F199 V206 G207 H208 R400 V411
Binding residue
(residue number reindexed from 1)		S4 K6 F103 R134 Q135 R139 P141 S142 Y177 A178 F179 V186 G187 H188 R324 V335
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohp, PDBe:7ohp, PDBj:7ohp
PDBsum7ohp
PubMed34813592
UniProtQ02892|NOG1_YEAST Nucleolar GTP-binding protein 1 (Gene Name=NOG1)

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