Structure of PDB 7o2l Chain b Binding Site BS01

Receptor Information
>7o2l Chain b (length=196) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAA
DTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVA
GYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEE
TVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
Ligand information
Ligand IDV08
InChIInChI=1S/C7H12O4/c1-4(2)5(3-8)6(9)7(10)11/h3-6,9H,1-2H3,(H,10,11)/t5-,6+/m0/s1
InChIKeyYIJPJSMEWHRJCU-NTSWFWBYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CC(C)C(C=O)C(C(=O)O)O
OpenEye OEToolkits 2.0.7CC(C)[C@H](C=O)[C@H](C(=O)O)O
CACTVS 3.385CC(C)[CH](C=O)[CH](O)C(O)=O
CACTVS 3.385CC(C)[C@H](C=O)[C@@H](O)C(O)=O
FormulaC7 H12 O4
Name(2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid
ChEMBL
DrugBank
ZINC
PDB chain7o2l Chain b Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7o2l Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		T1 G47
Binding residue
(residue number reindexed from 1)		T1 G47
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004298 threonine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex
GO:0034515 proteasome storage granule

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7o2l, PDBe:7o2l, PDBj:7o2l
PDBsum7o2l
PubMed35469007
UniProtP38624|PSB1_YEAST Proteasome subunit beta type-1 (Gene Name=PRE3)

[Back to BioLiP]