Structure of PDB 7m4x Chain b Binding Site BS01

Receptor Information
>7m4x Chain b (length=225) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YNVSMRDLLQAGAHFGHQTRFWNPKMRQYIFGARNKIHIINLEHTVPALN
DALNFANQLASKKNKVLFVGTKRAASNIIREQAQRAGQPYVDHRWLGGML
TNWKTLRQSINRLKDLQTQSQDGTFAKLTKREALERTREMEKLERSLGGV
KNMGGLPDALFVIDVDHEAIAIKEAKNLGIPVIGIVDTNSNPDNVDYVIP
GNDDAIRAVTLYASAMADAILAGKE
Ligand information
>7m4x Chain a (length=1528) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaacugaagaguuugaucauggcucagauugaacgcuggcggcaggcuua
acacaugcaagucgagcgggggaagguagcuugcuaccggaccuagcggc
ggacgggugaguaaugcuuaggaaucugccuauuagugggggacaacauc
ucgaaagggaugcuaauaccgcauacguccuacgggagaaagcaggggau
cuucggaccuugcgcuaauagaugagccuaagucggauuagcuaguuggu
gggguaaaggccuaccaaggcgacgaucuguagcgggucugagaggauga
uccgccacacugggacugagacacggcccagacuccuacgggaggcagca
guggggaauauuggacaauggggggaacccugauccagccaugccgcgug
ugugaagaaggccuuaugguuguaaagcacuuuaagcgaggaggaggcua
cucuaguuaauaccuagggauaguggacguuacucgcagaauaagcaccg
gcuaacucugugccagcagccgcgguaauacagagggugcgagcguuaau
cggauuuacugggcguaaagcgugcguaggcggcuuauuaagucggaugu
gaaauccccgagcuuaacuugggaauugcauucgauacuggugagcuaga
guaugggagaggaugguagaauuccagguguagcggugaaaugcguagag
aucuggaggaauaccgauggcgaaggcagccaucuggccuaauacugacg
cugagguacgaaagcauggggagcaaacaggauuagauacccugguaguc
caugccguaaacgaugucuacuagccguuggggccuuugaggcuuuagug
gcgcagcuaacgcgauaaguagaccgccuggggaguacggucgcaagacu
aaaacucaaaugaauugacgggggcccgcacaagcgguggagcauguggu
uuaauucgaugcaacgcgaagaaccuuaccuggccuugacauacuagaaa
cuuuucagagauggauuggugccuucgggaaccuagauacaggugcugca
uggcugucgucagcucgugucgugagauguuggguuaagucccgcaacga
gcgcaacccuuuuccuuacuugccagcauuucggaugggaacuuuaagga
uacugccagugacaaacuggaggaaggcggggacgacgucaagucaucau
ggcccuuacggccagggcuacacacgugcuacaauggucgguacaaaggg
uugcuacacagcgaugugaugcuaaucucaaaaagccgaucguaguccgg
auuggagucugcaacucgacuccaugaagucggaaucgcuaguaaucgcg
gaucagaaugccgcggugaauacguucccgggccuuguacacaccgcccg
ucacaccaugggaguuuguugcaccagaaguagcuagccuaacugcaaag
agggcgguuaccacgguguggccgaugacuggggugaagucguaacaagg
uagccguaggggaaccugcggcuggauc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<<...<<<<<<..>>>>>>...>>>.>>>>>
......<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<
<......>>>>>......>>.>.....<<<....>>>....<<<<<<..<
<....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>
>>>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<
<<<......<<<<....>>>>.....>>>>...<.<<<<<......<<<<
<<<<<<.<...>.>>>>>>.>>>>........>>>>>....>..<<<<<(
((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>
>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<
......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<
<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>......
>>>>>>>>...........<<....>>.>>>>>>>..>>>.>>>>>...>
>>...>>>>....<<<<<<...<<...<<<<.........>>>>...>>>
>>>>>..........<<<<<<..<<<<<<<<<<<<<...>>>>>>>>>>>
>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<
......<<........>>..........<<<<<<<......<<<<<<...
<..<<<<....>>>>..>...<<....>>...>>>>.>>.<<<.<<<..<
<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>
>>.....<<<<.<<<<<<....<<..<<<.....>>>>>.....>>>>>>
.....<<<<<.....>>>>>........>>>>.........>>>...>>>
>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<
..<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<..
..<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<
<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<
.<.<<<<.<<<..<<<.<<<<<<<<....<<<<<<.<<<<..<<....>>
.>>>>>>>>>>...>>>>>>>>.>>>..>>>.>>>>..>.>>...>....
.<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB7m4x Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii.
Resolution2.66 Å
Binding residue
(original residue number in PDB)
R23 W25 P27 G100 T104 N105 K145 I173
Binding residue
(residue number reindexed from 1)
R20 W22 P24 G97 T101 N102 K142 I170
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7m4x, PDBe:7m4x, PDBj:7m4x
PDBsum7m4x
PubMed34044590
UniProtV5VBC2

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