Structure of PDB 6zm6 Chain b Binding Site BS01

Receptor Information
>6zm6 Chain b (length=150) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREV
IDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLV
QKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDP
Ligand information
>6zm6 Chain A (length=1531) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaaugaacugacaauua
acagcccaauaucuacaaucaaccaacaagucauuauuacccucacuguc
aacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaa
cucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagcauc
accaguauuagaggcaccgccugcccagugacacauguuuaacggccgcg
guacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauaggga
ccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaaccag
ugaaauugaccugcccgugaagaggcgggcauaacacagcaagacgagaa
gacccuauggagcuuuaauuuauuaaugcaaacaguaccaaaccugcauu
aaaaauuucgguuggggcgaccucggagcagaacccaaccuccgagcagu
acaugcuaagacuucaccagucaaagcgaacuacuauacucaauugaucc
aauaacuugaccaacggaacaaguuacccuagggauaacagcgcaauccu
auucuagaguccauaucaacaauaggguuuacgaccucgauguuggauca
ggacaucccgauggugcagccgcuauuaaagguucguuuguucaacgauu
aaaguccuacgugaucugaguucagaccggaguaauccaggucgguuucu
aucuacuuucaaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacccacccaagaacaggguuugu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>.<.<<<......>>>.>..<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<<..<<<<........<<<<<.<<.....>>.>>>>>.....
.<<<...<<<<.......................>>>>.......>>>..
...<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<...
......<......<<<<<<..<<<.........>>>...<<<<<<.....
........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><<<<
<<......>>>>>>........<...........<<<<<<.....>>>>>
>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>
>.....>.....<<<<<........>>>>>.......<<..<<<.<<...
...<<<<.<<<<<<..<<<<<.<<<<<<<<....<..>......>>>>>>
>>>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<.
....<<<..<<<<.....>>>>..>>>...........>>.........<
<<....>>>............>>>>..>>>>>>.......<<<..<.<<<
<<<...<<.......>>...>>>>>>...>.>>.>.......<<<<<.<<
<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>..
...>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....>>.
.>>>.>>...<.<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<................>>>.....
.>..........<<<<.......>>>>....
Receptor-Ligand Complex Structure
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PDB6zm6 Mechanism of membrane-tethered mitochondrial protein synthesis.
Resolution2.59 Å
Binding residue
(original residue number in PDB)
X2 A3 R4 D36 A38 C71 V72 R74 H90 R114 R116
Binding residue
(residue number reindexed from 1)
X1 A2 R3 D35 A37 C70 V71 R73 H89 R113 R115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6zm6, PDBe:6zm6, PDBj:6zm6
PDBsum6zm6
PubMed33602856
UniProtQ8N983|RM43_HUMAN Large ribosomal subunit protein mL43 (Gene Name=MRPL43)

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