Structure of PDB 6tnn Chain b Binding Site BS01

Receptor Information
>6tnn Chain b (length=123) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIETKKVVVEEIASKLKESKSTIIVDYRGLNVSEVTELRKQLREANVEFK
VYKNTMTRRAVEQAELNGLNDFLTGPNAIAFSTEDVVAPAKVLNDFAKNH
EALEIKAGVIEGKVSTVEEVKAL
Ligand information
>6tnn Chain U (length=2930) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgguuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccg
augaaggacgggacgaacaccgauaugcuucggggagcuguaagcaagcu
uugauccggagauuuccgaauggggaaacccaccacucguaauggagugg
uauccauaucugaauucauaggauaugagaaggcagacccggggaacuga
aacaucuaaguacccggaggaagagaaagcaaaugcgauucccugaguag
cggcgagcgaaacgggaucagcccaaaccaagaggcuugccucuuggggu
uguaggacacucuguacggaguuacaaaggaacgagguagaugaagaggu
cuggaaaggcccgccauaggagguaacagcccuguagucaaaacuucguu
cucuccugaguggauccugaguacggcggaacacgugaaauuccgucgga
auccgggaggaccaucucccaaggcuaaauacucccuagugaccgauagu
gaaccaguaccgugagggaaaggugaaaagcaccccggaaggggagugaa
agagauccugaaaccgugugccuacaaguagucagagcccguuaacgggu
gauggcgugccuuuuguagaaugaaccggcgaguuacgaucccgugcaag
guuaagcagaagaugcggagccgcagcgaaagcgagucugaauagggcgc
augaguacguggucguagacccgaaaccaggugaucuacccauguccagg
gugaaguucagguaacacugaauggaggcccgaacccacgcacguugaaa
agugcggggaugagguguggguaggggugaaaugccaaucgaaccuggag
auagcugguucucuccgaaauagcuuuagggcuagccucaagguaagagu
cuuggagguagagcacugauuggacuaggggccccuaccggguuaccgaa
uucagucaaacuccgaaugccaaugacuuauccuugggagucagacugcg
agugauaagauccguagucgaaagggaaacagcccagaccgccagcuaag
gucccaaaguauacguuaaguggaaaaggauguggaguugcuuagacaac
caggauguuggcuuagaagcagccaccauuuaaagagugcguaauagcuc
acuggucgagugacucugcgccgaaaauguaccggggcuaaacguaucac
cgaagcugcggacuguucuucgaacagugguaggagagcguucuaagggc
ugugaagccagaccggaaggacugguggagcgcuuagaagugagaaugcc
gguaugaguagcgaaagaggggugagaauccccuccaccgaaugccuaag
guuuccugaggaaggcucguccgcucaggguuagucgggaccuaagccga
ggccgaaaggcguaggcgauggacaacagguugauauuccuguaccaccu
ccucaccauuugagcaauggggggacgcaggaggauaggguaagcgcggu
auuggauauccgcguccaagcaguuaggcugggaaauaggcaaauccguu
ucccauaaggcugagcugugauggcgagcgaaauauaguagcgaaguucc
ugauuccacacugccaagaaaagccucuagcgaggugagaggugcccgua
ccgcaaaccgacacagguaggcgaggagagaauccuaaggugaucgagag
aacucucguuaaggaacucggcaaaaugaccccguaacuucgggagaagg
ggugcucuguuagggugcaagcccgagagagccgcagugaauaggcccag
gcgacuguuuagcaaaaacacaggucucugcgaagccguaaggcgaagua
uaggggcugacgccugcccggugcuggaagguuaagaggagcgcuuagcg
uaagcgaaggugcgaauugaagccccaguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgacccgcacga
aaggcgcaacgaucugggcacugucucaacgagagacucggugaaauuau
aguaccugugaagaugcagguuacccgcgacaggacggaaagaccccgug
gagcuuuacugcagccugauauugaauguugguacagcuuguacaggaua
gguaggagccuuggaaaccggagcgccagcuuugguggaggcaucggugg
gauacuacccuggcuguauugaccuucuaacccgccgcccuuaucgggcg
gggagacagugucaggugggcaguuugacuggggcggucgccuccuaaaa
gguaacggaggcgcccaaagguucccucagaaugguuggaaaucauucgc
agaguguaaaggcacaagggagcuugacugcgagaccuacaagucgagca
gggacgaaagucgggcuuagugauccggugguuccgcauggaagggccau
cgcucaacggauaaaagcuaccccggggauaacaggcuuaucucccccaa
gaguccacaucgacggggagguuuggcaccucgaugucggcucaucgcau
ccuggggcuguagucggucccaaggguugggcuguucgcccauuaaagcg
guacgcgagcuggguucagaacgucgugagacaguucggucccuauccgu
cgcgggcgcaggaaauuugagaggagcuguccuuaguacgagaggaccgg
gauggacgcaccgcugguguaccaguuguucugccaagggcaucgcuggg
uagcuaugugcggacgggauaagugcugaaagcaucuaagcaugaagccc
cccucaagaugagauuucccauuccgcaaggaaguaagaucccugaaaga
ugaucagguugauaggucugagguggaaguguggcgacacauggagcuga
cagauacuaaucgaucgaggacuuaaccau
..<<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.
.....<<<<<<.....((.>>>.....<<<<<<<..<<.))......>>.
....>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>
>.<<<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<<
....>>......>>>>>.>.........<<....>>...<<<<......<
<.....>>.....>>>>...(((....<<<<<<<<....>>>>>>>>...
...<<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<
<......>>>>.((......<<<.....))>>>...>>>...>>>>>>>>
>>>>>>.>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>..
....<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]......
.........<<....>>....]].........<<<<....>>>>......
.......}....>>>>>>>>>>>.......<<<<..<<<<......>>>>
..>>>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<
<<...<<<.....>>>...>>>...<<....>>..<<<<.....>>>>..
....>>>>>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<
<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<.......
.>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>..
.>..>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<
<<<<<.....<<<...<<<<<<<<......<<<<.....>>>>.......
>>>>>>>>..>>.>.....>>>>.>>>>>..>>>>>>>.>>..<<<<<<<
.<<......>>.>>>>>>>....<<<......>>>...<<<<.<<<...<
<<(((.....<<<<<<...........<<..<<<<<<<<<........<<
<<<.<<.....................>>.........<<......>>..
.>>>>>....>>>>>>>>>.>>...........))).....>>>>>>.>>
>...>>>>>>><<<<<<<...>>>>>>>....>>>>>><.<<<<<<<.<<
......<<<<<.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>
>>><......<<....<<<<<<.......>>>>>><<<<....<<<<<.<
<<..<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<..
.<<<....>>>...>>>...>>...<<<<<........>>>>>))<<<<<
.<<<<<<......<<...<<<<....<<<<..<<<..<<<.<.<<<.<..
...{....>.>>>.<<..<......<<.<.<<<<<<<.<<.....>>>>>
>>>>.....>>>......>...>><..<<...........>>...>>.>>
>...>>>...>>>>.........>>>>..>>..>>>>>>>>>>>>>>>.>
>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<..
..<<<<<<<<.<<<........<.....<<<<<....<<..>>.....>>
>>><<<<<....<<<<....>>>>...>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<<....>>>......
.>>>>>>>..<<<<.<<<..<<<<<<<..<<<...<<...<<<<<..<<.
...>>...>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<.......>>>>>.....>..
..>>>>...>>.>>>>>>>..>.>>>.>>>>>>>>.>>>>>>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<<<<<<<.<<<.<<<..<<<<<<............
<<<<<..<<...............................>>........
....>>>>>..>.>>>>>..>>>.>>>....<<.<<<<<.......>>>>
>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<.....
......>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>..
...<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>
>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>
>>.............>>>>..]]>>>>.......<<<<...<<<<<<...
<<.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..
<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>
>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>
>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>
>>>>>.<<<<<...<<<<...<<<<<<<<<<<.}..>>>>>>..>>>>>.
..>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>
.>>>>.......>>>>>>>..<<<<....>>>>....<<<<<<<<<....
...>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..
>>>>>.>>>...>>>>....>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6tnn Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		T7 K8 D29 Y30 R31 G32 L33 N34 E37 L41 R42 V50 V54 Y55 K56 N57 T58 M59 R61 E65 G78 P79 N80
Binding residue
(residue number reindexed from 1)		T4 K5 D26 Y27 R28 G29 L30 N31 E34 L38 R39 V47 V51 Y52 K53 N54 T55 M56 R58 E62 G75 P76 N77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6tnn, PDBe:6tnn, PDBj:6tnn
PDBsum6tnn
PubMed32991829
UniProtP42923|RL10_BACSU Large ribosomal subunit protein uL10 (Gene Name=rplJ)

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