Structure of PDB 6s0x Chain b Binding Site BS01

Receptor Information
>6s0x Chain b (length=226) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKV
DEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGL
LTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGG
IRDMKSMPQALFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVI
PANDDAIRAVKLLTAKMADAILEGQQ
Ligand information
>6s0x Chain a (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
.....<<<<..[.((((.>>>>.<<<<.<<<<<...<<<<<<<.....<<
<.<<<..<<<..<<.<<<<......................>>>>.>>>>
>......<<........<<<<<<<..<<...<<<<<.<.<<<.<....<<
<<<<....>>>>>>......>>>>......<<<.<...........>.>>
>.......<.<.........>>..>.>>>>>..>>>>>>>>>.<<<....
<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<
....>>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>....<<<.......................>>>......<<<<<
...........<<<<<........>>>>>............>>>>>....
...<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<........<<<......
>>>...........>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>...>>>>....<.<<<<....<...<<<<.........>
>>>...>.>>>>.>..........<<<<<<..<<<<<<<<<<<<<....>
>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<
<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<..<<<<<..
<<<<<<<<<<......<<........>>..........<<<<<<<.....
...<<<......<<<<<....>>>>>.....<<<....>>>....>>>..
......<<<...<<<<<<......<<<<<<<<<....>>>..<<<<....
..>>>>..>>>>>>.....<<<..<<.<<.........<<......>>..
.......>>>>.....<<<<<.....>>>>>.........>>>.......
>.>>>...>>.>>>......>>>>>>>...>>.>>>>>>>>.....<<<<
<<<.....<<<..<<....<<....>>....>>....>>>.....>>>>>
>>......<....<<<<.<<........>>.>>>>....>.....>>>>>
.....<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.
>>....<..<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<
<............>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB6s0x Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Resolution2.425 Å
Binding residue
(original residue number in PDB)		R21 R95 L97 G98 T102 N103 R110 R113 K139 N171 K178
Binding residue
(residue number reindexed from 1)		R21 R95 L97 G98 T102 N103 R110 R113 K139 N171 K178
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6s0x, PDBe:6s0x, PDBj:6s0x
PDBsum6s0x
PubMed31391518
UniProtA0A2X2M020

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